Chapter 10 Notes Flashcards

(71 cards)

1
Q

Metabolism total of a chemical reactions in the cell and is divided into two parts, called:

A

catabolism and anabolism

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2
Q

contribute to cycling of elements in ecosystem

A

microbial metabolism

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3
Q

synthesis of complex molecules

A

chemical work

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4
Q

take up of nutrients, elimination of wastes and maintenance of ion balances

A

transport work

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5
Q

cell motility and movement of structures within cells

A

mechanical work

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6
Q

a science that analyzes energy changes in a collection of matter called a system (e.g., a cell)

A

thermodynamics

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7
Q

total energy in universe remains constant,

however, energy may be redistributed either within a system or between the system and its surroundings

A

first law of thermodynamics

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8
Q

Physical and chemical processes proceed in such a way that the disorder of the universe increases to the maximum possible

A

second law of thermodynamics

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9
Q

amount of disorder in a system

A

entropy

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10
Q

amount of heat energy needed to raise 1 gram of water from 14.5 to 15.5°C

A

calorie

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11
Q

units of work capable of being done by a unit of energy

A

joules

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12
Q

1 cal of heat is equivalent to ___ J of work

A

4.1840

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13
Q

Expresses the change in energy that can occur in chemical reactions and other processes

A

free energy and reactions

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14
Q

if delta G is negative

A

reaction is spontaneous

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15
Q

if delta G is positive

A

reaction is non spontaneous

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16
Q
  • free energy change

- unit of energy available to do work

A

delta G

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17
Q

-change in enthalpy (heat content)

A

delta H

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18
Q
  • temp in kelvin

- change in entropy

A

T

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19
Q

chemical equilibrium

A

delta S

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20
Q

Free energy change defined at standard conditions of:

A

concentration, pressure, temperature, and pH

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21
Q

standard free energy change at what pH?

A

7

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22
Q

Exergonic reactions

A

Delta G degrees is negative

reaction proceeds spontaneously

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23
Q

endergonic reactions

A

Delta G degrees is positive

reaction will not proceed spontaneously

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24
Q

The Energy Currency of the Cell

A

ATP

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25
__ breakdown of high energy ATP is coupled with __reactions to make them more favorable
exergonic, endergonic
26
ATP is said to have a HIGH what?
phosphate transfer potential
27
it readily sends a __ ___ to other molecules
phosphate group
28
other molecules have higher phosphate transfer potential than __
ATP
29
ATP = __ and the phosphate from those molecules
ADP
30
Located in plasma membranes of chemoorganotrophs in bacteria and archaeal cells
electron carriers
31
Electron carriers located in internal mitochondrial membranes in ___ cells
eukaryotic
32
main electron carriers located in plasma membranes of ___ in bacteria and archaeal cells
chemoorganotrophs
33
NAD means
nicotinamide adenine dinucleotide
34
NADP means
nicotinamide adenine dinucleotide phosphate
35
FAD, FMN, coenzyme are all
additional electron carriers
36
use iron to transfer electrons
cytochrome
37
example of Nonheme iron-sulfur proteins
ferrodoxin
38
in biochemical pathway__ can be linked together to form pathways
enzymes
39
in biochemical pathway, Pathways can be varied in what shapes?
linear cyclic Branching
40
biochemical Pathways often __ or __ into each other
overlap or feed
41
biochemical pathways are dynamic pathways can be | used to monitor changes in __ levels (flux)
metabolite
42
Carry out reactions at physiological conditions so they proceed in a timely manner
enzymes
43
Enzymes speed up the rate at which a reaction proceeds toward its final ___
equilibrium
44
- high specificity for the reaction catalyzed and the molecules acted on - substance that increases the rate of a reaction without being permanently altered
protein catalysts
45
reacting molecules
substrates
46
substances formed by reaction
products
47
protein component of an enzyme
Apoenzyme
48
nonprotein component of an enzyme
cofactor
49
energy required to form transition-state complex
activation energy
50
How enzymes lower Ea
- By increasing concentrations of substrates at active site of enzyme - By orienting substrates properly with respect to each other in order to form the transition-state complex
51
Enzyme activity is significantly impacted by
- substrate concentration - pH - temperature
52
Rate increases as [substrate] increases or decreases?
increases
53
No further increase occurs after all enzyme molecules are saturated with __
substrate
54
loss of enzyme’s structure and activity when temperature and pH rise too much above optima
denaturation
55
when it comes to enzyme inhibition, __ ___ directly competes with binding of substrate to active site
competitive inhibitor
56
- binds enzyme at site other than active site | - changes enzyme’s shape so that it becomes less active
noncompetitive inhibitor
57
__ and __ discovered that some RNA molecules also can catalyze reactions
Thomas Cech and Sidney Altman
58
Thomas Cech and Sidney Altman discovered that some RNA molecules also can catalyze reactions, some examples of that are:
- catalyze peptide bond formation - self-splicing - involved in self-replication
59
Important for conservation of energy and materialsq
regulation of metabolism
60
When it comes to regulation of metabolism, Maintenance of metabolic balance despite changes in ___
environment
61
When it comes to the regulation of metabolism, there are three major mechanisms:
- metabolic channeling - regulation of the synthesis of a particular enzyme (transcriptional and translational) - direct stimulation or inhibition of the activity of a critical enzyme (post translational)
62
Differential localization of enzymes and metabolites
metabolic channeling
63
differential distribution of enzymes and metabolites among separate cell structures or organelles
compartmentation
64
can generate marked variations in metabolite concentrations
compartmentation
65
when it comes to Post-Translational Regulation of Enzyme Activity, Two important reversible control measures are:
- allosteric regulation | - covalent modification
66
Reversible on and off switch
Covalent Modification of Enzymes
67
covalent modification of enzymes, Addition or removal of a __ group (phosphate, methyl, adenyl
chemical
68
Inhibition of one or more critical enzymes in a pathway regulates entire pathway
feedback inhibition
69
catalyzes the slowest or rate-limiting reaction in the pathway
peacemaker enzyme
70
Feedback Inhibition: - Each end product regulates its own branch of the ___ - Each end product regulates the initial ___ enzyme
pathway, peacemaker
71
different enzymes that catalyze same reaction
isoenzymes