Classic Labs/Findings 5 Flashcards Preview

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Flashcards in Classic Labs/Findings 5 Deck (25)
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1

Psammoma bodies?

Meningiomas, papillary thyroid carcinoma, mesothelioma, papillary serous carcinoma of the endometrium and ovary

2

Pseudopalisading tumor cells on brain biopsy?

Glioblastoma multiforme

3

RBC casts in urine?

Acute glomerulonephritis

4

Rectangular, crystal-like, cytoplasmic inclusions in Leydig cells?

Reinke crystals (Leydig cell tumor)

5

Renal epithelial casts in urine?

Acute toxic/viral nephrosis

6

Rhomboid crystals, positively birefringent?

Pseudogout (calcium pyrophosphate dihydrate crystals)

7

Rib notching?

Coarctation of aorta

8

Ring-enhancing brain lesion in AIDS?

Toxoplasma gondii, CNS lymphoma

9

Sheets of medium-sized lymphoid cells with scattered pale, tingible body-laden macrophages ("starry sky" histo)?

Burkitt's lymphoma (t[8;14] c-myc activation, assoc with EBV; "black sky" made up of malignant cells)

10

Silver-staining spherical aggregation of tau proteins in neurons?

Pick bodies (Pick's dz: progressive dementia, changes in personality)

11

"Soap bubble" in femur or tibia on x-ray?

Giant cell tumor of bone (generally benign)

12

"Spikes" on BM, "dome like" subepithelial deposits?

Membranous glomerulonephritis (may progress to nephrotic syndrome)

13

Stacks of RBCs?

Rouleaux formation (high ESR, plasma cell myeloma)

14

Stippled vaginal epithelial cells?

"Clue cells" (Gardnerella vaginalis)

15

"Tennis racket" shaped cytoplasmic organelles (EM) in Langerhans cells?

Birbeck granules (Langerhans cell histiocytosis or histiocytosis X: eosinophilic granuloma)

16

Thrombi made of white/red layers?

Lines of Zahn (arterial thrombus, layers of platelets/RBCs)

17

"Thumb sign" on lateral x-ray?

Epiglottitis (H. influenzae)

18

Thyroid-like appearance of kidney?

Chronic bacterial pyelonephritis

19

Tram-track appearance of capillary loops of glomerular BM on light microscopy?

Memrabnoproliferative glomerulonephriitis

20

Triglyceride accumulation in liver cell vacuoles?

Fatty liver dz (alcoholic or metabolic syndrome)

21

"Waxy" casts with very low urine flow?

Chronic end-stage renal dz

22

WBC casts in urine?

Acute pyelonephritis

23

WBCs that look "smudged"?

CLL (almost always B-cell)

24

"Wire loop" glomerular capillary appearance on light microscopy?

Lupus nephropathy

25

Yellowish CSF?

Xanthochromia (e.g. due to subarachnoid hemorrhage)