Ch3 Membranes Flashcards

1
Q

Fluid Mosaic Model

A

Used to model how biomolecules are combined to form a structure (like cell membrane)

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2
Q

3 components of Biomembrane
Which is the main

A
  1. Phospholipid bilayer (MAIN)
  2. Proteins
  3. Carbohydrates
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3
Q

Each membrane has

A

A unique composition of lipids and proteins suited for its functions

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4
Q

Glycoproteins and glycolipids

A

Sugars linked to proteins and sugars linked to phospholipids on the outside of the membrane

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5
Q

Membrane is fluid due to

A

Kinetic/thermal energy that causes motion in the phospholipids

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6
Q

Cholesterol

A

Rigid molecule
Integrates itself in the phospholipid bilayer
Hydrophobic-Interacts w tails

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7
Q

Membrane fluidity increases as Cholesterol

A

Cholesterol decreases
Less rigidity and structure

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8
Q

Membrane fluidity increases as unsaturated fatty acids

A

Increase.
Cause the tails to be bent, and allows for more fluidity

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9
Q

Membrane fluidity increases as temperature

A

Increases
More energy more movement more fluidity

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10
Q

3 kinds of membrane proteins

A

1.Integral Proteins
2.Peripheral Membrane Proteins
3.Glycoproteins

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11
Q

Integral proteins

A

Embedded in the membrane. Amphipathic
Can be in just 1 side or go all the way through

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12
Q

Transmembrane protein

A

When a integral protein goes all the way through the membrane

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13
Q

Peripheral membrane protein

A

Loosely bound to inside of membrane
Often bound to integral membrane proteins
Helps give structure to the cell

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14
Q

Glycoproteins

A

Proteins with carbohydrates covalently bonded

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15
Q

Biomembranes are

A

Asymmetrical

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16
Q

6 functions of MP

A

1.transport
2.enzymatic activity
3.signal transduction
4.cell-cell recognition
5.intercellar joining
6.Attatchment to cytoskeleton+extracellular matrix

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17
Q

Signal transduction

A

Protein acts as a receptor. Signal molecule binds and relays message to inside the cell.

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18
Q

Cell-Cell recognition

A

Glycoproteins/lipids act as molecular markers for the immune system
(Tcells)

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19
Q

Intracellular joining

A

Physical linking of the plasma membrane of adjacent cells

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20
Q

Attatchment to cytoskeleton and extracellular matrix serves

A

Many different functions including cell shape

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21
Q

Permeable

A

Substance that can pass

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22
Q

Impermeable

A

Substance that can not pass

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23
Q

Permeability is controlled

A

By the opening and closing of specific channels

24
Q

What 2 factors influence permeability

A
  1. Solubility of molecule in lipids
    Lipid soluble-Pass Freely
  2. Size of the molecule Smaller=more permeable
25
Lipid soluble molecules are
Hydrophobic Non polar or uncharged Pass freely through membrane
26
Lipid insoluble molecules
Hydrophillic Polar or charged Do not pass freely through membrane
27
Passive transport
High to low energy/conc Favored by entropy/can be spontaneous No energy is required
28
2 kinds of passive transport (One has 2 names)
Simple diffusion Carrier mediated/Facilitated diffusion
29
2 kinds of Facilitated diffusion Aka
Channel proteins- Provides Hydrophillic pathways to allow water/small ions to pass freely Carrier Proteins- (oyster) undergo subtle changes in protein conformation/shape -allows translocation of specific molecule
30
Simple diffusion Occurs until
Molecules go from high to low conc Until equilibrium is reached Movement still occurs but equally
31
Large molecules diffuse
Slower than small ones
32
Diffusion can only occur if
The membrane is PERMEABLE to the molecule
33
Hydrophobics can diffuse
Through the membrane directly
34
Hydrophilics must
Use other channels to cross the membrane
35
Osmosis
Diffusion of water across membranes
36
Most membranes are freely permeable to
Water
37
The concentration of water and concentration of solute
Are inversely proportional. As one increase the other decreases.
38
Tonicity Predicts the
Used to describe the solute in a solution relative to the solute in a typical cell. Predicts the magnitude + direction of osmosis
39
Isotonic
Equal amount of solute inside and outside the cell
40
Hypertonic
Concentration of solute is greater outside the cell than inside the cell. Cause cell to be shriveled
41
Hypotonic
Concentration of solute inside the cell is greater than the concentration outside of the cell Causes cell to be lysed/burst open
42
Terms for tonicity for plant cells
Isotonic Flaccid Hyper- Plasmolyzed Hypo- Turgid
43
Primary active transport Ex?
Directly used energy from an ATP molecule Ex. Protein pumps/ Sodium Potassium pump ATPase
44
How does the sodium potassium pump work For every 1 ATP molecule,
1) In the cytoplasm, low NA high K. 3 NA and ATP bind. 2) ATP hydrolizes. Phosphate attaches to protein. 3. Protein configuration changes. Low affinity for NA. They are released 4. Protein now has high K affinity. 2 Ks from outside bind. Phosphate falls off 5. Pump returns to original shape. 6.2 Ks are released Cycle continues. 3 NA 2 K
45
Membrane potential
Difference in electrical potential between interior and exterior of membrane. Inside- negative Outside- positive
46
A protein pump is
Active transport
47
Secondary active transport
Uses STORED energy from HC, so that when a driving ion like H goes from HC-LC, that energy is used to drive a 2nd molecule against its gradient
48
Secondary active transport is aka
Cotransport
49
Small, hydrophobic molecules use ____ while large Hydrophillic molecules and ions use ____
Simple diffusion Facilitated diffusion
50
MACRO molecules move across the membrane in 2 ways
Membrane bound vessels Exocytosis- molecules moving out of the cell Endocytosis- molecules moving into the cell
51
3 kinds of endocytosis
Phagocytosis Pinocytosis Receptor-Mediated Endocytosis
52
Phagocytosis Some or all cells
LARGE molecules brought into the cell “Cell eating” Some cells
53
Pinocytosis Some or all cells
Small molecules brought into the cell “Cell drinking” ALL cells
54
Receptor mediated endocytosis
Selectively bringing LARGE molecules into the cell. The cell membrane become the exterior of the vessel after a canyon is formed The interior is called the lumen
55
Hat is the job of the bio membrane
The separate compartments