Chemical/Biological/Nuclear/Radiological warfare Flashcards Preview

Pharmacology > Chemical/Biological/Nuclear/Radiological warfare > Flashcards

Flashcards in Chemical/Biological/Nuclear/Radiological warfare Deck (47):
1

Schedule 1 chemical agents are used how

few legitimate uses

2

Schedule 2 chemical agents are used how

small scale use

3

Schedule 3 chemical agents are used how

large scale industrial uses

4

Name three blistering agents

Mustard

Lewisite

Phosgene oxime

5

The chemical agent mustarg smells like

Garlic, onions, mustard, or odorless

6

How to treat mustard exposure

give milk

*don't induce vomiting

7

Mustard has what effect on eyes

blindess up to 10 days

8

Lewisite smells like

geraniums (flowers)

9

Lewisite contains

arsenic

10

Lewisite may cause

hypotension

11

Phosgene oxime causes skin to have

red ring hives

12

Phosgene oxime causes what respiratory effect

pulmonary edema

13

Phosgene oxime should be treated with

water (flush 5-10 minutes)

14

Name five blood agents that affect the body by inhibiting the use and transfer of oxygen

Arsine
Cyanide
Hydrogen Cyanide
Cyanogen Chloride
Sodium/Potassium cyanide

15

Cyanide smells like

bitter almond or no scent at all

16

What is the MOA of cyanide poisoning

cyanide ions halts cellular respiration by inhibiting cytochrome C oxidase preventing cells from ultilizing oxygen

17

What are CV signs of cyanide toxicity

brady and HTN>>hypotension with Tachycardia>>brady and Hypotension

*expect falsely elevated pulse oximetry

18

What skin color is noted in someone with cyanide toxicity

cherry red

19

What three drugs are used to tx cyanide toxicity

Amyl nitrate

Sodium nitrite

Sodium thiosulfate

20

Arsine causes damage to

RBC

21

Arsine has what odor

garlic

22

Arsine is spread through

air

23

Name two Choking agents

Chlorine

Phosgene

*cause pulmonary edema and respiratory failure

24

What does chlorine smell like

bleach

25

Phosgene smells like

hay, green corn

26

How long could it take for phosgene symptoms to occur

48 hours

27

Two classes of nerve agents include

carbamates

organophosphates

28

what are three carbamates

physostigmine, neostigmine, and pyridostigmine

29

What is an example of organophospates

irreversible pesticides

30

G-series nerve gases include

Tabun
Sarin
Soman

31

V-series nerve gases include

VX

32

Nerve agents work by

inhibiting cholinesterase>>respiratory paralysis

33

What are early symptoms of nerve agent toxicity

Muscarinic effects
bronchospasm, bradycardia, miosis, SLUDGE

34

What are late symptoms of nerve agent toxicity

Nicotinic effects
Motor>>flaccid paralysis>apnea>death

35

What are three antidotes to nerve agent toxicity

Atropine

2-PAM

Benzodiazepines

36

If antidotes for nerve agent given too quickly, what can happen

Resp/cardiac arrest

37

What agent is given as a prophalactic to nerve agent exposure

pyridostigmine

38

Treatment of nerve gas with atropine can lead to Central anticholineric syndrome which manifests how?

hyperthermia (from impaired sweating)
dry mouth
flushed skin (red)
mydriasis
delirium

39

What is the antidote of atropine

physostigmine

40

Name four biologic conditions that cause injury in warfare

anthrax
variola
viral hemorrhagic fever
plague

41

Is inhalational anthrax infectious

no

*patient goes thru period of improvement>>>sudden severe symptoms

42

Small pox is caused by a virus and is characterized by

lung infection>>bloodstream>>to surface>>RASH

43

Ebola is known as

Viral hemorrhagic fever

44

Name three toxins

Ricin
Botulism
Saxitorxin

45

What is the most deadly toxin known

Botulism

46

Botulism works by

binding to presynaptic cholinergic receptors>>>decreaed Ach

*flaccid paralysis

47

Saxitoxin effects

sodium channels via blockage


*death within minutes with inhalation