Flashcards in Ch4 - 1) Primary Hemostasis and Bleeding Related Disorders Deck (67)
Treatment for microangiopathic hemolytic anemia?
involves plasmapheresis and corticosteroids, particularly in TTP.
What are the qualitative platelet disorders?
bernard-soulier, Glanzmann thrombasthenia, asprin, uremia
is due to a genetic GPIb deficiency; platelet adhesion is impaired.
In Bernard-Soulier what lab test are you interested in?
Blood smear which shows mild thrombocytopenia with enlarged platelets.
Glanzmann thrombasthenia is due to?
a genetic GPIIb/IIIa deficiency; platelet aggregation is impaired.
Aspirin and microangiopathic hemolytic anemia?
it irreversibly inactivates cyclooxygenase; lack of TXA, impairs aggregation.