Ch4 - 1) Primary Hemostasis and Bleeding Related Disorders Flashcards Preview

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Flashcards in Ch4 - 1) Primary Hemostasis and Bleeding Related Disorders Deck (67)
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61

Treatment for microangiopathic hemolytic anemia?

involves plasmapheresis and corticosteroids, particularly in TTP.

62

What are the qualitative platelet disorders?

bernard-soulier, Glanzmann thrombasthenia, asprin, uremia

63

Bernard-Soulier syndrome

is due to a genetic GPIb deficiency; platelet adhesion is impaired.

64

In Bernard-Soulier what lab test are you interested in?

Blood smear which shows mild thrombocytopenia with enlarged platelets.

65

Glanzmann thrombasthenia is due to?

a genetic GPIIb/IIIa deficiency; platelet aggregation is impaired.

66

Aspirin and microangiopathic hemolytic anemia?

it irreversibly inactivates cyclooxygenase; lack of TXA, impairs aggregation.

67

Uremia and microangiopathic hemolytic anemia

disrupts platelet function; both adhesion and aggregation are impaired.