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Class/indication Flashcards

1
Q

Balsalazide

A

Maintenance or acute ulcerative colitis

Amino salicylate

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2
Q

Mesalazine

A 
Acute or maintenance of IBD
Amino salicylate (rectal and oral)
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3
Q

Olsalazine

A

Acute or maintenance of mild ulcerative colitis

Amino salicylate

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4
Q

Sulfasalazine

A

Amino salicylate

Mild to severe IBD and active rheumatoid arthritis

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5
Q

Beclometasone

A

Corticosteroid
Adjunct to amino salicylate in ulcerative colitis

Prophylaxis of asthma
Allergic and vasomotor rhinitis

Management of oral ulceration

0.025% is potent for severe inflammatory skin disorders and psoriasis

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6
Q

Budesonide

A

Corticosteroid - glucocorticoid
IBD (including foam for ulcerative colitis affecting sigmoid colon and rectum)
Autoimmune hepatitis

Prophylaxis of mild to moderate asthma

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7
Q

Vedolizumab

A

Anti lymphocyte monoclonal antibody

IBD unresponsive to conventional or TNF inhibitor

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8
Q

Eluxadoline

A

Antidiarrhoeal antipropulsive

IBS with diarrhoea

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9
Q

Peppermint oil

A

Antispasmodic

Abdominal colic and distention particularly in IBS

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10
Q

Linaclotide

A

Guanylate cyclase c receptor agonist laxative

IBS with constipation

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11
Q

Teduglutide

A

GLP-2 analogue

Short bowel syndrome

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12
Q

Citric acid with magnesium carbonate (citrameg)

A

Osmotic laxative

Bowel evacuation

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13
Q

Macrogol 3350

A

Osmotic laxative

Bowel cleansing

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14
Q

Magnesium citrate with sodium picosulfate

A 
Stimulant laxative
Bowel evacuation (day be for)
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15
Q

Isphagula husk

A

Constipation

Bulk forming laxative from 1 month

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16
Q

Methyl cellulose

A

Bulk forming laxative

Contipation and diarrhoea in adults

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17
Q

Stericula

A

Bulk forming laxative

Contipation from 6 years old

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18
Q

Lubiprostone

A

Chloride channel agonist

Chronic idiopathic constipation

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19
Q

Lactulose

A

Osmotic laxative with 48 hours to act
Contipation from 1 month
Hepatic encephalopathy

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20
Q

Macrogol 3350

A

Osmotic laxative onset in 24 - 48 hours
Chchronic constipation in adults
Laxido and movicol (with chlorides/bicarbonate) also for foecal impaction

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21
Q

Magnesium hydroxide

A

Constipation in adults

Osmotic laxative

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22
Q

Prucalopride

A

Selective serotonin agonist

Chronic constipation

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23
Q

Docusate

A

Stimulant and softening laxative acting in 1-2 days or 20 minuted (anal)
Chronic constipation

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24
Q

Bisacodyl

A

Stimulant laxative acting in 10 - 12 hours or 20 - 60 minutes
Contipation
bowel clearance

