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Flashcards in Classic Labs/Findings 2 Deck (20)
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1

Bronchogenic apical lung tumor on imaging?

Pancoast tumor (can compress SNS ganglion and cause Horner's syndrome)

2

"Brown" tumor of bone?

Hyperparathyroidism or osteitis fibrosa cystica (deposited hemosiderin from hemorrhage gives brown color)

3

Cardiomegaly with apical atrophy?

Chagas dz (Trypanosoma cruzi)

4

Cellular crescents in Bowman's capsule?

Rapidly progressive crescentic glomerulonephritis

5

"Chocolate cyst" of ovary?

Endometriosis (frequently involves both ovaries)

6

Circular grouping of dark tumor cells surrounding pale neurofibrils?

Homer-Wright rosettes (neuroblastoma, medulloblastoma, retinoblastoma)

7

Colonies of mucoid Pseudomonas in lungs?

Cystic fibrosis (autosomal-recessive mutation in CFTR resulting in fat-soluble vitamin deficiency and mucous plugs)

8

Decreased a-fetoprotein in amniotic fluid/maternal serum?

Down syndrome or other chromosomal abnormality

9

Degeneration of dorsal column nerves?

Tabes dorsalis (tertiary syphilis), subacute combined degeneration (dorsal columns + LCST affected)

10

Depigmentation of neurons in substantia nigra?

Parkinson's (basal ganglia disorder: rigidity, resting tremor, bradykinesia)

11

Desquamated epithelium casts in sputum?

Curschmann's spirals (bronchial asthma; can result in whorled mucous plugs)

12

Disarrayed granulosa cells in eosinophilic fluid?

Call-Exner bodies (granulosa-theca cell tumor of ovary)

13

Dysplastic squamous cervical cells with nuclear enlargement and hyperchromasia?

Koilocytes (HPV: predisposes to cervical cancer)

14

Enlarged cells with intranuclear inclusion bodies?

"Owl's eye" appearance of CMV

15

Enlarged thyroid cells with ground-glass nuclei?

"Orphan Annie's eyes" nuclei (papillary carcinoma of thyroid)

16

Eosinophilic cytoplasmic inclusion in liver cell?

Mallory bodies (alcoholic liver dz)

17

Eosinophilic cytoplasmic inclusion in nerve cell?

Lewy body (Parkinson's)

18

Eosinophilic globule in liver?

Councilman body (toxic or viral hepatitis, often yellow fever)

19

Eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells?

Negri bodies of rabies

20

Extracellular amyloid deposition in gray matter of brain?

Senile plaques (Alzheimer's dz)