Classes/MOA Flashcards by Paige LaPointe

Q

MOA of acetaminophen (tylenol)

A

blocks peripheral pain impulse generation; inhibits hypothalamus heat regulation

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Q

MOA ibuprofen

A

inhibits COX1/COX2

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Q

SYNTHETIC DMARDS

A

Cellcept (semi-synthetic)

Sulfasalazine

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Q

Leukocyte migration inhibitor

A

colchicine

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Q

MOA of Rituxan

A

inhibits b-lymphocytes

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Q

non-purine xanthine oxidase inhibitor

A

Febuxostat (Uloric)

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Q

CORTICOSTEROID

A

Prednisone

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Q

MOA of abatacept (orencia)

A

inhibits t cells by binding to APC receptors

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Q

MOA of amitriptyline

A

inhibits 5HT, NE reuptake

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Q

IL-1 Receptor antagonist

A

Anakinra (Kinercet)

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Q

monoclonal antibody

A

Rituximab (Rituxan)

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Q

MOA of allopurinol

A

blocks uric acid production

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Q

MOA of hydroxychloroquine

A

T cell response suppression

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Q

NB-DMARDS

A

methotrexate

hydroxychloroquine

Tofacitinib (Xeljanz)

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Q

MOA of celecoxib (celebrex)

A

inhibits COX2

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Q

NB-DMARD that is a JAK inhibitor

A

Xeljanz

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Q

Sulfasalazine MOA

A

dec levels of IgA, IgM, RF

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Q

uricosuric

A

probenicid

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Q

Prednisone MOA

A

inhibits cytokines

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Q

MUSCLE RELAXANTS

A

Baclofen

Cyclobenzaprine

Dantrolene

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Q

MOA of probenicid

A

blocks PCT reabsorption of uric acid

Q

baclofen MOA

A

inhibits synaptic reflexes at SC level

Q

B-DMARDS

A

Etanercept (Enbrel)

Abatacept (Orencia)

Rituximab (Rituxan)

Anakinra (Kinercet)

Q

COX2 selective nsaid

A

celecoxib (celebrex)

xanthine oxidase inhibitor

allopurinol

NSAIDS

ibuprofen celebrex

Cellcept MOA

immunosuppresses both B and T cells

T cell activation inhibitor

abatacept (orencia)

MOA of tramadol (ultram)

mu receptor antagonist; inhibits reuptake of NE/5HT

TNF-alpha blocker

Etanercept (Enbrel)

Cyclobenzaprine MOA

reduces somatic motor activity

ANTI-GOUT

Colchicine Probenicid Allopurinol Uloric

ANALGESICS

acetaminophen tramadol

peripherally-acting muscle relaxant

dantrolene

MOA of etanercept

binds to TNF-alpha

traditional nsaid

ibuprofen

MOA of Uloric

reduces uric acid production

cholinergic agonist

pilocarpine

centrally-acting muscle relaxants

baclofen cyclobenzaprine

MOA of cyclophosphamide

prevents cell division

MOA of methotrexate

inhibits DNA production/production of cytokines

analgesic/antipyretic

acetaminophen (tylenol)

MOA of Xeljanz

inhibits JAK enzymes and prevents activity of immune cells

MOA of anakinra

antagonist of IL-1 receptor

anti-neoplastic, alkylating agent

cyclophosphamide

synthetic opioid analgesic

tramadol (ultram)

dantrolene MOA

inhibits release of Ca from skel muscle

MOA of colchicine

inhibits leukocyte migration/phagocytes

tricyclic antidepressant

amitriptyline

pilocarpine MOA

acts on muscarinic receptors to stimulate salivary gland secretion