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25
Senna
Stimulant laxative acting in 8 - 12 hours | Constipation
26
Sodium picosulfate
Stimulant laxatives with onset in 6 - 12 hours | Constipation
27
Methylnaltrexone
Opioid induced constipation | Opioid receptor antagonist acts within 30 - 60 mins
28
Naloxegol
Opioid induced constipation | Opioid receptor antagonist
29
Loperamide
Diarrhoea Foecal incontinence Bowel colic
30
Racecadotril
Diarrhoea | Enkephalinase inhibitor
31
Co phenotrope
Diarrhoea and control of consistency following stoma | Antipropulsive
32
Koalin
Diarrhoea | Intestinal absorbent
33
Sucralfate
Gastritis, ulceration | Chelate
34
Cimetidine
Ulceration, oesophagitis, reduce degradation of pancreatic enzyme supplementation H2 receptor antagonist
35
Esomeprazole
Proton pump inhibitor | Ulcers, GORD, Zollinger Ellison, h pylori
36
Lansoprazole
Proton pump inhibitor | H pylori, ulcers, Zollinger Ellison, GORD, oesophagitis, acid related dyspepsia
37
Dicycloverine
Antimuscarinic | Smooth muscle spasm
38
Hyoscine
Antimuscarinic | Smooth muscle spasm, IBS, Respiratory secretions, bowel colic
39
Propantheline
Antimuscarinic | Smooth muscle spasm and anuresis in adults
40
Alverine
Antispasmodics | Smooth muscle spasm and dysmenorrhoea
41
Mebeverine
Antispasmodic | IBS or smooth muscle spasm
42
Chonedeoxycholic acid
``` Cerebrotenidinous xanthomatosis (inborn errors of bile acid synthesis). Bile acid ```
43
Cholic acid
Inborn errors of bile acid synthesis | Bile acid
44
Obeticholic acid
Bile acid | Biliary cholangitis
45
Ursodeoxycholic acid
Bile acid | Dissolution of gallstones and biliary cirrhosis
46
Terlipressin
Vasopressin analogue | Bleeding from oesophageal varices
47
Naltrexone with bupropion
Adjunct in obesity with dietary measures when bmi above 30 or 27 with Co morbidity SNRI
48
Orlistat
Lipase inhibitor | Adjunct in obesity
49
Disopyramide
Ventricular and supra ventricular arrythmias including after MI. maintain sinus rythmn after cardioversion Class 1a anti arrythmic
50
Lidocaine
Class 1b anti arrythmic and anaesthetic Cardiopulmonary resuscitation (if amiodarone unavailable) Ventricular arrythmias Dental practice Relief of pain in oral regions
51
Flecainide
Class 1c anti arrythmic | Supra ventricular and ventricular arrythmias
52
Propafenone
Class 1c anti arrythmic | Ventricular and paroxysmal supra ventricular arrythmias
53
Amiodarone
Class 3 anti arrythmic | Arrythmias particularly where other measures ineffective
54
Dronedarone
Class 3 anti arrythmic | Maintenance of sinus rythmn after cardioversion (paroxysmal or persistent)
55
Adenosine
Anti arrythmic | Rapid reversion to sinus rythmn in paroxysmal supra ventricular tachycardia
56
Sotalol
Non selective beta blocker Ventricular tachyarrythmia Maintenance of sinus rythmn after cardioversion of AF or flutter
57
Digoxin
Cardiac glycoside Heart failure rapid digitalisation
58
Tranexamic acid
``` Antifibrinolytic Local and general fibrinolysis Menorrhagia Hereditary angioedema Epstaxis Prevention and treatment of significant haemorrhage following trauma ```
59
Emicizumab
Haemostatic | Prophylaxis of haemorrhage in haemophilia A
60
Dried prothrombin complex
Coagulation proteins Treatment and prophylaxis of haemorrhage in factor deficiency Major bleeding with warfarin following phytomenadione
61
Idarucizumab
Antidote/chaltor for dabigatran
62
Aspirin
Antiplatelet Secondary prevention of cvd (75mg) ACS (300mg) Suspected TIA (300mg) TIA or stroke (75mg daily) Atrial fibrillation following disabling stroke (300mg daily for 14 days) Following disabling stroke when recieveing anticoagulation for prosthetic heart valve and risk of haemorrhagic transformation (300mg daily) Following coronary by pass (75 - 300mg daily) Mild to moderate pain (300-900mg every 4 to 6 hours. Max 4g)
63
Clopidogrel
Antiplatelet Prevention of artherothrombotic events in percutaneous coronary intervention (loading 300/600 mg previous to procedure) TIA or stroke if aspirin hypersensitive Prevention of artherothrombotic events in peripheral arterial disease or within 35 days of MI or 6 months of stroke. After NSTEMI/STEMI Atrial fibrillation where warfarin unsuitable
64
Dipyridamole
Secondary prevention fo stroke or thromboembolism with prosthetic valve antiplatelet
65
Apixaban
Direct factor xa inhibitor 2.5mg BD following knee (10-14 days) or hip (32 - 38 days) replacement started 12 - 24 hours after surgery 10mg BD for 7 days after VTE then maintenance 5mg BD 2.5mg BD for recurrent after 6 months above. 5mg BD in AF
66
Edoxaban
Direct reversible inhibitor of factor xa | 30 - 60mg daily depending on weight below 61kg for AF and following 5 days of parenteral in VTE
67
Fondaparinux
``` Factor X inhibitor Prophylaxis of VTE if major/othro/hip/leg/abdominal surgery Superficial vein thrombosis ACS Treatment of VTE ```
68
Rivaroxaban
Factor xa direct inhibitor 10mg daily for 2 (knee) to 5 (hip) weeks in replacement surgery started 6 - 10 hours after surgery Treatment of VTE - initially 15mg BD for 21 days then 20mg daily AF Following ACS with elevated biomarkers
69
Danaparoid
Heparinoid Prevention of dvt in general or ortho surgery Thromboembolic disease with history of heparin induced thrombocytopenia
70
Dalteparin
``` LMWH Treatment of VTE Unstable coronary artery disease (different doses depending on risks) Prophylaxis of dvt ```
71
Enoxaparin
LMWH Treatment of VTE, STEMI Unstable angina and NSTEMI. Prevention of clotting in extracorporeal circuits
72
Tinzaparin
LMWH Treatment of VTE Prophylaxis of dvt Prevention of clotting in extracorporeal circuits
73
Argatroban
Thrombin inhibitor Anticoagulation in patients with heparin induced thrombocytopenia (different doses if pci, cardiac surgery, warfarin or critically ill)
74
Bivalirudin
Thrombin inhibitor | Unstable angina, NSTEMI and anticoagulation if having in intervention
75
Dabigatran
Thrombin inhibitor 110mg 1-4 hours after surgery, then 220mg daily (or 150mg with amiodaron/Verapamil) Prophylaxis of VTE following knee (9 days after) or hip (27 - 34 days after) replacement 75mg then 150mg in over 75yo Treatment of prophylaxis of recurrent following parenteral anticoagulant AF
76
Urokinase
Tissue plasminogen activators VTE Occlusive peripheral artery disease Occluded central venous catheter or haemodialysis shunts blocked by fibrin clots
77
Acenocoumarol
Vitamin k antagonists | Prophylaxis of embolization in rheumatic heart disease and atrial fibrillation, inserted prosthetic heart valve, TIA
78
Phenindione
Prophylaxis of embolization in rheumatic heart disease and atrial fibrillation, inserted prosthetic heart valve Vitamin k antagonists
79
Warfarin
Vitamin k antagonists | Prophylaxis of embolization in rheumatic heart disease and atrial fibrillation, inserted prosthetic heart valve and TIA
80
Clonidine
Centrally acting antihypertensive Hypertension Prevention of recurrent migraine, vascular headache, menopausal symptoms (flushing, vasomotor)
81
Methyldopa
Centrally acting antihypertensive
82
Moxonidine
Centrally acting antihypertensive
83
Timolol
``` Non selective beta blocker Hypertension Angina Prophylaxis after MI Migraine prophylaxis ``` Reduction of Intra ocular pressure in open angle glaucoma
84
Acebutolol
Selective beta blocker Hypertension Angina Arrythmias
85
Atenolol
``` Selective beta blocker Hypertension Angina Arrythmias Migraine prophylaxis Early intervention within 12 hours of MI ```
86
Bisoprolol
Selective beta blocker Hypertension Angina Adjunct in heart failure
87
Celiprolol
Selective beta blocker | Mild to mod hypertension
88
Co-tenidone
Atenolol with chlortalidone (thiazide)
89
Esmolol
Selective beta blocker Supra ventricular arrythmia Tachycardia and hypertension in peri op
90
Metoprolol
``` Selective beta blocker Hypertension Angina Arrythmias (including in surgery) Migraine prophylaxis Early intervention within 12 hours of the mi Hyperthyroidism ```
91
Nebivilol
Selective beta blocker Hypertension Adjunct in mild to mod heart failure
92
Amlodipine
Calcium channel blocker Prophylaxis of angina Hypertension Initially 5mg to max 10mg.
93
Diltiazem
Calcium channel blocker Prophylaxis and treatment of angina Mild to moderate hypertension Adizem/Angitil/dilcardia/dilzem SR, tildiem retard BD ~ 90 - 120mg up to 180mg Adizem/angitil/dilzem/viazem XL, slozem, zemtard, tildiem LA OD ~ 180 - 240mg up to 300 - 360mg.
94
Felodipine
Calcium channel blocker Prophylaxis of angina Hypertension
95
Lacidipine
Calcium channel blocker (dihydropyridine) | Hypertension
96
Lercanidipine
Dihydropyridine calcium channel blocker | Mild to moderate hypertension
97
Nicardipine
Dihydropyridine calcium channel blocker Prophylaxis of angina Mild to moderate hypertension Life threatening hypertension (incl neonates and pregnancy)
98
Nifedipine
``` Dihydropyridine calcium channel blocker Raynauds syndrome Kawasaki disease Hiccup in palliative care Postponement of premature labour ``` Angina prophylaxis Hypertension Adalat capsules - tds (5mg - 20mg) Adalat LA, Adipine XL, coracten XL, Valni XL, Fortipine LA 40 OD (30mg to 90mg) Adipine MR, coracten SR, nifedipress Mr, tensipine MR BD (10mg to 40mg)
99
Verapamil
Calcium channel blocker Treatment of supra ventricular arrythmias Paroxysmal tachyarrhythmia Prophylaxis of cluster headache Angina 240mg BD may be reduced to OD Hypertension 120mg then 240mg OD - 480mg divided Prophylaxis after MI where beta blockers inappropriate 360MG divided (securon only)
100
Bendroflumethiazide
Thiazide diuretic Oedema (5-10mg weekly-daily) Hypertension (2.5mg daily)
101
Co-amilozide
Amiloride and hydrochlorothiazide Hypertension Congestive heart failure Oedema and ascites
102
Indapamide
Thiazide like diuretic | Essential hypertension
103
Captopril
``` ACEIs Hypertension Heart failure Within 24 hours of MI Diabetic neuropathy ```
104
Enalopril
ACEIs Hypertension Heart failure Prevention of heart failure with left ventricular dysfunction
105
Lisinopril
``` ACEIs Hypertension Following MI Renal complications of diabetes Heart failure ```
106
Perindopril
ACEIs Hypertension Symptomatic heart failure Following MI
107
Ramipril
``` ACEIs Hypertension Symptomatic heart failure Following MI Prevention of cvd Neuropathy ```
108
Azilsartan
ARB Hypertension Hypertension with intravascular volume depletion
109
Candesartan
ARB Hypertension Hypertension with intravascular volume depletion Heart failure with impaired left ventricular function when ACEIs not tolerated
110
Irbesartan
ARB Hypertension Hypertension when recieveing haemodialysis Renal disease in diabetes
111
Losartan
ARB Diabetic neuropathy Chronic heart failure when ACEIs are unsuitable Hypertension Hypertension with intravascular volume depletion
112
Valsartan
ARB Hypertension Hypertension with intravascular volume depletion Heart failure when ACEIs or beta blockers are unsuitable MI with left ventricular dysfunction /failure
113
Aliskerin
Renin inhibitor | Essential hypertension
114
Hydralazine
Vasodilator antihypertensive Moderate to sever hypertension Heart failure Hypertensive emergency
115
Phenoxybenzamine
Peripheral vasodilator | Hypertension in phaeochromocytoma
116
Pentolamine
Peripheral vasodilator | Hypertensive episodes in phaeochromocytoma and its diagnosis
117
Guanethidine
Peripherally acting anti adrenergic | Hypertensive crisis
118
Sodium nitroprusside
Vasodilator antihypertensive Hypertensive emergency Hypotension in anaesthesia Acute or chronic heart failure
