Chapter 52 Antidiabetics Flashcards Preview

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Flashcards in Chapter 52 Antidiabetics Deck (33):
0

Dx resulting from deficient glucose metabolism

Diabetes mellitus

1

Protein secreted from the beta cells of the pancreas

Insulin

2

Type of diabetes with no beta cell function

Type I

3

Type of diabetes with some beta cell function

Type 2

4

Diabetic acidosis

Ketoacidosis

5

Tissue atrophy

Lipodystrophy

6

Increased thirst

Polydipsia

7

Increased hunger

Polyphagia

8

Hyperglycemia on awakening

Dawn phenomenon

9

Intermediate acting insulin
NPH insulin
Lispro insulin

NPH insulin agitate because cloudy

10

Tissue atrophy

Lipodystrophy

11

Oral hypoglycemic drug group

Sulfonylureas

12

Hyperglycemic hormone that stimulates glucogenolysis

Glucagon

13

Rapid acting insulin
NPH INSULIN
Lispro

Lispro

14

Signs and symptoms of insulin shock (hypoglycemic reaction)

Nervousness
Tremors
Cold and clammy skin
Slurred speech
Headache
Excessive perspiration

15

Drugs that may cause hyperglycemia

Epinephrine
Hydrochlororothiazide
Prednisone

16

What is only type of insulin that may be given IV
Lantus
NPH
regular

Regular

17

Clinical manifestations seen with diabetic ketoacidosis (hyperglycemia)

Dry mucous membranes
Fruity breath odor
Kussmaul respirations
Polyuria
Thirst

18

Patient has type 1 diabetes. Which med should the patient not use to control his diabetes
Apidra
Humalog
Novolog
Tolinase

Tolinase because first generation intermediate acting oral antidiabetic agent

19

When giving both NPH and regular insulin at same time, which is drawn into syringe first

Regular

20

Name some actions to develop for site rotation pattern

Choose an injection for one week
Inject insulin each day at the injection site at 1.5 inches apart
With two daily injection times, use the right side in the morning and the left side in the evening

21

How long after NPH is given for insulin to peak
1–2 hours
2-6 hours
6-12 hours

6-12 hours

22

Lantus which is a long acting insulin, which statements best describe it

Given in evening
It is available in a 3-ml cartridge insulin pen
Some patients complain of pain at the injection site

23

What is a method to determine if patient has developed an allergy to insulin

Skin test with different insulin preparations

24

What is an action of an oral hypoglycemic agent

It increases number of insulin cell receptors

25

How is prandin different than insulin

Can only be used only when the is some beta cell function

26

How does precose work

Inhibiting digestive enzymes in small intestine which release glucose from the complex carbs in diet

27

How does the group of thiazolidinedione group of nonsulfonylureas work

Increase insulin sensitivity for improving glucose control
Actos is a drug in this group

28

Patients taking actos and Avandia should be monitored with what lab test
Bun
Cardiac enzymes
Liver enzymes

Liver enzymes should be evaluated and monitored throughout treatment with thiazolidinediones

29

How do ginseng and garlic affect insulin or antidiabetic drugs

Lower blood glucose level thus causing a hypoglycemic effect

30

What are recommended guidelines for use of oral antidiabetics

Fasting blood sugar less than 200
Normal renal and hepatic function
Onset at age 40 years or older

31

Which drugs or categories of drugs will interact with sulfonylurea

Anticoagulant
Anticonvulsant
Aspirin
Sulfonamides

32

Contraindications for use of oral antidiabetic drugs

Breastfeeding
Pregnancy
Renal dysfunction
Severe infection