Cirrhosis Flashcards Preview

Hugh's MD2 Core Conditions and Presentations > Cirrhosis > Flashcards

Flashcards in Cirrhosis Deck (15):
1

What is the pattern of fibrosis in viral hepatitis cirrhosis?

Macronodular

1

What are the best indicators of liver function (blood test results)?

Serum albumin <28g/L in cirrhosis

Prothrombin time >6s above normal in cirrhosis

2

What is the 5 year survival rate for patients with cirrhosis?

50%

2

What might the cause of acute onset ascite be in patient with cirrhosis?

High dietary Na

The development of hepatocellular carcinoma

Splanchnic vein thrombosis

3

What must be considered when percussing for ascites?

When turning the patient on their side, avoid the side where organomegaly is present

4

What are the 12 causes of cirrhosis?

Alcohol steatohepatitis

Viral hepatitis (Hep B and C)

NAFLD

Primary billiary cirrhosis

Primary sclerosing cholangitis

Autoimmune hepatitis

Haemochromatosis

Wilson's Disease

Cardiac cirrhosis (hepatic vein congestion)

Idiopathic

Drugs (eg methotrexate)

Cystic fibrosis

5

What are the 5 criteria used in the modified Child's-Pugh classicification?

Ascites

Encephalopathy

Bilirubin

Albumin

Prothrombin time

8

What is the pattern of fibrosis in alcoholic hepatitis cirrhosis?

Micronodular

9

What is the most common cause of cirrhosis in the west?

Alcoholic steatohepatitis

10

What should be measured in young cirrhotic patients?

Copper and serum alpha-anti-trypsin

11

What is the most common cause of cirrhosis worldwide?

Viral

12

What might be found on LFTs in a patient with hepatocellular carcinoma?

Raised ALP

13

What Ix can be performed for cirrhosis?

Ultrasound

CT scan

Endoscopy - varices, portal hypertension

MRI - useful for diagnosis of benign tumours

14

What are some causes of a massive liver?

Metastases

Alcoholic liver disease with fatty infiltration

Myeloproliferative disease

Right heart failure

Hepatocellular cancer

15

What are some precipitants for hepatic encephalopathy in a patient with cirrhosis?

Progressive liver injury

Alcohol binge

Acute viral hepatitis

Upper GI bleeding

Hepatocellular carcinoma

Infection

Increased portosystemic shunts (eg new TIPSS)

Zinc deficiency

Dehydration

Constipation

Drugs (eg opiates)

Non-compliance