119
Selexipag
Antiplatelet | Pulmonary arterial hypertension
120
Iloprost
Cardiovascular prostoglandin | Idiopathic or familial pulmonary arterial hypertension
121
Ambrisentan
Endothelian receptor antagonists | Pulmonary arterial hypertension
122
Bosentan
Endothelian receptor antagonists Pulmonary arterial hypertension systemic sclerosis with ongoing digital ulcer disease
123
Riociguat
Guanylate cyclase stimulator | Chronic thromboembolic pulmonary hypertension
124
Dopamine
Ionotropic sympathomimetics | Cardiogenic shock
125
Midodrine
Vasoconstricting sympathomimetic | Severe orthostatic hypotension
126
Noradrenaline
Vasoconstricting sympathomimetic | Acute hypotension
127
Phenylephrine
Vasoconstricting sympathomimetic Acute hypotension Priapism associated with alprostadil Mydriasis (eye drops)
128
Eplernone
Aldosterone antagonist Adjunct in stable patients with LVEF under 40 with HF following MI. Adjunct in chronic HF with LVEF under 30.
129
Spironolactone
Aldosterone antagonist 25mg OD; Moderate to severe HF (to 50mg) Resistant hypertension ``` 100 - 400mg; Oedema, ascites Malignant ascites Nephrotic syndrome Oedema in CHF Primary hyperaldosteronism ```
130
Enoximone
Phosphodiesterase type 3 inhibitors | CHF where cardiac output reduced and filling pressures increased.
131
Colesevelam
``` Bile acid sequestrant Primary hypercholstrolemia (with or without statin and ezetimibe) ```
132
Colestyramine
Bile acid sequestrant Hyperlipidaemia Pruritis in biliary obstruction and cirrhosis Diarrhoea in chrons, ileal resection, vagotomy, diabetic vagal neuropathy and radiation Accelerated elimination of teriflunomide/leflunomide
133
Ezetimibe
Cholesterol absorption inhibitor | Hypercholstrolemia
134
Bezafibrate
Fibrate (lipid modifying drug) Hyperlipidaemia if statin not tolerated Severe hypertriglyceridaemia
135
Fenofibrate
Fibrate (lipid modifying drug) Hyperlipidaemia when statin not tolerated Severe hypertriglyceridaemia
136
Gemfiibrozil
Fibrate (lipid modifying drug) Hyperlipidaemia Hypertriglyceridaemia
137
Acipimox
Nicotinic. Acid derivative | Hyperlipidaemia not responding
138
Nicotinic acid
Lipid modifying drug | Adjunct to statin in dyslipidaemia or alone if not tolerated
139
Atorvastatin
High density statin from 20mg Hypercholstrolemia Primary/secondaey prevention of cvd
140
Fluvastatin
Medium intensity statin at 80mg Hypercholstrolemia Prevention of coronary events after percutaneous coronary intervention
141
Pravastatin
Low intensity statin Hypercholstrolemia Prevention of cvd events in previous MI or unstable angina. Reduction of hyperlipidaemia if recieveing immunosuppression
142
Rosuvastatin
High intensity statin at 10mg Hypercholstrolemia Prevention of cvd events
143
Simvastatin
High intensity statin at 80mg Hypercholstrolemia Prevention of cvd events in cvd or diabetes
144
Alirocumab
Lipid modifying drug | Hypercholstrolemia a nd dyslipidaemia
145
Evolocumab
Lipid modifying drug | Hypercholstrolemia /dyslipidaemia
146
Lomitapide
Lipid modifying drug | Hypercholstrolemia
147
Cangrelor
Antiplatelet | In combination with aspriirn for reduction of thrombotic events in coronary artery disease undergoing PCI
148
Abxiximab
Glycoprotein IIB/IIIA inhibitor - antithrombotic Prevention of ischemic complications when undergoing pci Short term prevention of MI with unstable angina scheduled for pci
149
Eptifibatide
Glycoprotein IIB/IIIA INHIBITOR - antithrombotic In combination with aspirin ad Unfractionated heparin for prevention of early MI with unstable angina or NSTEMI when chest pain within 24 hours.
150
Tirofiban
Glycoprotein IIB /IIIA inhibitor - antithrombotic In combination with Unfractionated heparin, aspirin and clopidogrel for prevention of early MI with unstable angina or NSTEMI when chest pain within 12 hours.
151
Ranolazine
Piperazine derivative | Adjunct for stable angina
152
Ivabradine
Selective sinus node if inhibitor Angina Mild to severe chronic heart failure
153
Nicorandil
Potassium channel opener | Prophylaxis and treatment of stable angina
154
Prasugrel
Antiplatelet | In combination with aspirin for preventing artherothrombotic events when undergoing pci
155
Ticagrelor
Antiplatelet In combination with aspirin for preventing artherothrombotic events with acs Alternative to clopidogrel undergoing pci
156
Alteplase
Fibrinolytics Acute MI PE Ischemic stroke
157
Streptokinase
Fibrinolytics Acute MI VTE
158
Tenecteplase
Fibrinolytics | Acute MI
159
Glyceryl trinitrate
Nitrate Angina. (sublingual spray/tablet may be repeated every 5 minutes intervals and medical attention sought after 3) Control of hypertension and ichemia after/during surgery CHF Anal fissure
160
Isosorbide dinitrate
Nitrate Angina Left ventricular failure
161
Isosorbide mononitrate
Nitrate | Angina
162
Dobutamine
Ionotropic sympathomimetics Support in infarction, surgery, shock and ventilation Cardiac stress testing
163
Adrenaline
``` Vasoconstricting sympathomimetic CPR Acute hypotension Acute anaphylaxis Bradycardia following MI Priapism associated with alprostadil ```
164
Bumetanide
Loop diuretics | Oedema
165
Furosemide
Loop diuretic Oedema Resistant hypertension
166
Torasemide
Loop diuretic Oedema Hypertension
167
Mannitol
Osmotic diuretic Cerebral oedema Raised intra ocular pressure
168
Amiloride
Potassium sparing diuretic Oedema Potassium conservation with loop and thiazides
169
Triamterene
Potassium sparing diuretic Oedema Potassium conservation with loop and thiazides
170
Chlortalidone
``` Thiazide related diuretic Ascites due to cirrhosis Oedema due to Nephrotic syndrome Hypertension Mild to moderate chronic heart failure Nephrogenic/partial pituitary diabetes insipidus ```
171
Metolazone
Thiazide related diuretic Oedema Hypertension
172
Cilostazol
Antiplatelet | Intermittent claudication without rest pain or peripheral tissue necrosis
173
Inositol
Nicotinic. Acid derivative (lipid modifyer) | Peripheral vascular disease
174
Moxisylyte
Peripheral vasodilator | Primary Raynauds
175
Naftidrofuryl
Peripheral vasodilator Peripheral vascular disease Cerebral vascular disease
176
Sodium tetradecyl sulfate
Sclerosant | Reticular/spider/varicose veins
177
Aclidinium bromide
Inhaled antimuscarinic | COPD maintenance
178
Glycopyrronium bromide
Inhaled antimuscarinic COPD maintenance Hyperhidrosis
179
Ipratropium bromide
``` Inhaled antimuscarinic 30-60 minutes onset, duration 3-6h Reversible airway obstruction Acute bronchospams Severe or life threatening acute asthma ``` Rhinorrhea
180
Tiotropium
Inhaled antimuscarinic Maintenance of COPD Severe asthma
181
Umeclidinium
Long acting antimuscarinic | Maintenance of COPD
182
Formoterol
Long acting beta agonists Chronic asthma COPD
183
Indacaterol
Long acting beta agonist | COPD maintenance
184
Olodaterol
Long acting beta agonist | COPD maintenance
185
Salmeterol
Long acting beta agonists COPD Chronic asthma
186
Salbutamol
Short acting beta agonists Asthma Acute bronchospams
187
Terbutaline
Short acting beta agonists Asthma Exacerbation of reversible Airways obstruction Uncomplicated premature labour
188
Fluticasone
Corticosteroid Prophylaxis of asthma Allargic rhinitis Nasal polyps Potent topical for severe inflammatory skin disorders and psoriasis
189
Mometasone
Corticosteroids Prophylaxis of asthma Allergic rhinitis Nasal polyps 0.1% cream is potent for severe inflammatory skin disorders and psoriasis
190
Benralizumab
Monoclonal antibodies | Severe eosinophilic asthma
191
Mepolizumab
Monoclonal antibodies | Add on for severe refractory eosinophilic asthma
192
Omalizumab
Monoclonal antibodies Prophylaxis of severe persistent allergic asthmq Chronic spontaneous urticaria not responding to antihistamines
193
Montelukast
Leukotreine receptor antagonists Prophylaxis of asthma Seasonal allergic rhinitis with asthma
194
Nedocromil
Mast cell stabiliser | Prophylaxis of asthma
195
Sodium cromoglicate
Mast cell stabiliser Prophylaxis of asthma Food allergy Allergic conjunctivitis Seasonal keratoconjunctivitis Prophylaxis of allergic rhinitis
196
Roflumilast
Phosphodiesterase type 4 inhibitor | Severe COPD with chronic bronchitis and exacerbations (adjunct)
197
Ephedrine
Vasoconstricting sympathomimetic Reversal of hypotension from spinal or epidural anaesthesia Neuropathic oedema Nasal congestion and Sinusitis
198
Aminophylline
Xanthine Severe acute asthma Severe acute exacerbation of COPD Chronic asthma
199
Theophylline
Xanthine | Severe acute and chronic asthma
200
Acrivastine
Non sedating antihistamine | Hayfever, chronic idiopathic urticaria
201
Cetirizine
Non sedating antihistamine | Hayfever, chronic idiopathic urticaria, atopic dermatitis
202
Fexofenadine
Non sedating antihistamine | Seasonal allergic rhinitis, chronic idiopathic urticaria
203
Loratadine
Non sedating antihistamine | Hayfever, chronic idiopathic urticaria
204
Alimemazine
Sedating antihistamine | Urticaria, Pruritis
205
Chlorphenamine
Sedating antihistamine Hayfever, urticaria, food allergy, drug reactions, chickenpox itch Emergency treatment for anaphylaxis
206
Clemastine
Sedating antihistamine | Hayfever, urticaria
207
Hydroxyzine
Sedating antihistamine | Pruritis
208
Ketotifen
Sedating antihistamine | Allergic rhinitis
209
Promethazine
Sedating antihistamine Hayfever, urticaria (and insomnia with it) Emergency treatment for anaphylaxis Sedation Nausea, vomiting, vertigo, motion sickness
210
C1 esterase inhibitor
Complementary regulatory proteins | Hereditary angioedema
211
Acetylcysteine
Mucolytic Reduction of sputum viscosity Tear deficiency /abnormal mucus (eye drops)
212
Carbocisteine
Mucolytic | Reduction of sputum viscocity
213
Dornase alfa
Mucolytics | Cistic fibrosis FVC over 40%
214
Ivacaftor
Mucolytic | Cystic fibrosis
215
Mannitol
Mucolytic | Cystic fibrosis as add on therapy
216
Pholcodine
Cough suppressant | Dry cough
217
Pirfenidone
Antifibrotic | Mild to moderate idiopathic pulmonary fibrosis
218
Doxapram
Respiratory stimulants Post operative respiratory depression Acute respiratory failure
219
Donepezil
Centrally acting anticholinesterase | Mild to moderate dementia in alzheimer's
220
Galantamine
Centrally acting anticholinesterase | Mild to moderately severe dementia in alzheimer's
221
Rivastigmine
Centrally acting anticholinesterase | Mild to moderate dementia in alzheimer's
222
Memantine
NMDA receptor antagonists | Moderate ot severe dementia in alzheimer's
223
Brivaracetam
Antiepileptic | Adjunct in partial onset seizures with or without secondary generalisation
224
Carbemazepine
Antiepileptic Focal and secndarey generalised tonic clinic seizures Primary generalised tonic clinic seizures Trigeminal neuralgia Prophylaxis of bipolar unresponsive to lithium Adjunct in acute alcohol withdrawal Diabetic neuropathy
225
Ethosuximide
Antiepileptic Absence seizures Myoclonic seizures
226
Fosphenytoin
Antiepileptic Status epilipticus Seizures associated with neurosurgery or head injury
227
Gabapentin
``` Antiepileptic Focal seizures with or without secondary generalisation Peripheral neuropathic pain Migraine prophylaxis Menopause symptoms in breast cancer ```
228
Lacosamide
Antiepileptic | Focal seizures with or without secondary generalisation
229
Lamotrigine
Antiepileptic Focal, tonic clinic seizures Seizures associated with lennox gastaut Bipolar disorder with or without valproate
230
Levetiracetam
Antiepileptic | Focal, Myoclonic, tonic clinic seizures
231
