Chapter 3 Flashcards
The cell is
The structural and functional unit of all living organisms
Cell theory
Schleiden and Schwanna in 1838
The cell is the basic unit of life
All organisms are composed of cells
All cells are derived from other cells
3 major areas of the cell
Cell membrane
Nucleus
Cytoplasm with its organelles
Father of the cell
Robert hook
What is the plasma membrane composed of
Mostly lipid, two major phospholipids and cholesterol
What controls fluidity of the plasma membrane
Cholesterol
Phospholipid bolster
Double layer producing hydrophilic heads and hydrophobic tails
Fluid mosaic model
Neither rigid nor static but dynamic and flexible. Self healing
Membrane potential
Cell membrane is polar as there is a separation of charge across it. Membrane potential is the separation of charge
Charge inside and outside the cell
Positive outside negative inside
Functions of plasma membrane
Regulates what enters and leaves the cell
Itneractions with other molecules occur at the plasmalemma
Delineates intracellular from extra cellular
two categories of proteins of the cell membrane
Peripheral/extrunsic or integral/intrinsic
Peripheral/extrunsic proteins
Attached to either the inner or outer membrane surface. Do not go all the way though the membrane
Integral/inteinsic proteins
Embedded throughout the membrane. Extend from one side to the other. Ex: channel proteins
Membrane proteins
Market molecules
Attachment proteins
Transport proteins - channel, carrier, pumps
Receptor molecules
Market molecules
Mostly glycolipids and glycoproteins - the carbohydrate portions stuck up on extracellular side of cell to allow for cell recognition
Ex- immunity, sperm, antigen markers
Attachment proteins
Proteins in the cell membrane that serve as attachment sites for other cells or extracellular molecules
Transport proteins
Allow ions or molecules to pass from one side of the membrane to the other down the gradient.
Three characteristics with regard to membrane support with transport proteins
Specificity (each carrier binds to only one molecule)
Competition (similar shape compounds might compete for site)
Saturation (rate is limited when all sites are filled)
Channel proteins
Like a tube stuck through the membrane to allow passage of ions or small molecules. Can be open or closed.
Nongated channels
Always open. Ions move down their gradient. Also called leak channels.
Gated channels
Open due to a stimulus
Ligand gated- open when a molecule binds
Voltage gated- open due to a change in charge
Carrier proteins
Move ions from one side to the other with a specific binding shape that changes shape to transport.
Pumps (atp powered)
Move ions or small molecules from one side of the other against their gradient. Ex. Na+/K+ pump