chapter 2 Flashcards
what are the functions of granules?
Release contents into the extracellular space upon activation of the cell
hematoxylin stains
structures blue
basic/positive so stains acidic structures such as nucleic acids
Eosin
acidic and negative so stains basic structures pink such as granules in basophils
what granulocyte is not phagocytic ?
basophil
specialized macrophages include:
osteoclasts (bone), microglia cells (CNS), alveolar macrophages (lung), kupffer cells (liver)
what lineage are macrophages from?
myloid and develop from a monocyte
dendritic cells are of what origin?
myloid and lymphoid
how are Follicular DC different from dendritic cells?
from a different lineage where FDC is from lymphoid origin and is found in the lymph nodes, binds to Ab:Ag complexes and is important for B cell activation and maturation
what cells of the lymphoid lineage interacts with antigen?
B lymphocytes and T lymphocytes
B lymphocytes produce_____ and act as______
antibodies and pAPCs
T lymphocytes interact with
Antigen presenting cells or target cells
natural killer cells directly kill
tumor cells and virally infected cells
to make antibodies a cell must have lots of
endoplasmic reticulum
innate lymphoid cells secrete what?
cytokines to initiate defence
B cells interact with _____ and differentiate into _________
anigens
antibody-secreting plasma cells that bind antigens and facilitate clearance from the body