Perampanel
Antiepileptic | Adjunct to Focal seizures
232
Phenytoin
Antiepileptic Tonic clonic, Focal seizures Seizures from neurosurgery or head injury Status epilipticus
233
Pregabalin
Antiepileptic Peripheral and central neuropathic pain Adjunct for Focal seizures Generalised anxiety disorder
234
Rufinamide
Antiepileptic | Seizures in lennox gastaut
235
Sodium valproate
Antiepileptic All epilepsy Migraine prophylaxis Mania
236
Tiagabine
Antiepileptic | Focal seizures uncontrolled with others
237
Topiramate
Antiepileptic Generalised tonic clonic seizures Seizures associated with lennox gastaut Migraine prophylaxis
238
Vigabatrin
Antiepileptic | Adjunct in Focal seizures not controlled with others
239
Zonisamide
Antiepileptic | Focal seizures
240
Phenobarbital
Barbiturate antiepileptic All forms of epilepsy except absence Status epilipticus CD3
241
Primidone
Barbiturate antiepileptic All forms of epilepsy except absence Essential tremor
242
Clobazam
Benzodiazepine Adjunct in epilepsy Anxiety CD4-1
243
Clonazepam
``` Benzodiazepine All forms of epilepsy Myoclonus Panic disorder resistant to antidepressant CD4-1 ```
244
Thiopental
Barbiturate antiepileptic Status epilipticus Induction of anaesthesia Reduction of raised intracranial pressure
245
Lorazepam
``` Benzodiazepine Anxiety (and associated insomnia) Acute panic attacks Conscious sedation Premeditation Status epilipticus Febrile convulsions CD4-1 ```
246
Midazolam
``` Benzodiazepine Status epilipticus Febrile convulsions Conscious sedation Premeditation Confusion and restlessness in palliative care Convulsions in palliative care CD3 ```
247
Buspirone
Serotonin receptor agonist antidepressant | Anxiety
248
Alprazolam
Benzodiazepine Anxiety CD4-1
249
Chlordiazepoxide
Benzodiazepine Anxiety Alcohol withdrawal CD4-1
250
Diazepam
``` Benzodiazepine Muscle spasm Tetanus Anxiety (and associated insomnia} Panic attacks Alcohol withdrawal Drug induced dystonic reactions Conscious sedation Status epilipticus Febrile convulsions Dyspnoea associated eith anxiety in palliative care CD4-1 ```
251
Meprobamate
Non benzodiazepine hypnotic Anxiety CD3
252
Atomoxetine
Centrally acting sympathomimetics | ADHD
253
Methylphenidate
Centrally acting sympathomimetics ADHD Narcolepsy CD2
254
Dexamfetamine
Centrally acting sympathomimetics Narcolepsy Refractory ADHD CD2
255
Lis dexamfetamine
Centrally acting sympathomimetics ADHD CD2
256
Guanfacine
Alpha adrenoreceptor agonist (sympathomimetics) | ADHD when stimulants unsuitable
257
Asenapine
Second generation antipsychotic | Moderate to severe manic episodes (bipolar)
258
Lithium
``` Antipsychotic Mania Bipolar Recurrent depression Aggressive or self harming behaviour ```
259
Agomelatine
Melatonin receptor agonist (antidepressant) | Major depression
260
Isocarboxazid
Monoamine oxidase A and B inhibitor (antidepressant) | Depressive illness
261
Phenelzine
Monoamine oxidase A and B inhibitor (antidepressant) | Depressive illness
262
Moclobemide
Monoamine oxidase A inhibitor (antidepressant) Depressive illness Social anxiety disorder
263
Reboxetine
Noradrenaline reuptake inhibitor | Major depression
264
Citalopram
Serotonin reuptake inhibitor (antidepressant) Depressive illness Panic disorder
265
Fluoxetine
``` Serotonin reuptake inhibitor (antidepressant) Major depression Bulimia nervosa OCD Menopausal symptoms in breast cancer ```
266
Paroxetine
``` Serotonin reuptake inhibitor (antidepressant) Major depression Social anxiety disorder PTSD OCD Generalised anxiety disorder Panic disorder Menopausal symptoms in breast cancer ```
267
Sertraline
``` Serotonin reuptake inhibitor (antidepressant) Depressive illness OCD Panic disorder PTSD Social anxiety disorder ```
268
Duloxetine
``` Serotonin and noradrenaline reuptake inhibitor Major depressive disorder Generalised anxiety disorder Diabetic neuropathy Stress urinary incontinence ```
269
Venlafaxine
``` Serotonin and noradrenaline reuptake inhibitor Major depression Generalised anxiety disorder Social anxiety disorder Menopausal symptoms in breast cancer ```
270
Trazadone
Serotonin uptake inhibitor Depressive illness Anxiety
271
Mianserin
Tetracyclic antidepressant | Depressive illness
272
Mirtazepine
Tetracyclic antidepressant | Major depression
273
Amitriptyline
``` Tricyclic antidepressant Abdominal pain or discomfort Major depressive disorder Neuropathic pain Migraine prophylaxis Chronic tension headache prophylaxis ```
274
Clomipramine
Tricyclic antidepressant Depressive illness Phobic and obsessional States Adjunct in cataplexy with Narcolepsy
275
Dosulepin
Tricyclic antidepressant | Depressive illness
276
Doxepin
Tricyclic antidepressant Depressive illness Pruritis in eczema (cream)
277
Imipramine
Tricyclic antidepressant Depressive illness Nocturnal enuresis
278
Nortriptyline
Tricyclic antidepressant Depressive illness Neuropathic pain
279
Tryptophan
Antidepressant | Treatment resistant depression
280
Vortioxetine
Antidepressant | Major depression
281
Chlorpromazine
``` First generation antipsychotic Schizophrenia and other psychoses Mania Severe anxiety Intractable hiccup Nausea and vomiting in terminal illness ```
282
Flupentixol
First generation antipsychotic Schizophrenia and other psychoses Depression
283
Haloperidol
``` First generation antipsychotic Nausea and vomiting (incl palliative) Schizophrenia Psychoses Mania/hypomania Organic brain damage Agitation and restlessness in the elderly/palliative Tourettes, tics, intractable hiccup ```
284
Loxapine
First generation antipsychotic | Rapid control of mild to moderate agitation (Schizophrenia/bipolar)
285
Pericyazine
First generation antipsychotic Schizophrenia, psychoses Anxiety, psychomotor agitation and violent behaviour
286
Perphenazine
First generation antipsychotic Schizophrenia and other psychoses Mania Severe nusea and vomiting
287
Pimozide
First generation antipsychotic Schizophrenia Monosymotomatic hypochondriac psychosis Paranoid psychosis
288
Prochlorperazine
``` First generation antipsychotic Schizophrenia and other psychoses Mania Severe anxiety Acute nausea and vomiting (and prevention) Labyrinthine disorder ```
289
Sulpride
First generation antipsychotic | Schizophrenia (Higher maximum with predominantly positive symptoms)
290
Trifluoperazine
``` First generation antipsychotic Schizophrenia and other psychoses Psychomotor agitation and violence Severe anxiety Severe nausea and vomiting ```
291
Zuclopenthixol
First generation antipsychotic | Schizophrenia and other psychoses
292
Amisulpride
Second generation antipsychotic | Acute psychotic episode of schizophrenia and the disorder with predominantly negative symptoms
293
Aripiprazole
Second generation antipsychotic Maintenance of schizophrenia, mania Agitation and disturbed behaviour
294
Clozapine
Second generation antipsychotic Resistant Schizophrenia Psychoses in Parkinsons
295
Lurasidone
Second generation antipsychotic | Schizophrenia
296
Olanzapine
``` Second generation antipsychotic Schizophrenia Mania Bipolar Agitation and disturbed behaviour ```
297
Quetiapine
Second generation antipsychotic Schizophrenia Treatment of mania/depression in bipolar Major depression
298
Rispeidone
Second generation antipsychotic Schizophrenia and other psychoses Mania Aggression in alzheimer's
299
Promazine
First generation antipsychotic Psychomotor agitation Agitation and restlessness in elderly
300
Piracetam
CNS stimulant | Adjunct in cortical Myoclonus
301
Tetrabenazine
Monoamine depleting drug Movement disorders from Huntington and neurological conditions Moderate to severe tardive dyskinesia
302
Botulinum toxin
``` Muscle relaxant Focal spasticity Prophylaxis of headaches Ankle disability from stroke Crows feet ``` (B) just spasmodic totticollis (cervical dystonia)
303
Orphenadrine
Antimuscarinic Parkinsonism Drug induced extrapyrimidal symptoms (not tardive dyskinesia)
304
Procyclidine
Antimuscarinic Parkinsonism Extrapyrimidal symptoms (not tardive dyskinesia) Acute dystonia
305
Entacapone
COMT inhibitor | Adjunct to cobeneldopa or cocareldopa in Parkinsons with end of dose motor fluctuations
306
Tolcapone
COMT inhibitor | Adjunct to cobeneldopa or cocareldopa in Parkinsons with end of dose motor fluctuations if another COMT inappropriate
307
Co-beneldopa or co-careldopa
Dopamine precursor | Parkinsons disease
308
Amantadine
Dopamine receptor agonist Parkinsons disease Post herpetic neuralgia Influenza a prophylaxis and treatment
309
Apomorphine
Dopamine receptor agonist | Refractory motor fluctuations in parkinsons (off episodes) inadequately controlled by other dopaminergics
310
Bromocriptine
``` Dopamine receptor agonist Prevention of lactation Hypogonadism Galactorrhoea Infertility Acromegaly Prolactinoma Parkinsons ```
311
Cabergoline
Ergot derived Dopamine receptor agonist Prevention of lactation Hyperprolactinaemia Parkinsons (others inappropriate)
312
Pergolide
Ergot derived Dopamine receptor agonist | Parkinsons
313
Pramipexole
Dopamine receptor agonist Parkinsons Restless leg syndrome
314
Ropinorole
Dopamine receptor agonist Parkinsons Restless leg syndrome
315
Rotigotine
Dopamine receptor agonist Parkinsons Restless leg syndrome
316
Rasagiline
MAOB inhibitor | Parkinsons for end of dose fluctuations
317
Selegiline
MAOB inhibitor Parkinsons to reduce end of dose deterioration Symptomatic parkinsonism
318
Cyclizine
Antihistamine antiemetic Nausea, vomiting, vertigo, motion sickness, labyrinthine disorder Different doses when associated with vestibular disorder, palliative care
319
Nabilone
Cannabinoid antiemetic | Nausea and vomiting caused by cytotoxic chemotherapy, unresponsive to conventional
320
Domperidone
Dopamine receptor antagonist antiemetic Relief of nausea and vomiting Gastro intestinal pain in palliative care
321
Metoclopramide
Dopamine receptor antagonist antiemetic Nausea and vomiting including that associated with acute migraine. Delayed chemo induced nausea and vomiting Radiotherapy induced nausea and vomiting Prevention of post op nausea and vomiting Hiccup/nausea and vomiting in palliative care
322
Aprepitant
NK receptor antagonist antiemetic | Adjunct for nausea and vomiting associated with moderately and highly emetohenic chemotherapy
323
Fosaprepitant
NK receptor antagonist Adjunct to dexamethasone and serotonin antagonist to prevent nausea and vomiting associated with moderately and highly emetogenic chemotherapy
324
Granisetron
Serotonin receptor antagonists Nausea and vomiting induced by cytotoxic chemotherapy Prevention/treatment of postoperative nausea and vomiting
325
Ondansetron
Serotonin receptor antagonists Moderately and severely (Higher dose) emetogenic chemotherapy or Radiotherapy Prevention and treatment of postoperative nausea and vomiting
326
Cinnarizine
Sedating antihistamine Vertigo, tinnitus nausea and vomiting in minieres Motion sickness
327
Promethazine
Sedating antihistamine Nausea, vomiting, labyrinthine disorder Motion sickness prevention/treatment (works longer as teoclate)
328
Hyoscine hydrobromide
``` Antimuscarinic Motion sickness Hypersalivation with clozapine Excessive respiratory secretion Bowel colic in palliative care Premeditation ```
329
Levomepromazine
First generation antipsychotics Pain in palliative care (reserved for distressed with severe pain) Restlessness and confusion in palliative care Nausea and vomiting in palliative care Schizophrenia
330
Betahistine
