Chapter 4 part 2 Flashcards

(42 cards)

1
Q

What are some Epstein-Barr virus infections

A

Infectious mononucleosis
Nasopharyngeal carcinoma
Burkitt lymphoma
Hairy leukoplakia

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2
Q

In the United States, this occurs primarily among young adolescents and young adults; Kissing disease

A

Infectious mononucleosis

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3
Q

Hairy leukoplakia

A

An irregular, corrugated, white lesions most commonly occurring on the later border of the tongue
Most commonly with pts infected with HIV

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4
Q

How are Coxsackievirus infections transmitted

A

Fecal-oral contamination
Saliva
Respiratory droplets

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5
Q

The three distinctive oral lesions with Coxsackievirus infections

A

Herpangina
Hand-foot-mouth disease
Acute lymphonodular pharyngitis

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6
Q

Herpangina

A
Fever
Malaise
Sore throat
Dysphagia
Vesicles on the soft palate
Erythematous pharyngitis
*Resolves in less then 1 week without treatment
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7
Q

Hand-foot-mouth disease

A

Usually occurs in epidemics in children younger than 5 years of age
Resolves within 2 weeks

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8
Q

Multiple macules or papules occur on the skin, typically on the feet, toes, hands, and fingers
Oral lesions are painful vesicles that can occur anywhere in the mouth

A

Hand-foot-mouth disease

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9
Q

Acute Lymphonodular pharyngitis

A

Hyperplastic lymphoid tissue of the soft palate or tonsillar pillars appears as yellowish or dark pink nodules
Last several days to 2 weeks; usually no treatment

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10
Q

Other viral infections that may have oral manifestations

A

Measles

Mumps

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11
Q

Measles

A

Highly contagious disease causing systemic symptons and a skin rash
Koplik spots, small erythematous macules may occur in oral cavity

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12
Q

Caused by a type of virus called a paramyxovirus

A

Measles

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13
Q

Mumps

A

Viral infection of the salivary glands

Most commonly causes bilateral swelling of the parotid glands

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14
Q

How HIV is transmitted

A

Sexual contact
Contact with infected blood and blood products
Infected mothers to their infants

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15
Q

Infects cells of the immune system, particulary CD4 T-helper lymphocytes

A

HIV

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16
Q

This type of lymphocyte participates in cell-mediated immunity and in regulating the immune response

A

CD4 T-helper lymphocyte

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17
Q

The diagnosis of AIDS

A

HIV infections with severe CD4 lymphocyte depletion

Fewer than 200 CD4 lymphocytes per microfilter of blood

18
Q

Normal level of CD4 lymphocyte

A

between 550 and 1000

19
Q

What are the two antibody tests used to determine whether a person is infected with HIV

A

ELISA (enzyme-linked immunosorbent assay) is used first

When result of the test is positive twice, it is followed by the Western blot test

20
Q

Initial infection of AIDS may be

21
Q

AIDS-related complex is the occurrence of several signs and symptons together; what are they?

A

Oral candidiasis
Fatigue
Weight loss
Lymphadenopathy

22
Q

When do antibodies to HIV usually begin to become detectable

A

About 6 weeks after infection

23
Q

Window of infectivity

A

In some people, antibodies may not be detectable for 6 months or up to a year or longer

24
Q

Polymerase chain reaction (PCR)

A

Used to measure the amount of HIV circulating in serum

The measured amount is the viral load

25
Management of AIDS
Combinations of antiretroviral drugs and drugs used to treat opportunistic infections
26
Why do oral lesions develop with AIDS
Because of the deficiency of T-helper cells | These include opportunistic infections, tumors, and autoimmune-like diseases
27
Oral candidiasis (Thrush)
Treatment: Antifungal meds | In HIV positive pts, it generally signals the beginning of progressively severe immunodeficiency
28
Herpes simplex infection (AIDS)
An ulceration resulting from herpes simplex that has been present for more than 1 month "meets criteria for the diagnosis of AIDS"
29
Herpes Zoster (AIDS)
Generally follows the usual pattern when it occurs in a person who is HIV positive Lesions follow branches of the trigeminal nerve It is a sign of developing immunodeficency
30
Hairy leukoplakia (AIDS)
Caused by Epstein-Barr virus A predictor of AIDS in HIV-positive individuals Chronic tongue chewing and hyperplastic candidiasis can produce similar lesions
31
HPV (AIDS)
Assocaited with HIV infection May have normal color to be erythematous May be assocaited with antiretoviral treatment
32
An opprotunistic neoplasm that may occur in patients with HIV infection
Kaposi Sarcoma
33
Kaposi sarcoma
Most commonly on the palate and gingiva | Most associated with HIV positive pts with cancer
34
A malignant tumor that may occur in association with HIV infection
Lymphoma
35
Lymphoma
Appears as a nonulcerated, necrotic, or ulcerated mass | May be surfaced by ulcerated or normal-colored erythematous mucosa
36
Gingival and perio disease (HIV)
Unusual forms of gingival and periodontal diseases may develop in patients with HIV * Linear gingival erythema (LGE) * Necrotizing ulcerative periodontitis (NUP)
37
Three characteristics of Linear Gingival Erythema
Spontanous bleeding Punctate or petechiae-like lesions on attached gingiva and aveolar mucosa A bandlike erythema of the gingiva that goes not respond to therapy *Occurs independently of oral hygiene
38
Necrotizing Ulcerative periodontitits (NUP)
Intense erythema and extremely rapid bone loss Necrotizing stomatitis -Extensive focal areas of bone loss along with features of NUP
39
Treatment of LGE and NUP
``` Scaling Root planing Soft tissue curettage Intrasulcular lavage CHX mouth rinse Systemic metronidazole ```
40
Spontaneous gingival bleeding
A decrease in platelets may occasionally be seen in pts with HIV May be due to an autoimmune type of thrombocytopenic purpura
41
Aphthous ulcers (HIV)
Increase in the number of these ulcers in patients with HIV infection Resembling major aphthous ulcers appear as deep, persistent, painful ulcers Respond to steroids
42
Salivary gland disease
Bilateral parotid gland enlargement may occur in patients who are HIV positive