Class 4 Flashcards

(53 cards)

1
Q

Immunity

A

Protection from diseases

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2
Q

Natural immunity

A

Born with it

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3
Q

Acquired immunity

A

Develop with exposure

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4
Q

Primitive natural immunity

A

nonspecific form of immunity

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5
Q

Inherited natural immunity

A

Not dependent on previous exposure

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6
Q

Natural immunity includes which cell type?

A

NK cells

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7
Q

Properdin

A

Plasma protein activate alternate complement pathway

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8
Q

Lysozyme

A

protein in tears, nasal secretion

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9
Q

Acquired immunity based on

A

Responses stimulated by antigens

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10
Q

Antigen

A

chemical substance elicit immune response

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11
Q

immunocompetance

A

ability to mount an appropriate immune response

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12
Q

Lymphocytes

A

bone marrow stem cells giving rise to two cell types

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13
Q

Lymphocytes derive into

A

T-lymphocytes, B-lymphocytes

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14
Q

T lymphocytes mature in?

A

thymus

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15
Q

B lymphocytes mature in?

A

Bone marrow

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16
Q

Primary lymphoid organs

A

bone marrow and thymus

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17
Q

Secondary lymphoid organs

A

spleen and lymph nodes

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18
Q

NK Cells functions

A

kill tumor and foreign cells

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19
Q

T Helper (CD4+) Cells funtions

A

help B cells produce antibodies
secrete cytokines

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20
Q

T suppressor (CD8+) Cell function

A

Supress unwanted antibody prod.

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21
Q

Ratio of CD4+/CD8+ ?

A

2:1

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22
Q

Antibodies are

A

Proteins secreted by plasma cells, help fight antigens

22
Q

B lymphocyte functions

A

Differentiate into antibody

23
Q

Plasma Cells synthesize?

A

Contain ribosomes and RER - antibody synthesis

24
IgM
Largest immunoglobin, first to appear
25
IgG
Smallest, most abundant
26
IgA
In mucosal secretions
27
IgE
Mediates allergic reactions Secreted in tissues/ attached to mast cells
28
IgD
Exclusive to B cells
29
Antibody production begins with
contact between antigen and immune system cells
30
antigen-presenting cells (APC) are
B-cells internalizing antigen presenting to T-Cells
31
Antibody production requires support of
T Helper Cells
32
T-Helper cell produces
Cytokines
33
Cytokynes transform B-cell into
Plasma cell
34
Plasma cell produces
Antibodies
35
AgAb complexes bind on RBC's cause
Agglutination
36
Hay Fever is Type ?
Type 1 hypersensitivity
37
Atopic dermatitis (eczema) type?
Type 1 hypersensitivity
38
Bronchial asthma type?
Type 1 hypersensitivity
39
Anaphylactic shock type?
Type 1 hypersensitivity
40
Type 2 mediated by
IgG or IgM
41
Goodpastures syndrome type?
Type 2 hypersensitivity
42
Hemolytic anemia type?
Type 2 hypersensitivity
43
Graves disease type?
Type 2 hypersensitivity
44
Myasthenia Gravis type?
Type 2
45
SLE and Post-streptococcal type
Type 3
46
Polyarteritis Nodosa type?
Type 3
47
Type 4 hypersensitivity causes
Aggregate and form granulomas at injury site
48
Transplantation is?
Solid tissue transplant
49
Autograft
Self donor
50
Isograft
Identical twins
51
Homograft
Same species/not identicalX
52
Xenograft
Transplant b/w species