Histamine analogue | Vertigo tinnitus hearing loss associated with menieres
331
Paracetamol
``` Non opioid analgesic Mild to moderate pain and pyrexia 0.5-1g every 4 to 6 hours. Max 4g. (15mg/kg up to 50kg) 2/4months (post immunisation) =60mg at vaccination, after 4-6hs (2 doses) Every 4-6h; 3-5m = 60mg 6m-1y = 120mg 2-3y = 180mg 4-5y = 240mg 6-7y = 240 - 250mg 8-9y = 360 - 375mg 10 - 11 = 480 - 500mg 12 - 15 = 480 - 750mg ``` Max 3g if ris of Hepatitoxicity
332
Nefopam
Non opioid centrally acting analgesic | Moderate pain
333
Buprenorohine
``` Opioid analgesic. Moderate to severe pain Premeditation Intra operative analgesia Adjunct in opioid dependance Chronic cancer pain CD3 ```
334
Codeine
``` Opioid analgesic Acute diarrhoea Mild to moderate pain Dry or painful cough CD5 ```
335
Diamorphine
``` Opioid analgesic Acute pain Chronic pain Acute pulmonary oedema Myocardial infarction CD2 ```
336
Dihydrocodeine
Opioid analgesic Moderate to severe pain Chronic severe pain CD5
337
Fentanyl
``` Opioid analgesic Chronic intractable pain Spontaneous respiration Assisted ventilation Breakthrough pain CD2 ```
338
Morphine
``` Opioid analgesic Pain Cough in terminal disease Premeditation Myocardial infarction Acute pulmonary oedema Dyspnoea in palliative care CD2 ```
339
Oxycodone
Opioid analgesic Post op and moderate to severe pain CD2
340
Pethidine
``` Opioid analgesic Acute pain Obstetric analgesia Premeditation Post operative pain CD2 ```
341
Tramadol
Opioid analgesic Moderate to severe pain Post operative pain CD3
342
Pizotifen
Sedating antihistamine | Prevention of vascular headache, migraine or cluster headache
343
Tolfenamic acid
NSAID | Treatment of acute migraine
344
Ergotamine
Ergot alkaloid | Management of cluster headache
345
Almotriptan
Serotonin receptor agonist | Treatment of acute migraine
346
Rizatriptan
Serotonin receptor agonist | Treatment of acute migraine
347
Sumatriptan
Serotonin receptor agonist | Treatment of acute migraine or cluster headache
348
Zolmitriptan
Serotonin receptor agonist | Treatment of acute migraine or cluster headache
349
Capsaicin
Plant alkaloid analgesic Post herpetic neuralgia Painful diabetic neuropathy Symptomatic relief of osteoarthritis
350
Flurazepam
Benzodiazepine Insomnia CD4-1
351
Nitrazepam
Benzodiazepine Insomnia CD4-1
352
Temazepam
``` Benzodiazepine Insomnia Concious sedation Premedication CD3 ```
353
Chloral hydrate
Hypnotic/sedative | Insomnia
354
Chlormethizole
Hypnotic/sedative Severe insomnia Restlessness and agitation Alcohol withdrawal
355
Melatonin
Sedative/hypnotic | Insomnia.
356
Zaleplon
Hypnotic/sedative | Insomnia
357
Zolpidem
Hypnotic /sedative Insomnia CD4-1
358
Zopiclone
Hypnotic /sedative Insomnia CD4-1
359
Sodium oxybate
CNS depressant Narcolepsy with cataplexy CD2
360
Pitolisant
CNS stimulant | Narcolepsy with or without cataplexy
361
Modafinil
CNS stimulant sympathomimetic | Excessive sleepiness associated with narcolepsy
362
Disulfiram
Aldehyde dehydrogenase inhibitor | Adjunct in alcohol dependance
363
Acamprosate
Gamma aminobutyric acid analogue | Maintenance of abstinence in alcohol dependant
364
Nalmefene
Opioid receptor antagonist | Reduction of alcohol consumption if high drinking risk
365
Naltrexone
Opioid receptor antagonist | Adjunct to prevent relapse in formerly opioid dependant
366
Buropion
SNRI antidepressant | Aid smoking cessation
367
Varenicline
Nicotine receptor agonist | Smoking cessation
368
Methadone
Opioid analgesic Severe pain Adjunct in opioid dependance Cough in terminal illness CD2
369
Lofexidine
Alpha2 agonist | Management of opioid withdrawal symptoms
370
Amikacin
Aminoglycoside | Serious gram negative infections resistant to gentamicin
371
Gentamicin
``` Aminoglycoside Gram positive bacterial endocarditis or HACEK endocarditis Septicemia, pyelonephritis, prostatitis CNS infection Surgical prophylaxis ``` Bacterial eye infections Bacterial infection in otitis externa
372
Neomycin
Aminoglycoside Bowel sterilisation Hepatic coma Bacterial infection in otitis externa Bacterial skin infection
373
Streptomycin
Aminoglycoside Tuberculosis Brucellosis (with doxycycline) Enterococcal endocarditis
374
Tobramycin
Aminoglycoside Septicemia, Cns Infection, pyelonephritis Urinary tract infection Psuedomonas aeruginosa (CF) Local infection treatment (eye)
375
Ertapenem
``` Carbapenem Abdominal infection Gynaecological infection Diabetic foot infection Colorectal surgery prophylaxis ```
376
Meropenem
``` Carbapenem Septicemia Lower respiratory infection (CF) Meningitis Endocarditis ```
377
Cefadroxil
First generation cephalosporin Skin infections Uncomplicated urinary tract infection
378
Cefalexin
First generation cephalosporin | Prophylaxis of recurrent uti
379
Cefaclor
Second generation cephalosporin Pneumonia Lower uti CF haemophillus influenzae
380
Cefuroxime
``` Second generation cephalosporin Lyme disease Lower uti or pyelonephritis Surgical prophylaxis Open fractures ``` Prophylaxis of endopthalmitis after cataract surgery (injection)
381
Cefixime
Third generation cephalosporin | Uncomplicated gonorrhoea
382
Cefotaxime
Third generation cephalosporin Uncomplicated gonorrhoea Haemophillus epiglottis Alternative to benzyl penicillin in suspected meningococcal disease
383
Ceftriaxone
``` Third generation cephalosporin Pneumonia Complicated uti COPD exacerbations Skin and soft tissue infection Meningitis, endocarditis Syphilis otitis media ```
384
Dalbavancin
Glycopeptide antibacterial | Skin infections
385
Teicoplanin
Glycopeptide antibacterial C diff Endocarditis Surgical prophylaxis
386
Vancomycin
``` Glycopeptide antibacterial C diff Pneumonia Meningitis Endocarditis Surgical prophylaxis if high risk MRSA ```
387
Clindamycin
``` Lincosamide Staph including MRSA bone/joint infections Skin and tissue infection Pneumocystis pneumonia Malaria ``` Acne vulgaris Bacterial vaginosis
388
Azithromycin
``` Macrolide Prevention of secondary strep a infection Respiratory tract infection Otitis media Skin and tissue infection Clamidya, gonorrhoea Lyme disease Typhoid CAP ``` Conjunctivitis (drops)
389
Clarithromycin
``` Macrolide Respiratory tract infection Skin and soft tissue infection Otitis media Lyme disease Petussis H pylori ```
390
Erythromycin
``` Macrolide Lyme disease Syphilis Chlamydia Diphttheria Rosacea Acne ```
391
Aztreonam
``` Monobactam Gram negative Gonorrhoea Cystitis Urinary tract infection Psuedomonas aeruginosa ```
392
Metronidazole
``` Nitro imidazole Anaerobic infection H pylori Chrons Leg ulcers Bacterial vaginosis Ulcerative gingivitis Tetanus ``` Exacerbation of Rosacea Fungating tumours
393
Tinidazole
``` Nitro imidazole Anaerobic infection Bacterial vaginosis Ulcerative gingivitis H pylori ```
394
Piperacillin
Antipseudomonal penicillin | Pneumonia, septicemia, complicated uti
395
Ticarcillin
Antipseudomonal penicillins | Psuedomonas and proteus infections
396
Benzyl penicillin
``` Beta lactamase sensitive penicillin Throat infections, otitis media, cellulitis, pneumonia Endocarditis Anthrax Meningitis ```
397
Phenoxymethylpenicillin
Beta lactamase sensitive penicillin Oral infection, tonsillitis, otitis media, cellulitis Rheumatic fever prevention Sinusitis
398
Amoxicillin
``` Broad spectrum penicillin Lyme disease Anthrax Dental abscess Uti Endocarditis ```
399
Ampicillin
Broad spectrum penicillin Bronchitis, pneumonia Endocarditis Listerial meningitis
400
Pivmecillinam
Penicillin Uncomplicated cystitis Bacteriuria Uti
401
Flucloxacillin
``` Penicillinase resistant penicillin Otitis externa, pneumonia, impetigo, cellulitis Endocarditis Osteomyelitis Lung infection prevention (CF) ```
402
Colistimethate
Polymyxin antibacterial | Psuedomonas aeruginosa in cf and other gram negative
403
Ciprofloxacin
``` Quinolone antibacterial Fistulating chrons Respiratory tract infection Uti Unccomplicated cystitis Prostatitis Gonorrhoea Anthrax ``` Superficial bacterial eye infection Corneal ulcers Acute otitis externa
404
Levofloxacin
``` Quinolone antibacterial Sinusitis Chronic bronchitis CAP UTI Prostatitis Anthrax ``` Local treatment of eye infections
405
Moxifloxacin
Quinolone antibacterial Sinusitis CAP Bronchitis Local treatment of eye infections
406
Ofloxacin
``` Quinolone antibacterial Uti Prostatitis Gonorrhoea Septicemia ```
407
Sulfadiazine
Sulfonamide antibacterial | Prevention of rheumatic fever
408
Demeclocycline
Tetracycline antibacterial Chlamydia, rickettsia Hyponatreamia
409
Doxycycline
``` Tetracycline antibacterial Chlamydia, rickettsia Sinusitis. Refractory uti Acne Rosacea Syphilis Lyme disease Anthrax Prophylaxis of malaria Peridontitis Aphthous ulceration ```
410
Lymecycline
Tetracycline antibacterial Chlamydia , rickettsia Acne
411
Oxytetracycline
Tetracycline antibacterial Chlamydia, rickettsia Rosacea. Acne
412
Tetracycline
``` Tetracycline antibacterial Chlamydia, rickettsia Rosacea, acne Diabetic diarrhoea in autonomic neuropathy Urethritis ```
413
Chloramphenicol
Antibacterial Haemophillus influenza Typhoid Superficial eye infections Bacterial infection in otitis externa
414
Daptomycin
Antibacterial (lipopeptide) Gram positive skin infections Endocarditis (staph)
415
Fidaxomicin
Antibacterial (macrolytic) | C diff
416
Fusidic acid
Antibacterial Staph infection Osteomyelitis Endocarditis Staph eye infection
417
Linezolid
Oxazolidinone antibacterial Pneumonia Skin infection
418
Trimethoprim
``` Antibacterial UTI Respiratory tract infection Pneumocystis jirovecci Acne Prostatitis ```
419
Rifabutin
Rifamycin antibacterial Mycobacterium avium Tuberculosis
420
Rifaximin
Rifamycin antibacterial Travellers diarrhoea Reduced recurrence of hepatic encephalopathy
421
Clofazimine
Antimycobacterial | Multibacilliary leprosy
422
Dapsone
Antimycobacterial Multibacilliary leprosy Dermatitis herpetiforms Prophylaxis and treatment of p jirovecci pneumonia
423
Rifampicin
``` Rifamycin antimycobacterial Brucellosis, legionnaires disease, staph Endocarditis Tuberculosis Leprosy ```
424
Amino salicylic acid
Antimycobacterial | Multiple drug resistant tuberculosis
425
Bedaquiline
Antimycobacterial | Multiple drug resistant tuberculosis
426
Capreomycin
Antimycobacterial | Drug resistant tuberculosis
427
Ethambutol
Antimycobacterial | Tuberculosis
428
Isoniazid
Antimycobacterial | Tuberculosis
429
Pyrazinamide
Antimycobacterial | Tuberculosis
430
Methenamine
Antibacterial | UTI
431
Nitrofurantoin
Antibacterial UTI Recurrent uti
432
Anidulafungin
Echinocandin antifungals | Invasive candidiasis
433
Caspofungin
Echinocandin antifungal | Invasive aspergillus, candidiasis
434
Micafungin
Echinocandin antifungal | Invasive and oesophageal candidiasis
435
Amphotericin
Polyene antifungal Invasive candidiasis Aspergillosis Leishmaniasis
436
Fluconazole
Triazole antifungal Candidal balanitis Vaginal candidiasis Tinea
437
Itraconazole
``` Triazole antifungal Candidiasis Tinea Aspergillosis Histoplasmosis ```
438
Posaconazole
Triazole antifungal Aspergillosis Candidiasis
439
Voriconazole
Triazole antifungal Aspergillosis Serious infection
440
Griseofulvin
Antifungal Dermatophyte infections Tinea capitis Tinea pedis (spray)
441
Atovaquone
``` Antiprotazoal Pneumocystis jirovecci (pneumonia) ```
442
Pentamidine
Pneumocystis jirovecci | Leishmaniasis
443
Albendazole
Anthelmintic Strongyloides infection Hookworm
444
Ivermectin
Anthelmintic Strongyloides Onchocerciasis
445
Mebendazole
Anthelmintic Threadworm Whipworm, hookworm, roundworm
446
Praziquantel
