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Cielená Liečba Flashcards

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1
Q

EGFR -HER1 inhibítory MPL

A

Ceruximab

Panitumumab

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2
Q

EGFR -HER 1 TKI

A
  1. generace=gefitinib, erlotinib
  2. g= afatinib
  3. g= osimertinib
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3
Q

HER 2 inhibítory MPL/TKI

A

MPL- trastuzumab
Pertuzumab
TKI - lapatinib
Neratinib

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4
Q

ALK inhibítory- nsclc

A
  1. g- crizotinib
  2. g- ceritinib, alectinib, brigatinib
  3. g- lorlatinib
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5
Q

Vegf/vegfr

MPL

A

Vegf-bevacizumab, aflibercept

Vegfr- ramucirumab

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6
Q

TKI vegfr

A

Multikinazove inhibítory

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7
Q

mTOR INHIBÍTORY

A

Temsirolimus, everolimus

Rapamycin

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8
Q

Braf-mek inhibítory

A

Braf- dabra/vemura/encoraFENIB

MEK- trame/binimeTINIB

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9
Q

PARP inhibitor

A

Olaparib
Rukaparib
Niraparib

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10
Q

Cdk4/6

A

Palbociklib
Ribociklib
Abemaciklib

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11
Q

Inhibítory proteazomu

A

Bortezomid
Ixazomid
Calfilzomid

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