Ch3 Membranes Flashcards
Fluid Mosaic Model
Used to model how biomolecules are combined to form a structure (like cell membrane)
3 components of Biomembrane
Which is the main
- Phospholipid bilayer (MAIN)
- Proteins
- Carbohydrates
Each membrane has
A unique composition of lipids and proteins suited for its functions
Glycoproteins and glycolipids
Sugars linked to proteins and sugars linked to phospholipids on the outside of the membrane
Membrane is fluid due to
Kinetic/thermal energy that causes motion in the phospholipids
Cholesterol
Rigid molecule
Integrates itself in the phospholipid bilayer
Hydrophobic-Interacts w tails
Membrane fluidity increases as Cholesterol
Cholesterol decreases
Less rigidity and structure
Membrane fluidity increases as unsaturated fatty acids
Increase.
Cause the tails to be bent, and allows for more fluidity
Membrane fluidity increases as temperature
Increases
More energy more movement more fluidity
3 kinds of membrane proteins
1.Integral Proteins
2.Peripheral Membrane Proteins
3.Glycoproteins
Integral proteins
Embedded in the membrane. Amphipathic
Can be in just 1 side or go all the way through
Transmembrane protein
When a integral protein goes all the way through the membrane
Peripheral membrane protein
Loosely bound to inside of membrane
Often bound to integral membrane proteins
Helps give structure to the cell
Glycoproteins
Proteins with carbohydrates covalently bonded
Biomembranes are
Asymmetrical
6 functions of MP
1.transport
2.enzymatic activity
3.signal transduction
4.cell-cell recognition
5.intercellar joining
6.Attatchment to cytoskeleton+extracellular matrix
Signal transduction
Protein acts as a receptor. Signal molecule binds and relays message to inside the cell.
Cell-Cell recognition
Glycoproteins/lipids act as molecular markers for the immune system
(Tcells)
Intracellular joining
Physical linking of the plasma membrane of adjacent cells
Attatchment to cytoskeleton and extracellular matrix serves
Many different functions including cell shape
Permeable
Substance that can pass
Impermeable
Substance that can not pass
Permeability is controlled
By the opening and closing of specific channels
What 2 factors influence permeability
- Solubility of molecule in lipids
Lipid soluble-Pass Freely - Size of the molecule Smaller=more permeable