Anthelmintic | Tapeworm
447
Artemether with lumefantrine
Riamet - antimalarial | Falciparum malaria treatment
448
Atovaquone with proguanil
Malarone - antimalarial | Prophylaxis and treatment of falciparum malaria
449
Chloroquine
Antimalarial Rheumatoid arthritis Lupus erythematsus Prophylaxis and treatment of malaria (none falciparum) P vivax or p ovale infection in pregnancy when radical cure postponed
450
Mefloquine
Antimalarial | Prophylaxis and treatment of malaria
451
Primaquine
Antimalarial Adjunct p vivax or p ovale malaria Pneumocystis infection
452
Proguanil
Antimalarial. | Prophylaxis of malaria
453
Quinine
Antimalarial Nocturnal leg cramps Malaria treatment
454
Pyrimethamine
Antiprotazoal | Toxoplasmosis in pregnancy
455
Entecavir
Nucleoside analogue antiviral | Hepatitis b
456
Tenofovir
Nucleoside reverse transcriptase inhibitor antiviral | Hepatitis b
457
Adefovir
Nucleotide analogue antiviral | Hepatitis b
458
Peg interferon alfa
Interferon immunostimulant | Hepatitis c
459
Daclatasvir
5a inhibitor antiviral | Hepatitis c
460
Ribavirin
Nucleoside analogue antiviral Bronchiolitis Parainfluenza virus and adenovirus Hepatitis c
461
Sofosbuvir
Nucleotide analogue antiviral | Hepatitis c
462
Inosine pranobex
Antiviral Herpes simplex Genital warts Panencephalitis
463
Aciclovir
``` Nucleoside analogue antiviral Herpes simplex (and in eye/skin) Herpes/varicella zoster ```
464
Famciclovir
Nucleoside analogue antiviral Herpes zoster Genital herpes Herpes simplex
465
Valaciclovir
Nucleoside analogue antiviral Herpes zoster, simplex, labialis Genital herpes Cytomegalovirus
466
Ganciclovir
Nucleoside analogue antiviral Cytomegalovirus Herpetic keratitis (eye gel)
467
Foscarnet
Antiviral Cytomegalovirus Herpes simplex
468
Enfuvirtide
Hiv fusion inhibitor antiviral | HIV
469
Dolutegravir
HIV integrase inhibitor antiviral | HIV
470
Efavirenz
Non nucleoside reverse transcriptase inhibitor antiviral | HIV
471
Abacavir
Nucleoside reverse transcriptase inhibitor antiviral | HIV
472
Lamivudine
Nucleoside reverse transcriptase inhibitor antiviral | HIV
473
Tenofovir
Nucleoside reverse transcriptase inhibitor antiviral HIV Hepatitis B
474
Darunavir
Protease inhibitor antiviral | HIV
475
Saquinavir
Protease inhibitor antiviral | HIV
476
Cobicistat
Pharmacokinetic enhancer | Increases effects of antivirals
477
Oseltamivir
Neuraminidase inhibitor antiviral | Influenza prevention and treatment
478
Zanamivir
Neuraminidase inhibitor antiviral | Influenza prevention and treatment
479
Palivizumab
Monoclonal antibody | Lower respiratory tract disease by syncytial virus
480
Desmopressin
``` Pituitary hormone analogue Diabetes insipidus Nocturnal enuresis Polyuria /polydipsia Nocturia in MS Haemophilia and von willebrand disease Fibrinolytic response testing ```
481
Vasopressin
Pituitary hormone Diabetes insipidus Oesophageal variceal bleeding
482
Tolvaptan
Selective vasopressin antagonist (diuretics) Polycystic kidney disease with CKD Hyponatreamia from SIADH
483
Betamethasone
Corticosteroid Suppression of inflammatory/allergic disorder Congenital adrenal hyperplasia Inflammation in eye Eczematous inflammation in otitis externa Nose inflammation Oral ulceration Moderate if under 0.05% (betnovate), potent otherwise, for severe inflammatory skin disorders and psoriasis
484
Deflazacort
Corticosteroid | Suppression of inflammatory and allergic disorders
485
Dexamethasone
Corticosteroid Suppression of inflammatory and allergic disorder Croup Congeniral adrenal hyperplasia Adjunct in bacterial meningitis Nausea and vomiting in palliative care Headaches due to raised intracranial pressure Cerebral oedema Local inflammation of joints and soft tissue - injection Inflammation of eye and Macular oedema
486
Fludrocortisone
Corticosteroid Neuropathic postural hypotension Mineralocorticoid replacement Adrenocorticol insufficiency from septic shock
487
Hydrocortisone
``` Corticosteroid Thyrotoxic crisis Adrenocorticol insufficiency from septic shock Hypersensitivity reactions Corticosteroid replacement Addisons IBD (UC, proctitis, proctosigmoiditis) Asthma Local inflammation of joint and soft tissue - injection ``` Oral and perioral lesions Mild if 0.1 - 2.5% (for insect bites and nappy rash 1%) - combined in canesten hc, daktacort, fucidin h, timodine - for eczema and nappy rash Butyrate is potent for severe inflammatory skin disorders and psoriasis
488
Methylprednisolone
Corticosteroid Suppression of inflammatory and allergic disorder Cerebral oedema Graft rejection reactions Multiple sclerosis relapse Local inflammation of joint and soft tissue - injection
489
Prednisolone
``` Corticosteroid COPD exacerbations Croup Asthma Suppression of inflammatory and allergic disorder Idiopathic thrombocytopenic purpura IBD Myasthenia gravis Proctitis Local inflammation of joints (injection) Inflammation of eye (drops) ``` Eczematous inflammation in otitis externa
490
Ketoconazole
Enzyme inhibitor imidazole derivative Cushings syndrome ``` Imidazole antifungal Tinea pedis Fungal skin infection Seborrhoeic dermatitis Pityriasis versicolor ```
491
Metyrapone
Enzyme inhibitor Cushings syndrome Resistant oedema due to increase aldosterone secretion. (cirrhosis, CHF)
492
Acarbose
Alpha glucosidase inhibitor | Diabetes
493
Metformin
Biguanide Type 2 diabetes Polycystic ovary syndrome
494
Alogliptin
DPP4 Inhibitor | Type2 diabetes
495
Linagliptin
DPP4 Inhibitor | Type2 diabetes
496
Sitagliptin
DPP4 Inhibitor | Type2 diabetes
497
Abiglutide
GLP1 receptor agonist | Type2 diabetes
498
Dulaglutide
GLP1 receptor agonist | Type2 diabetes
499
Liraglutide
GLP1 receptor agonist Weight management Type2 diabetes
500
Nateglinide
Meglitinide | Type2 diabetes
501
Canagliflozin
SGLT2 inhibitor | Type2 diabetes
502
Dapagliflozin
SGLT2 inhibitor | Type2 diabetes
503
Glimenclamide
Sulfonylurea | Type2 diabetes
504
Gliclazide
Sulfonylurea | Type2 diabetes
505
Glimepride
Sulfonylurea | Type2 diabetes
506
Pioglitazone
Thiaolodinediones | Type2 diabetes
507
Soluble insulin
Rapid acting insulin (actrapid, humulin s) Diabetes Diabetic keto acidosis
508
Insulin aspart
Rapid acting insulin (novorapid) | Diabetes
509
Insulin glulisine
Rapid acting insulin (apidra) | Diabetes
510
Insulin lispro
Rapid acting insulin (humalog) | Diabetes
511
Isophane insulin
Intermediate acting insulin (insuman, humulin I/m3) | Diabetes
512
Insulin degludec
Long acting insulin (tresiba) | Diabetes
513
Insulin detemir
Long acting insulin (levemir) | Diabetes
514
Insulin glargine
Long acting insulin (lantus, abasaglar, toujeo) | Diabetes
515
Glucagon
Glycogenolytic hormone Insulin induced hypoglycaemia Beta blocker poisoning
516
Diazoxide
Glycogenolytic hormone | Chronic intractable hypoglycemia
517
Nandrolone
Anabolic steroid Osteoporosis in postmenopausal women CD4-2
518
Alendronic acid
Bisphosphonate Osteoporosis in men or postmenopausal Prevention of corticosteroid induced osteoporosis
519
Ibandronic acid
Bisphosphonate Reduction of bone damage with bone metastases in breast cancer Hypercalcaemia of malignancy Postmenopausal osteoporosis
520
Pamidronate
Bisphosphonate Hypercalcaemia of malignancy Osteolytic lesions and bone pain in bone metastases in breast cancer or multiple myeloma Pagets disease
521
Risedronate
Bisphosphonate Pagets disease Postmenopausal osteoporosis Prevention of corticosteroid induced osteoporosis
522
Zolendronic acid
Bisphosphonate Pagets disease Postmenopausal or corticosteroid induced osteoporosis Reduction of bone damage with advanced malignancy Hypercalcaemia of malignancy
523
Calcitonin
Bone resorption inhibitor Hypercalcaemia of malignancy Pagets disease Prevention of acute bone loss with immobility
524
Teriparatide
Parathyroid hormone analogue | Postmenopausal, mens and corticosteroid induced osteoporosis
525
Denosumab
Monoclonal antibody Osteoporosis (postmenopausal, men) Bone loss from hormone ablation in prostate cancer Prevention of skeletal events with bone metastases
526
Quinagolide
Dopamine receptor agonist | Hyperprolactinaemia
527
Cetorelix
Anti Gonadorophin releasing hormone | Female infertility Adjunct
528
Ganirelix
Anti Gonadorophin releasing hormone | Female infertility Adjunct
529
Buserelin
``` Gonadorophin releasing hormone Endometriosis Pituitary desensitisation (before in vitro fertilisation) Advanced prostate cancer ```
530
Goserelin
Gonadorophin releasing hormone Prostate cancer Endometriosis or thinning before intra uterine surgery Before surgery for uterine fibroid (anaemia) Pituitary desensitisation before ivf
531
Danazol
Anti Gonadorophin releasing hormone Endometriosis Severe pain in fibro cystic breast disease Hereditary angioedema
532
Tetracosactide
Corticotrophin Diagnosis of Adrenocorticol insufficiency Alternative to corticosteroid Unlicensed for infantile spasms
533
Gonadorelin
Gonadorophin releasing hormone | Assessment of pituitary function
534
Chorioginadotrophin alfa
Gonadorophin | Infertility
535
Follitrophin alfa
Gonadotrophin Infertility Hypogonadism
536
Follitrophin delta
Gonadotrophin | Superovulation for assisted conception
537
Pegvisomant
Growth hormone receptor antagonist | Acromegaly
538
Somatotrophin
Growth hormone | Deficiency
539
Raloxifene
Bone resorption inhibitor Postmenopausal osteoporosis Breast cancer
540
Conjugated oestrogen
Premarin (oestrogen) Menopausal symptoms Prophylaxis of postmenopausal osteoporosis Premique with progestogen if have uterus
541
Estradiol
Oestrogen Menopausal symptoms Osteoporosis prophylaxis Elleste solo, estraderm, estradot, evorel, fems even, oestrogel, sandrena, zumenon Femoston, femseven conti/sequi, tridestra, Elleste duet, kliofem with progestogen
542
Ethinylestradiol
Oestrogen Hypogonadism Menstrual disorder Osteoporosis prophylaxis
543
Tibolone
Oestrogen Deficiency Osteoporosis prophylaxis
544
Norethisterone
``` Progestogen Endometriosis Uterine bleeding, menorrhagia Dysmenorrhoea Beast cancer Postpone menstruation Contraception ```
545
Progesterone
Progestogen Infertility Premenstrual syndrome, post natal depression, Uterine bleeding
546
Clomifene
Ovulation stimulant | Female infertility
547
Testosterone
Androgens Hypogonadism (deficiency) CD4-2
548
Cyproterone
Anti androgen Hypersexuality, sexual deviation. Hot flushes/tumor flare with gonadorelin analogue therapy
549
Thyrotropin alfa
Thyroid stimulating hormones Detection of Thyroid remnants and cancer Increase iodine uptake for ablation
550
Carbimazole
Imidazole antithyroid | Hyperthyroidism
551
Propylthiouracil
Thiouracil antithyroid | Hyperthyroidism
552
Iodide with iodine
Vitamin/trace element | Thyrotoxicosis
553
Levothyroxine
Thyroid hormone Hypothyroidism Hyperthyroidism blocking replacement regime
554
Liothyronine
Thyroid hormone Hypothyroidism Hypothyroid coma
555
Darifenacin
Urinary antimuscarinic | Urinary frequency/urgency/incontinence
556
Fesiterodine
Urinary antimuscarinic | Urinary frequency /urgency /incontinence
557
Oxybutynin
Urinary antimuscarinic Urinary frequency /urgency /incontinence Nocturnal enuresis with overactive bladder
558
Solifenacin
Urinary antimuscarinic | Urinary frequency /urgency /incontinence
559
Trospium chloride
Urinary antimuscarinic | Urinary frequency /urgency /incontinence
560
Propiverine
Antimuscarinic | Urinary frequency /urgency /incontinence with overactive bladder
561
Tolterodine
Antimuscarinic | Urinary frequency /urgency /incontinence
562
Mirabegron
Beta 3 agonist | Urinary frequency /urgency /incontinence
