chapter 2: ECM

Question 1

difference btwn epithelium and CT

Answer 1

CT consists mostly of intercellular components and limited # of cells

Question 2

general fxn of CT

Answer 2

provide structural support
provide medium for exchange
defense/protection
storage of adipose

Question 3

provide a structural support

Answer 3

reticular CT and bone

Question 4

provide a medium for exchange

Answer 4

loose CT

Question 5

defense/protection

Answer 5

loose areolar

Question 6

storage of adipose

Answer 6

energy, thermoregulation, cushion organs

Question 7

components of ECM

Answer 7

ground substance

fibers

Question 8

important general trait of GAGs

Answer 8

hydrophilic

Question 9

keratin sulfate
chondroitin sulfate
herapin sulfate
dermatin sulfate

Answer 9

sulfated GAGs

Question 10

hyaluronic acid

Answer 10

nonsulfated GAG

Question 11

smaller molecules

covalently bonded to PROTEINS

Answer 11

sulfated GAGs

Question 12

large molecules
forms a dense molecule network
holds much WATER – important for DIFFUSION

Answer 12

non-sulfated GAGs

Question 13

positive effects of inflammation

Answer 13

increase fluidity will aid cell movement

increase # of defensive cells

Question 14

extra fluid and defensive cells come from:

Answer 14

leaky capillaries and venules

Question 15

negative effects of inflammation

Answer 15

excessive swelling can damage BV, nerves and cells

Question 16

excessive fluid remaining in interstitial spaces

Answer 16

edema

Question 17

protein core with many sulfated GAGs

Answer 17

proteoglycans

Question 18

laminin

fibronectin

Answer 18

adhesive glycoproteins

Question 19

MC CT protein

Answer 19

collagen

Question 20

______ collagen accounts for 90% of total body collagen and is known for great TENSILE strength

Answer 20

type I

Question 21

collagen type that does NOT stretch

Answer 21

type I

Question 22

with agin, fiber production _____ and fibers produced are _____

Answer 22

slows

weaker

Question 23

necessary for proper cross linking within the collagen I fiber

Answer 23

vit C

Question 24

composed of elastin and microfibrils that can stretch 150% of resting length

Answer 24

elastic

Question 25

commonly produced by fibroblasts and smooth muscle cells; important in BV and lungs

Answer 25

elastic

Question 26

as age increase, the # of elastic fibers will ____

Answer 26

decrease

Question 27

reticular is AKA

Answer 27

collagen type III

Question 28

fibers of ECM

Answer 28

collagen elastic reticular collagen (type III)

Question 29

collagen that is NOT affected with aging

Answer 29

reticular

Question 30

first fiber produced during wound healing; common in liver, bone marrow and lymph nodes

Answer 30

reticular