Classic Labs/Findings 4 Flashcards Preview

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Flashcards in Classic Labs/Findings 4 Deck (20)
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1

"Lead pipe" appearance of colon on barium enema x-ray?

Ulcerative colitis (loss of haustra)

2

Linear appearance of IgG deposition on glomerular BM?

Goodpasture's

3

Low serum ceruloplasmin?

Wilson's (hepatolentricular degeneration)

4

"Lumpy bumpy" appearance of glomeruli on IF?

Poststrep glomerulonephritis (immune complex deposition of IgG + C3b)

5

Lytic ("hole punched") bone lesions on x-ray?

Plasma cell myeloma

6

Mammary gland ("blue domed") cyst?

Fibrocystic change of the breast

7

Monoclonal Ab spike?

Multiple myeloma (IgG or IgA), MGUS (normal consequence of aging), Waldenstrom's (M protein = IgM), primary amyloidosis

8

Mucin-filled cell with peripheral nucleus?

Signet ring (gastric carcinoma)

9

Narrowing of bowel lumen on barium x-ray?

"String sign" (Crohn's)

10

Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis?

Granulomatosis with polyangiitis (Wegener's; c-ANCA positive) and Goodpasture's (anti-BM Abs)

11

Needle-shaped, negatively birefringent crystals?

Gout (monosodium urate crystals)

12

Nodular hyaline deposits in glomeruli?

Kimmelstiel-Wilson nodules (diabetic nephropathy)

13

Novobiocin response?

Sensitive: Staph epidermidis; resistant: Staph saprophyticus

14

"Nutmeg" appearance of liver?

Chronic passive congestion of liver due to right heart failure

15

"Onion skin" periosteal reaction?

Ewing's sarcoma (malignant round-cell tumor)

16

Optochin response?

Sensitive: Strep pneumoniae; resistant: Viridans strep

17

Periosteum raised from bone, creating triangular area?

Codman's triangle on x-ray (osteosarcoma, Ewing's sarcoma, pyogenic osteomyelitis)

18

Podocyte fusion or "effacement" on electron microscopy?

Minimal change dz (child with nephrotic syndrome)

19

Polished, "ivory like" appearance of bone at cartilage erosion?

Eburnation (osteoarthritis resulting in bony sclerosis)

20

Protein aggregates in neurons from hyperphosphorylation of protein tau?

Neurofibrillary tangles (Alzheimer's) and Pick's bodies (Pick's dz)