Chapter 2 - The Animal Research Environment

Question 1

The Animal Welfare Act is administered by what agency?

Answer 1

USDA Animal & Plant Health Inspection Service

Question 2

What regulations apply to nonclinical studies conducted to collect data for submission to the Food and Drug Administration (FDA)?

Answer 2

Good Laboratory Practices (GLPs)

Question 3

What committee oversees the institution’s animal research programs?

Answer 3

Institutional Animal Care & Use Committee (IACUC)

Question 4

What agency is responsible for enforcing the Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS Policy)?

Answer 4

Office of Laboratory Animal Welfare (OLAW)

Question 5

True or False

Mice bred for research are not covered by the Animal Welfare Act.

Answer 5

True

Question 6

True or False

The Animal Welfare Regulations is another name for the Animal Welfare Act.

Answer 6

False

The Animal Welfare Regulations describe what rules a facility must follow to comply with the AWA.

Question 7

What document must be submitted to the USDA every year by an animal facility with USDA-covered species?

Answer 7

An annual report

Question 8

Upon request, USDA records are available to the public under what federal act?

Answer 8

Freedom of Information Act

Question 9

Name the person to whom the IACUC is responsible.

Answer 9

Institutional Official

Question 10

The PHS Policy on Humane Care and Use of Laboratory Animals applies specifically to which type of research?

Answer 10

Federally funded research

Question 11

What document must an investigator submit for approval by the IACUC for each research study involving laboratory animals?

Answer 11

Animal use protocol or animal protocol.

Question 12

If research is funded by agencies of the PHS, what document must the Institutional Official send to OLAW about the institution’s animal care and use program?

Answer 12

Animal Welfare Assurance of Compliance Statement or PHS Assurance

Question 13

Name the “3Rs” Principles of Russell and Burch.

Answer 13

Replacement, refinement, and reduction

Question 14

What is the term described in the 3Rs for designing an experiment so that stress or pain to an animal is minimized?

Answer 14

Refinement

Question 15

What is the common term for the policy that most institutions have to protect an individual reporting instances of animal abuse or neglect?

Answer 15

Whistleblower policy