563
Alfuzosin
Apha blocker Benign prostatic hyperplasia Acute urinary retention with BPH
564
Doxazosin
Alpha blocker Hypertension BPH
565
Prazosin
``` Alpha blocker Hypertension CHF Raynauds BPH ```
566
Tamsulosin
Alpha blocker | BPH
567
Bethanechol chloride
Choline ester | Urinary retention
568
Dutasteride
5alpha reductase inhibitor | BPH
569
Finasteride
5alpha reductase inhibitor BPH Androgenetic alopecia
570
Citric acid with potassium citrate
Alkalising drugss | Releif of dyscomfort in mild UTI to alkalyse urine.
571
Estradiol with nomegestrol/dienogest
Combined contraceptive | Zoely, Qlaira
572
Ethinylestradiol with desogestrel
Combined contraceptive | Gedafel, marvelon, mercilon
573
Ethinylestradiol with drospirenone
Combined contraceptive | Daylette, lucette, yasmin
574
Ethinylestradiol with etonogestrel
Combined contraceptive | Nuvaring
575
Ethinylestradiol with gestodene
Combined contraceptive | Femodene, femodette, milinette
576
Ethinylestradiol with Levonorgestrel
Combined contraceptive | Levest, microgynon, rigevidon
577
Ethinylestradiol with norelgestromin
Combined contraceptive | Evra
578
Ethinylestradiol with norethisterone
Combined contraceptive | Loestrin
579
Ethinylestradiol with norgestimate
Combined contraceptive | Cilest
580
Norethisteorne with mestranol
Combined contraceptive | Norinyl 1
581
Ulipristal acetate
Progesterone receptor modulator Uterine fibroid Emergency contraception
582
Desogestrel
Progestogen contraceptive | Cerazette, cerelle, desomono
583
Levonorgestrel
Progestogen contraceptive Emergency contraception Contraception Intrauterine device (jaydess, mirena) or tablet (norgeston 30mg or levonelle 1.5mg)
584
Etonogestrel
Progestogen contraceptive | Nexplanon implant
585
Medroxyprogesterone
Progestogen contraceptive Dysfunctional uterine bleeding, Endometriosis, breast cancer, contraception Provera tablets, sayana press, depo Provera injections
586
Nonoxinol
Spermicidal gel
587
Avanafil
Phosphodiesterase type 5 inhibitors | Erectile dysfunction
588
Sildenafil
Phosphodiesterase type 5 inhibitors Pulmonary arterial hypertension Erectile dysfunction Digital ulcers
589
Tadalafil
Phosphodiesterase type 5 inhibitors Pulmonary arterial hypertension Erectile dysfunction Benign prostatic hyperplasia
590
Alprostadil
Prostoglandin | Erectile dysfunction
591
Metaraminol
Sympathomimetic vasoconstrictor | Priapism
592
Dapoxetine
Selective serotonin reuptake inhibitor | Premature ejaculation
593
Dinoprostone
Prostoglandin | Cervical ripening and induction of labour
594
Oxytocin
``` Oxytocic Induction of labour Cesarean section Prevention of postpartum haemorrhage after delivery of placenta Incomplete miscarriage ```
595
Carbetocin
Oxytocic | Prevention of uterine atony after cesarean section
596
Carboprost
Prostoglandin | Postpartum haemorrhage
597
Atosiban
Oxytocin receptor antagonist | Premature labour at 24 to 33 weeks
598
Mifepristone
Progesterone receptor modulator Cervical ripening for termination up to 84 days Labour induction in foetal death Medical termination
599
Gemeprost
Prostoglandin Cervical ripening prior to first trimester abortion Second trimester abortion or death
600
Gemeprost
Prostoglandin Cervical ripening prior to first trimester abortion Second trimester abortion or death
601
Misoprostol
Prostoglandin Termination of pregnancy following mifepristone Induction of labour
602
Dequalinium
Antiseptic /disinfectant | Bacterial vaginosis
603
Lactic acid
Prveention and treatment of bacterial vaginosis
604
Clotrimazole
Imidazole antifungal Vaginal candidiasis Fungal infection in otitis externa Fungal skin infection
605
Miconazole
Imidazole antifungal Vaginal and vulval candidasis Oral candidiasis Intestinal candidiasis Fungal skin and nail infection
606
Estradiol
Oestrogen | Improve vaginal endothelium in Menopausal vaginitis (vagifem)
607
Antithymocyte immunoglobulin
Prophylaxis of organ rejection | Treatment of rejection
608
Azathioprine
``` Antimetabolite Chrons, ulcerative colitis Rehumatoid arthritis Lupus erythematsus Autoimmune conditions Suppression of rejection Severe refractory eczema Myasthenia gravies ```
609
Ciclospirin
``` Calcineurin inhibitor Ulcerative colitis Rehumatoid arthritis Atopic dermatitis, psoriasis Organ transplant Nephrotic syndrome ```
610
Sirolimus
Non calcineurin inhibitor | Prophylaxis of organ rejection
611
Tacrolimus
Calcineurin inhibitor Prophylaxis of rejection Severe atopic eczema and prevention of flares (ointment)
612
Canakinumab
Monoclonal antibodies Acute gout Inflammatory syndromes
613
Basiiliximab
Monoclonal antibodies | Prophylaxis of rejection
614
Mycophenolate
Purine synthesis inhibitor | Prophylaxis of rejection
615
Belatacept
T cell activation inhibitors | Prophylaxis of rejection
616
Fampridine
Cholinergic receptor stimulator | Improvement of walking in multiple sclerosis
617
Interferon beta
Immunostimulant Relapsing, remitting multiple sclerosis with at least 2 attacks in previous 2 or 3 years. Demyelinating event with active inflammatory process
618
Glatiramer
Immunostimulant | Relapsing remitting multiple sclerosis
619
Dimethyl fumarate
Immunosupprrssants Plaque psoriasis Relapsing remitting multiple sclerosis
620
Fingolimod
``` Immunomodulating drug (suppressant) Highly active or rapidly evolving relapsing remitting multiple sclerosis ```
621
Alemtuzumab
Anti lymphocyte monoclonal antibodies | Relapsing remitting multiple sclerosis (active)
622
Natalizumab
Anti lymphocyte monoclonal antibodies | Highly active relapsing remitting multiple sclerosis or rapidly evolving
623
Ocrelizumab
Anti lymphocyte monoclonal antibodies | Multiple sclerosis
624
Teriflunomide
Pyrimidine synthesis inhibitor | Relapsing remitting multiple sclerosis
625
Atezolizumab
Monoclonal antibodies Urothelial carcinoma Non small cell lung cancer
626
Bevacizumab
Monoclonal antibodies | Metastatic Colorectal cancer or breast cancer
627
Cetuximab
Monoclonal antibodies Wild type metastatic Colorectal cancer Head and neck cancer
628
Nivolumab
Monoclonal antibodies Metastatic advanced myeloma Non small cell lung cancer
629
Rituximab
Monoclonal antibodies Rheumatoid arthritis Follicular myeloma
630
Trastuzumab
Monoclonal antibodies | Breast cancer HER2
631
Telotristat
Enzyme inhibitor | Carcinoid syndrome diarrhoea
632
Bendamustine
Alkylating antineoplastic drug | Chronic lymphocytic leukemia, myeloma, lymphoma
633
Busulfan
Alkylating antineoplastic drug | Chronic myeloid leukemia
634
Chlorambucil
Alkylating antineoplastic drug | Leukemias
635
Cyclophosphamide
Alkylating antineoplastic drug Rheumatoid arthritis Malignancy
636
Ifosfamide
Alkylating antineoplastic drug | Malignant disease
637
Melphalan
Antineoplastic alkylating drug | Multiple myeloma
638
Temozolomide
Alkylating antineoplastic drug | Malignant myeloma
639
Treosulfan
Alkylating antineoplastic drug | Ovarian cancer
640
Daunorubicin
Anthracycline antineoplastic | Myelogenous leukemia
641
Doxorubicin
Anthracycline antineoplastic | Acute leukemia, lymphoma, bladder tumours, carcinoma
642
Epirubicin
Anthracycline antineoplastic | Breast cancer, bladder cancer
643
Mitoxantrone
Anthracycline antineoplastic | Breast cancer, lymphoma, carcinoma
644
Azacitidine
Antimetabolite antineoplastic | Myekodysplastic syndromes
645
Capecitabine
Antimetabolite antineoplastic | Colon cancer
646
Cytarabine
Antimetabolite antineoplastic | Leukemia, lymphomatous meningitis
647
Fluorouracil
Antimetabolite antineoplastic Solid tumours, Colorectal cancer Skin lesions (efudix)
648
Mercaptopurine
Antimetabolite antineoplastic | Chrons, leukemia
649
Methotrexate
``` Antimetabolite antineoplastic Chrons Rheumatoid arthritis Psoriasis Neoplastic disease ```
650
Nelarabine
Antimetabolite antineoplastic | Lymphoblastic lymphoma
651
Pemetrexed
Antimetabolite antineoplastic | Non small cell lung cancer
652
Bleomycin
Cytotoxic antibiotic | Carcinoma, lymphoma
653
Mitomycin
Cytotoxic antibiotic Bladder tumors Breast and upper GI cancer
654
Pentostatin
Cytotoxic antibiotic | Leukemia
655
Trabectedin
Plank alkaloid. Sarcoma, ovarian cancer
656
Carboplatin
Platinum compounds | Ovarian and lung cancer
657
Cisplatin
Platinum antineoplastic | Testicular, lung, cervical, bladder, head and neck and ovarian cancer
658
Oxaliplatin
Platinum antineoplastic | Colorectal cancer
659
Etopside
Podophyllotoxin antineoplastic | Small cell carcinoma of bronchus
660
Carbazitaxel
Taxane antineoplastic | Prostate cancer
661
Docetaxel
Taxane antineoplastic | Breast cancer
662
Paclitaxel
Taxane antineoplastic | Ovarian cancer
663
Topotecan
Topoisonerase inhibitor antineoplastic | Colorectal cancer
664
Vinblastine
Vinca alkaloid antineoplastic | Cancers
665
Vincristine
Vinca alkaloid antineoplastic | Cancers
666
Asparaginase
Antineoplastic | Leukemia
667
Hydroxycarbamide
Antineoplastic Thrombocytopenia Chronic myeloid leukemia
668
Raltitrexed
Antineoplastic | Colorectal cancer
669
Folinic acid
Vitamin | Prevention of methotrexate induced effects
670
Rasburicase
Urate oxidases | Hyperuricaemia
671
Abiraterone
Anti androgen | Metastatic castration resistant prostate cancer
672
Bicalutamide
Anti androgen. | Prostate cancer
673
Dagarelix
anti gonadotrophin releasing hormone | Hormone dependant prostate cancer
674
Lanreotide
Somatostatin analogue Acromegaly Neuroendocrine tumors Thyroid tumours
675
Ocreotide
Somatostatin analogue Carcinoid tumour Acromegaly
676
Megestrol
Progestogen | Breast cancer
677
Fulvestrant
Anti oestrogen | Oestrogen receptor positive breast cancer
678
Tamoxifen
Anti oestrogen Oestrogen receptor positive breast cancer Anivulatory infertility Gynaecomastia
679
Anastrazole
Aromatase inhibitor | Adjunct in oestrogen receptor positive breast cancer
680
Exemestane
Aromatase inhibitor | Oestrogen receptor positive breast cancer
681
Letrozole
Aromatase inhibitor | Post Menopausal women with breast cancer
682
Interferon alfa
Immunostimulant | Leukemia
683
Aldesleukin
Interleukin | Renal cell carcinoma
684
Lenalidomide
Immunosupprrssants | Multiple myeloma
685
Bortezomib
Proteasome inhibitor | Multiple myeloma
686
Afatinib
Protein kinase inhibitor | EGFR mutations in lung cancer
687
Bosutinib
Protein kinase inhibitor | Chronic myeloid leukemia
688
Crizotinib
Protein kinase inhibitor | ALK positive advanced lung cancer
689
Erlotinib
Protein kinase inhibitor | Non small cell lung cancer
690
Everolimus
Protein kinase inhibitor Renal cell carcinoma. Liver/renal/heart transplant
691
Oxymetholone
Androstan derivative | Aplastic anaemia
692
Darbpoetin alfa
Epoetins | Anaemia associated with chronic renal failure or non myeloid malignancies
693
Epoetins alfa
Epoetin | Anaemia with chronic renal failure or cancer chemotherapy
694
Ferric carboxymaltose
Parenteral iron | Iron deficiency anaemia
695
Iron sucrose
Parenteral iron | Iron deficiency anaemia
696
Ferrous fumarate
Oral Iron | Iron deficiency anaemia (prophylaxis and therapeutic)
697
Ferrous gluconate
Oral iron | Iron deficiency anaemia (prophylaxis and therapeutic)
698
Ferrous sulfate
Oral iron | Iron deficiency anaemia (prophylaxis and therapeutic)
699
Folic acid
``` Vitamin Megaloblastic anaemia Prevention of neural tube defects Prevention of methotrexate side effects Prophylaxis of deficiency or hemolytic states in dialysis or when recieveing PN ```
700
cyanocobalamin
Vitamin B | Vitamin b12 deficiency of dietary origin
701
Hydroxocobalamin
