Chapter 6 adaptive quiz Flashcards

1
Q

Extensive _____ trimming is more common at the _____ heavy-chain V gene joints than at the light-chain V-J joint.

A

exonuclease, two

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2
Q

Cells destined to become αβ T cells proceed to the DP stage where they are tested for their ability to recognize antigen displayed by immune system cells (_____ selection) without inducing autoimmunity (_____ selection).

A

positive, negative

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3
Q

Like the heavy chain, the light chain:

A

can be rearranged on both homologous chromosomes.

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4
Q

Only three of the proteins implicated in VJ recombination are unique to lymphocytes: _____, _____, and terminal deoxynucleotidyl transferase.

A

Rag 1 and Rag 2

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5
Q

In both heavy and light chains:

A

the number of V regions is greater than the number of J regions.

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