Chapter 23 - Respiratory System Flashcards

(47 cards)

1
Q

respiratory system

A
  • exchange of gases

- moves air to and from exchange surfaces of lungs

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2
Q

mucus

A

along respiratory tracts

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3
Q

Respiratory defense system

A

nose removes large particles

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4
Q

Mucous cells and mucous glands

A

produces mucous to cover exposed surfaces

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5
Q

cilia

A

gather mucus, trapped debris, microorganisms toward pharynx to be swallowed

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6
Q

Alveolar macrophages

A

eat small particles that reach lungs

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7
Q

Bronchioles

A

– Bronchioles branch into terminal bronchioles
– Bronchioles have no cartilage
• Dominated by smooth muscle

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8
Q

autonomic nervous system

A

– Controls bronchioles diameter by regulating smooth muscle

– Controls airflow in lungs

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9
Q

bronchodilation

A

– Caused by sympathetic activation
– Enlarges diameter of airway
– Reduces resistance to airflow

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10
Q

bronchoconstriction

A
  • Parasympathetic activation
    – Reduces diameter of airway
  • Histamine release (allergic reactions)
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11
Q

Alveolar cell layer

A
pneumocytes type I 
-thin walls 
-site of gas exchange 
-monitored by macrophages
pneumocytes type II 
-produces surfactant
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12
Q

surfactant

A

– Oily secretion
– phospholipids + proteins
– Coats alveolar surface and reduces surface tension

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13
Q

respiratory distress syndrome

A

– Alveoli collapse after each exhalation

– Caused by inadequate amounts of surfactant due to injury or genetic abnormalities

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14
Q

Pneumonia

A

– Inflammation of lung tissue
– Causes fluid to leak into alveoli
– Compromises function of blood air barrier

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15
Q

Gas exchange across blood air barrier is quick and efficient

A

– Because distance for diffusion is short

– And O2 and CO2 are small and lipid soluble

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16
Q

Blood pressure in pulmonary circuit

A

– Lower than that in systemic circuit

– Pulmonary vessels are blocked by blood clots, fat, or air bubbles

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17
Q

pulmonary embolism

A

A blocked branch of pulmonary artery that stops

blood flow to lobules or alveoli

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18
Q

external respiration

A

exchange of O2 and CO2 with external environment

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19
Q

internal respiration

A
  • Uptake of O2 and release of CO2 by cells

* Result of cellular respiration

20
Q

hypoxia

A

Low tissue oxygen levels

21
Q

anoxia

A

Complete lack of oxygen in tissues

22
Q

inhalation

23
Q

exhalation

24
Q

the lower the pressure

A

the lower the diffusion

25
resistance
bronchodilation and bronchoconstriction
26
compliance factors that affect compliance?
– A measure of expandability – Lower compliance requires greater force to fill lungs – Factors that affect compliance • Connective tissue of lungs • Level of surfactant production • Mobility of thoracic cage
27
at sea level the partial pressure is
760 mm Hg
28
the other atoms (partial pressure)
N- 78% 0- 21% water vapor - 0.5% CO2- 0.04%
29
solubility of gases in body fluid
– CO2 is highly soluble – O2 is somewhat less soluble – N2 has very limited solubility
30
Partial pressures in plasma of pulmonary vein
– PCO2 =40mmHg – PO2 =100mmHg – PN2 =573mmHg
31
Blood arriving in pulmonary arteries has
* Low PO2 | * High PCO2
32
concentration gradient causes
* O2 to enter blood | * CO2 to leave blood
33
internal respiration what happens?
– Oxygenated blood mixes with deoxygenated blood | – Lowers PO2 of blood entering systemic circuit to about 95 mm Hg
34
interstitial fluid
• PO2 40mmHg,PCO2 45mmHg
35
Concentration gradient in peripheral capillaries is opposite of lungs
• CO2 diffuses into blood, O2 diffuses out of blood
36
red blood cells have a higher affinity for
O and CO2
37
O2 binds to ??? in hemoglobin (Hb) molecules
iron ions • In a reversible reaction • Forming oxyhemoglobin (HbO2)
38
1 RBC has | 1 Hb molecule binds
280 million Hb molecules | 4 oxygen molecules
39
hemoglobin saturation
% heme units containing bound oxygen at any given moment
40
factors affecting Hb saturation
– PO2 of blood – Blood pH – Temperature – Metabolic activity within RBCs
41
When temperature increases, hemoglobin | When temperature decreases, hemoglobin
releases more oxygen | holds oxygen more tightly
42
the more BPG released
more oxygen released | • Due to increase in pH or certain hormones
43
fetal hemoglobin
higher affinity for hemoglobin | • binds more O2 than does adult Hb, takes O2 from maternal blood
44
70% of co2 in solution transported as 23% is
bicarbonate ions (HCO3-) bound to protein portions of Hb molecules in RBCs • Forming carbaminohemoglobin
45
baroreceptors
in aortic or carotid sinuses sensitive to changes in blood pressure
46
aging
elastic tissue deteriorates in lungs
47
Emphysema
- Affects individuals over age 50 | - exposure to respiratory irritants (cigarette smoke)