Vitamin Prophylaxis of macrocytuc anaemia Poisoning with cyanides
702
Deferasirox
Iron chelator | Transfusion related iron overload
703
Desfeffioxamine
Iron chelator Iron poisoning Aluminium/iron overload
704
Filgrastim
Immunostimulant | Reduction in duration of neutropenia
705
Anagrelide
Cyclic amp phosphodiesterase inhibitor - antithrombotic | Thrombocytopenia
706
Eltrombopag
Antihaemorrhagic (thrombopoetin agonist) Idiopathic thrombocytopenic purpura Aplastic anaemia
707
Sodium bicarbonate
Electrolyte Alkalinisation of urine (relief from uti) Acidotic states Metabolic acidosis
708
Potassium chloride combinations
Electrolytes | Imbalance, prophylaxis, replacement
709
Sodium chloride
Electrolytes Deficiency prophylaxis Renal salt wasting Diabetic keto acidosis
710
Glucose
``` Nutrient Gestational diabetes/glucose tolerance test Hypoglycaemia Water replacement Cyanosis Diabetic keto acidosis ```
711
Cinacalcet
Bone resorption inhibitor Hyperparathyroidism Hypercalcaemia in carcinoma
712
Etelcalcetide
Bone resorption inhibitor | Hyperparathyroidism
713
Calcium carbonate
Electrolytes Phosphate binding Calcium deficiency
714
Calcium chloride/gluconate
Electrolytes Hypocalcaemia Gluconate - hyperkalaemia
715
Magnesium sulfate
``` Electrolytes Asthma Prevention of seizures in pre eclampsia/eclampsia Hypomagnesemia Arrythmias Rapid bowel evacuation ```
716
Albuminium hydroxide
Electrolytes Hyperphosphataemia in renal failure Antacid
717
Calcium acetate
Electrolytes | Hyperphosphataemia
718
Sevelamer
Phosphate binder | Hyperphosphataemia
719
Patiromer calcium
Cation exchange resin | Hyperkalaemia
720
Potassium chloride
Electrolytes Hypokaleamia Imbalance
721
Haem arginate
Blood product | Acute porphyria
722
Agalsidase alfa
Enzyme | Fabrys disease
723
Eliglustat
Enzyme inhibitor | Gaucher's disease
724
Imiglucerase
Enzyme | Gaucher's disease
725
Zinc acetate
Chelator | Wilsons disease
726
Zinc sulfate
Electrolytes | Deficiency
727
Sapropterin
Tetrahydrobiopterin derivative | Phenylketonuria
728
Retinol
Vitamin A | Deficiency
729
Pyridoxine
``` Vitamin b6 Deficiency Isoniazid neuropathy Sideroblastic anaemia Premenstrual syndrome ```
730
Thiamine
Vitamin b1 | Deficiency
731
Ascorbic acid
Vitamin c | Scurvy
732
Alfacalcidol
``` Vitamin D Renal impairment Rickets Hypocalcaemia Liver disease ```
733
Calcitriol
Vitamin D Renal osteodystrophy Postmenopausal osteoporosis
734
Cholecalciferol
Vitamin D 3 | Deficiency
735
Ergocalciferol
Vitamin D2 Deficiency from liver disease malabsorption Deficiency Hypocalcaemia
736
Tocopherol
Vitamin E | Deficiency from malabsorption (cholestalsis, CF)
737
Phytomenadione
Vitamin K Bleeding on warfarin Reversal of anticoagulant before surgery
738
Glucosamine
Chondroprotective | Osteoarthritis of the knee
739
Hydroxychloroquine
DMARD Active rheumatoid arthritis Systemic and discoid lupus erythematsus Dermatological conditions from sunlight
740
Leflunomide
DMARD | Active rheumatoid and psoriatic arthritis
741
Penicillamine
``` DMARD Active rheumatoid arthritis Wilsons disease Autoimmune hepatitis Cystinuria ```
742
Sodium aurothiomalate
DMARD | Active progressive rheumatoid arthritis
743
Sarilumab
Interleukin inhibitors | Active rheumatoid arthritis
744
Secukinumab
Interleukin inhibitor Psoriatic arthritis Ankylosing spondylitis
745
Ustekinumab
Interleukin inhibitors Plaque psoriasis Psoriatic arthritis Chrons disease
746
Baricitinib
Protein kinase inhibitor | Rheumatoid arthritis
747
Abatacept
T cell activation inhibitor | Rehumatoid and psoriatic arthritis
748
Adalimumab
``` TNF alpha inhibitor Plaque psoriasis Rheumatoid arthritis Psoriatic arthritis IBD ```
749
Etanercept
TNF alpha inhibitor Rheumatoid arthritis Plaque psoriasis
750
Golimumab
``` TNF alpha inhibitor Ulcerative colitis Rheumatoid arthritis Psoriatic arthritis Ankylosing spondylitis ```
751
Infliximab
``` TNF alpha inhibitor IBD Rehumatoid arthritis Ankylosing spondylitis Psoriatic arthritis Plaque psoriasis ```
752
Apremilast
Phosphodiesterase type 4 inhibitor Psoriatic arthritis Plaque psoriasis
753
Colchicine
Plant alkaloid Acute gout Short term prophylaxis during initial therapy with allopurinol/uricosuric drugs Prophylaxis of familial Mediterranean fever
754
Sulfinpurazone
Uricosuric Gout prophylaxis Hyperuricaemia
755
Allopurinol
Xanthine oxidase inhibitor Prophylaxis of gout and uric acid/calcium oxalate renal stones Prophylaxis of Hyperuricaemia associated with cancer chemotherapy
756
Febuxostat
Xanthine oxidase inhibitor Treatment of chronic Hyperuricaemia in gout Prophylaxis and treatment of Hyperuricaemia with chemo for haematologic malignancies
757
Neostigmine
Anticholinesterase Myasthenia gravis Reversal of non depolarising neuromuscular blockade
758
Pyridostigmine
Anticholinesterases | Myasthenia gravis
759
Cannabis extract
Cannabinoid | Adjunct for spasticity in multiple sclerosis
760
Baclofen
Centrally acting muscle relaxant Pain of muscle spasm in palliative care Hiccup Spasticity
761
Methocarbamol
Centrally acting muscle relaxant | Muscle spasm
762
Aceclofenac
NSAID | Pain and inflammation in rheumatoid arthritis, osteoarthritis and Ankylosing spondylitis
763
Celecoxib
NSAIDs | Pain and inflammation in rheumatoid arthritis, osteoarthritis and Ankylosing spondylitis
764
Dexibuprofen
NSAIDs Osteoarthritis Dysmenorrhoea Mild to moderate pain
765
Diclofenac
``` NSAIDs Pain and inflammation in rheumatic disease Acute gout Post op pain Migraine Fever in ear nose or throat infection ``` Inhibition of mitosis during cataract surgery and post op inflammation Seasonal allergic conjunctivitis (eye drops) Actinic keratosis (solaraze)
766
Etoricoxib
NSAIDs Pain and inflammation in osteoarthritis, rheumatoid arthritis and Ankylosing spondylitis Acute gout
767
Flurbiprofen
NSAIDs Pain, inflammation, migraine, post op, dysmenorrhoea Inhibition of Intra operative mitosis and post op inflammation (eye drops) Relief of sore throat (strefen)
768
Ibuprofen
NSAIDs | Pain, inflammation, migraine, post op, dental, pyrexia
769
Indometacin
NSAIDs Pain and inflammation in rheumatic disease Acute gout Dysmenorrhoea
770
Mefenamic acid
NSAIDs Pain and inflammation in rheumatoid arthritis, osteoarthritis, post op pain Dysmenorrhoea Menorrhagia
771
Meloxicam
NSAIDs Exacerbation of osteoarthritis Pain and inflammation in rheumatic disease and juvenile idiopathic arthritis
772
Naproxen
Nsaid Pain and inflammation in rheumatic disease Dysmenorrhoea Acute gout
773
Piroxicam
Nsaid Rheumatoid arthritis Ankylosing spondylitis Pain relief
774
Sulindac
Nsaid Pain and inflammation in rheumatic disease Acute gout
775
Hyaluronidase
``` Enzyme Enhance permeation of injections/anaesthetics Hypodermolysis Extravasation Haematoma ```
776
Azelastine
Antihistamines (eye) Seasonal allergic conjunctivitis Perennial conjunctivitis
777
Ketotifen
Antihistamines | Seasonal allergic conjunctivitis (eye)
778
Lodoxamide
``` Mast cell stabiliser Allergic conjunctivitis (eye) ```
779
Nepafenac
Nsaid (eye) | Post op pain and inflammation or risk of Macular oedema with cataract
780
Atropine
Antimuscarinic (eye drops) Cycloplegia Anterior uveitis
781
Cyclopentolate
Antimuscarinic eye drops Cycloplegia Uveitis
782
Carbomer
Ocular lubricant | Dry eye
783
Carmellose
Ocular lubricant | Dry eye
784
Hypromellose
Ocular lubricant | Tear deficiency
785
Propamidine
Antiprotazoal eye drops | Local treatment of eye infections
786
Tropicamide
Antimuscarinic | Funduscopy
787
Acetylcholine
Miotic. Parasympathomimetic | Cataract surgery
788
Oxybuprocaine
Local anaesthetic for eye
789
Acetazolamide
Carbonic anhydrase inhibitor Reduction of intra ocular pressure Glaucoma Epilepsy
790
Brinzolamide
Carbonic anhydrase inhibitor | Reduction of intra ocular pressure in hypertension or open angle glaucoma
791
Dorzolamide
Carbonic anhydrase inhibitor | Raised intra ocular pressure unresponsive or Adjunct to beta blocker
792
Pilocarpine
Miotic parasympathomimetic Primary angle closure glaucoma Dry mouth and dry eyes Xerostomia following irradiation for head and neck cancer
793
Bimatoprost
Prostoglandin analogues | Raised intra ocular pressure
794
Latanoprost
Prostoglandin analogues | Raised intra ocular pressure in open angle glaucoma
795
Travoprost
Prostoglandin analogues | Raised intra ocular pressure in open angle glaucoma
796
Apraclonidine
Alpha 2 agonist | Control or prevention of post op elevation of intra ocular pressure after surgery
797
Brimonidine
Alpha 2 agonist Raised intra ocular pressure in open angle glaucoma Facial erythema in Rosacea (gel)
798
Aflibercept
Vascular endothelial growth factor inhibitor | Macular degeneration/oedema
799
Fluocinolone
Corticosteroid Macular oedema Mild (0.0025%) to potent (0.025%) topical for severe inflammatory skin disorders and psoriasis (synalar)
800
Pseundoephedrine
Vasoconstricting sympathomimetic | Congestion of mucous membranes
801
Xylometazoline
Vasoconstricting sympathomimetic | Nasal congestion
802
Mupirocin
Antibacterial Eradication of staph from nasal carriage including MRSA Bacterial skin infections
803
Azelastine
Antihistamines | Allergic rhinitis
804
Chlorhexidine
``` Antiseptic Oral hygiene and plaque inhibition Oral candidiasis Gingivitis Denture stomatitis ```
805
Sodium fluoride
Vitamin | Prophylaxis of dental caries
806
Benzydamine
Nsaid | Painful inflammatory conditions of oropharynx
807
Nystatin
Antifungal | Oral candidiasis
808
Clobetasone
Moderate corticosteroid cream (eumovate) | Eczema and dermatitis
809
Clobetasol
Very potent corticosteroid (dermovate) Severe resistant inflammatory skin disorders and psoriasis Moderate scalp psoriasis
810
Polymyxins
Antibacterial | Bacterial skin infection
811
Silver sulfadiazine
Antibacterial sulfonamides Infection in burn wounds Finger tip injuries Infection of pressure sores /leg ulcers
812
Amorolfine
Antifungal | Nail infection
813
Terbinafine
Antifungal Tinea pedis/corporis/cruris Cutaneous candidiasis Pityriasis versicolor
814
Dimeticone
Parasiticides | Head lice
815
Malathion
Parasiticides Head lice Crab lice Scabies
816
Permethrin
Parasiticides Scabies Crab lice Head lice
817
Ichthammol
Anti infective | Chronic lichenified eczema
818
Dithranol
Antracen derivative | Psoriasis
819
Coal tar
``` Psoriasis Chronic atopic eczema Dandruff Seborrhoeic dermatitis Scaling itching ```
820
Acitretin
Retinoid | Severe extensive psoriasis
821
Tazarotene
Retinoid | Mild to moderate plaque psoriasis
822
Calcipotriol
Vitamin D analogue Plaque psoriasis Scalp psoriasis
823
Calcitriol
Vitamin D analogue | Plaque psoriasis
824
Crotamiton
Antipruritic
825
Co - cyprindiol
Anti androgen Moderate to severe acne Hirsutism
826
Benzoyl peroxide
``` Peroxide Acne vulgaris (acnecide, duac) ```
827
Azeliac acid
``` Antucomedonals .acne vulgaris Papulopustular Rosacea (skinoren and finacea) ```
828
Adapalene
Retinoid | Mild to moderate acne vulgaris (differin, epiduo)
829
Isotretinoin
Retinoid Mild to moderate acne (topical) Severe acne (oral)
830
Isotretinoin
Retinoid Mild to moderate acne (topical) Severe acne (oral)
831
Nicotinamide
Inflammatory acne vulgaris (freederm) | Vitamin B
832
Ivermectin
``` Anthelmintic Papulopustular Rosacea (soolantra) ```
833
Selenium
Vitamin Seborrhoeic dermatitis Dandruff Pityriasis versicolor (selsun)
834
Minoxidil
Vasodilator | Alopecia (regaine)
835
Heparinoid
Superficial thromboplebitis, bruising and haemotoma (gel/cream)

bnf (15 decks)

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