What is the pattern of fibrosis in viral hepatitis cirrhosis?
What are the best indicators of liver function (blood test results)?
Serum albumin <28g/L in cirrhosis
Prothrombin time >6s above normal in cirrhosis
What is the 5 year survival rate for patients with cirrhosis?
What might the cause of acute onset ascite be in patient with cirrhosis?
High dietary Na
The development of hepatocellular carcinoma
Splanchnic vein thrombosis
What must be considered when percussing for ascites?
When turning the patient on their side, avoid the side where organomegaly is present
What are the 12 causes of cirrhosis?
Viral hepatitis (Hep B and C)
Primary billiary cirrhosis
Primary sclerosing cholangitis
Cardiac cirrhosis (hepatic vein congestion)
Drugs (eg methotrexate)
What are the 5 criteria used in the modified Child's-Pugh classicification?
What is the pattern of fibrosis in alcoholic hepatitis cirrhosis?
What is the most common cause of cirrhosis in the west?
What should be measured in young cirrhotic patients?
Copper and serum alpha-anti-trypsin
What is the most common cause of cirrhosis worldwide?
What might be found on LFTs in a patient with hepatocellular carcinoma?
What Ix can be performed for cirrhosis?
Endoscopy - varices, portal hypertension
MRI - useful for diagnosis of benign tumours
What are some causes of a massive liver?
Alcoholic liver disease with fatty infiltration
Right heart failure
What are some precipitants for hepatic encephalopathy in a patient with cirrhosis?
Progressive liver injury
Acute viral hepatitis
Upper GI bleeding
Increased portosystemic shunts (eg new TIPSS)
Drugs (eg opiates)