Class 2

Question 1

Apoptosis

Answer 1

programmed cell death

Question 2

Necrosis

Answer 2

exogenously induced cell death

Question 3

Most common necrosis

Answer 3

Coagulative

Question 4

Coagulative necrosis occurs when

Answer 4

cell proteins altered

Question 5

Ex. of coagulative necrosis

Answer 5

Heart attack

Question 6

Coagulative necrosis typically occurs in

Answer 6

solid internal organs

Question 7

What occurs during Liquefactive necrosis

Answer 7

Dead cells liquify

Question 8

What happens to tissues from liquefactive necrosis

Answer 8

Become soft

Question 9

Where liquefactive necrosis occurs most?

Answer 9

Brain

Question 10

Where caseous necrosis typically found

Answer 10

In tuberculosis

Question 11

What happens to tissue from caseous necrosis

Answer 11

Become cheesy and yellow

Question 12

What Fat necrosis causes

Answer 12

Form of liquefactive necrosis limited to fat tissue

Question 13

Gangrene

Answer 13

dead tissue

Question 14

lysis means

Answer 14

Dissolution of cell

Question 15

What form of cell death is Apoptosis

Answer 15

Active form, highly regulated

Question 16

Inflammation is

Answer 16

Response to tissue injury

Question 17

Pathogenesis of inflammation involves how many steps

Answer 17

4

Question 18

Pathogenesis of inflammation step 1:

Answer 18

Changes in circulation of blood

Question 19

Pathogenesis of inflammation step 2

Answer 19

Changes in vessel wall permeability

Question 20

Pathogenesis of inflammation step 3

Answer 20

Release of soluable mediators of inflammation

Question 21

Pathogenesis of inflammation step 4

Answer 21

Cellular events – leukocyte emigration/Phagocytosis

Question 22

Histamine released from

Answer 22

Platelets and mast cells

Question 23

Histamine increases?

Answer 23

Blood vessel permeability

Question 24

Bradykinin is what?

Answer 24

Plasma protein

Question 25

Bradykinin does what?

Answer 25

similar to histamine/slower/incites pain

Question 26

Complement System is

Answer 26

Group of plasma proteins from liver/ inactive

Question 27

Activation of complement system leads to

Answer 27

Biologically active fragments, intermediate complexes, membrane attack complex

Question 28

Opsonization

Answer 28

Phagocytosis of bacteria

Question 29

Anaphalaxis

Answer 29

histamine release w/ increased permeability

Question 30

Chemotaxis

Answer 30

Migration of leukocytes

Question 31

Cell lysis happens through

Answer 31

MAC

Question 32

Arachidonic Acid (AA) Derivatives derived from

Answer 32

Phospholipids of cell membranes

Question 33

AA metabolized through

Answer 33

Lipoxygenase pathway Cyclooxygenase pathway

Question 34

Leukotrienes

Answer 34

Promote chemotaxis

Question 35

Lipoxins

Answer 35

Inhibit chemotaxis

Question 36

Prostaglandins

Answer 36

Cause vasodilation

Question 37

Prostacyclin

Answer 37

counters thromboxane

Question 38

Thromboxane

Answer 38

Platelet aggregation

Question 39

Emigration of leukocytes increases? how long?

Answer 39

Permeability of vessel wall/ up to several hours

Question 40

As scavengers, PMNs do what?

Answer 40

Uptake cellular debris/bacteria

Question 40

Phagocytosis causes PMNs to

Answer 40

Lose mobility, act as scavengers

Question 41

Neutrophils (PMN) are the

Answer 41

Most numerous circulating WBCs

Question 42

Eosinophils are prominent in

Answer 42

Allergic reactions

Question 43

Basophils are prominent in

Answer 43

Allergic reactions mediated by IgE

Question 44

Macrophages appear after how long?

Answer 44

3-4 days after onset

Question 45

Macrophages are

Answer 45

Phagocytic and bactericidal

Question 46

Platelets

Answer 46

fragments of cytoplasm from megakaryocytes

Question 47

Transudate

Answer 47

Fluid that passes through membrane

Question 48

Exudate

Answer 48

Fluid released from body

Question 49

Chemotaxis moves WBC's...

Answer 49

Up and along concentration gradient