Chapter 19-20

Question 1

Type 1 Hypersensitivity

Answer 1

IgE and Mast cells. Soluble antigen

Question 2

Type 2 Hypersensitivity

Answer 2

IgG and IgM. Cell bound antigen

Question 3

Type 3 Hypersensitivity

Answer 3

IgG and IgM. Soluble antigen

Question 4

Type 4 Hypersensitivity

Answer 4

T cell mediated. Soluble or cell bound antigen

Question 5

Diabetes

Answer 5

T cell dependent autoimmune disease. Selective destruction of the B cells of the islets of Langerhaans

Question 6

IgM

Answer 6

Complement activation

Question 7

IgG

Answer 7

Opsonization and complement activation

Question 8

IgA

Answer 8

Mucosal immunity

Question 9

IgE

Answer 9

Helminths / protozoa and allergy

Question 10

4 outcomes of complement

Answer 10

Inflammation, opsonization, chemotaxis and cytolysis

Question 11

4 functions of antibodies

Answer 11

Agglutination, opsonization, neutralization, complement activation

Question 12

MHC 1

Answer 12

Used by all nucleated cells. Presents peptides from within the cell.

Question 13

MHC 2

Answer 13

Only used by professional APC cells. Presents peptides taken up by phagocytes and digested.

Question 14

Dendritic cells

Answer 14

Secrete cytokines when activated by pathogens. Required to activate CD4+ T cells