Chapter 15 Flashcards

(35 cards)

1
Q

When should antiepileptic drugs be given

A

Before any other med

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2
Q

What is a seizure

A

Abnormal electrical activity in brain

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3
Q

What is a convulsion

A

Spastic contractions of muscles

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4
Q

What is epilepsy

A

Chronic pattern of seizures

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5
Q

What is difference between primary and secondary epilepsy

A

Primary: unknown cause
Secondary: known cause

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6
Q

What are febrile seizures

A

Occur in children 6months to 5 years caused by fever

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7
Q

What are tonic clonic seizures

A

The person convulses

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8
Q

What are atonic seizures

A

The person collapses

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9
Q

What are focal seizures

A

Person stares into space

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10
Q

What are the 3 stages of seizures

A

Prodrome: beginning
Ictal: middle
Post ictal: end

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11
Q

What is status epilepticus

A

Multiple seizures
Last more than 5 mins
Medical emergency

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12
Q

What is the drug of choice for treating status epilepticus

A

Diazepam

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13
Q

What to antiepileptic drugs do

A

Slow down nerve impulses
Increase GABA

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14
Q

Which anti epileptic drug is also used for neuropathic pain

A

Gabapentin

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15
Q

Long term therapy of phenytoin causes

A

Gingival hyperplasia

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16
Q

Should Dilantin be given during pregnancy

A

No causes spina bifida

17
Q

Do not give what with phenytoin

A

Warfarin, increases bleeding

18
Q

Carbamazepine increases metabolism of

A

Acetaminophen

19
Q

Valproic acid toxicity increases when given with

20
Q

Why do anti epileptic drugs need lab monitoring

A

Have narrow therapeutic index

21
Q

Most common adverse effect of phenobarbital and primidone is

22
Q

What is the relationship between phenobarbital and primidone

A

The liver turns primidone into phenobarbital

23
Q

What med is used for febrile seizures

A

Phenobarbital or primidone

24
Q

Vitamin D is taken with which med to prevent osteoporosis

A

Phenytoin sodium

25
If phenytoin sodium is given to fast it causes
Cardiac dysrhythmias and respiratory depression
26
What med cannot be taken with grapefruit
Carbamazepine
27
Which drug causes auto induction of hepatic enzymes (liver breaks down med faster and faster each time) dose has to be increased over time
Carbamazepine
28
What drug is used for focal seizures
Ethosuximide
29
What med is also used to treat bipolar disorder
Lamotrigine
30
Lamotrigine causes DRESS side effect. What is it
Drug reaction with eosinophillia and systemic symptoms
31
How can DRESS be avoided with Lamotrigine
Titrate over several weeks
32
What med is safe during pregnancy
Lamotrigine
33
Which med should not be taken with carbonated beverages
Valproic acid
34
Which med has sleepiness as side effect
Levetiracetam
35
Which med needs serum albumin levels checked before started
Phenytoin