Flashcards in Ch.23: Beta Blockers (Swift) Deck (15):
where are B1 receptors found?
where are B2 receptors found
bronchial and vascular smooth m. Some in myocardium
stimulation of B receptors leads to:
increase in contractility, SA node discharge rate and AV node conduction
stim. of B2 receptors leads to:
-increase SA node discharge rate, AV node conduction
effects of beta blockade
-decrease SA node firing rate --> decr. HR, improved myocardial perfusion
-slowed AV node conduction
-dec. myocardial contractility --> less myocardial O2 consumption
uses of beta blockers**
-anti-arhythmic (esp. for SVTs and VTs)
-CHF when active heart failure is resolved**
side effects of beta blockers
-bradycardia, AV block, neg. ionotropic effect
-depression, lethargy, insomnia
is propanolol selective?
No. Therefore, creates greater decrease in HR than other B-blocers
is atenolol selective?
yes, for B1
propanolol lipid or water soluble?
atenolol lipid or water soluble?
rank duration of action of propanolol, esmolol, and atenolol*
atenolol > propanolol > esmolol
main use of esmolol
acute anti-arrhythmic agent for SVTs
is sotalol selective?