Classic labs/findings Flashcards Preview

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Flashcards in Classic labs/findings Deck (33):
1

Anti-centromere antibodies

CREST

2

Anti-histone antibodies

Drug-induced SLE -> hydralazine, INH, phenytoin, procainamide

3

Anti-mitochondrial antibodies

Primary biliary cirrhosis -> female, cholestasis, portal HTN

4

Anti-platelet antibodies

ITP

5

Anti-topoisomerase antibodies

Diffuse scleroderma

6

Boot-shaped heart on X-ray

Tetrology of Fallot, RVH

7

Branching gram-positive rods with sulfur granules

Actinomyces israelli

8

Brown tumor of bone

Hyperparathyroidism -> Osteitis fibrosa cystica

9

Circular grouping of dark tumor surrounding pale neurofibrils

Homer-Wright rosettes -> neuroblastoma, medulloblastoma, retinoblastoma

10

Decreased alpha-fetoprotein

Down syndrome or other chromosomal abnormality

11

Desquamated epithelium casts in sputum

Curshmann's spirals -> bronchial asthma -> whorled mucus plugs

12

Disarrayed granulosa cells in eosinophilic fluid

Call-Exner bodies -> granulosa-theca cells tumor of the ovary

13

Enlarged thyroid cells with ground-glass nuclei

Orphan Annie -> Papillary carcinoma of the thyroid

14

Eosinophilic cytoplasmic inclusion in the liver cells

Mallory bodies -> alcoholic liver disease

15

Eosinophilic cytoplasmic inclusion in the nerve cells

Lewy body

16

Eosinophilic globule in the liver

Councilman body -> toxic or viral hepatitis -> yellow fever

17

Eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells

Negri bodies of rabies

18

Hair on end -> crew cut on X-ray

Sickle cell, Beta-thalassemia

19

Granulomatous heart nodules

Aschoff bodies -> rheumatic heart disease

20

Hexagonal, double-jointed, needle-like crystals in bronchial secretions

Bronchial asthma -> Charcot Leyden crystals -> eosinophilic granules

21

Hypertension, hypokalemia, metabolic alkalosis

Conn's syndrome

22

Hypochromic, microcytic anemia

1) Iron deficiency anemia
2) Lead poisoning
3) Thalassemia

23

Iron-containing nodules in alveolar septum

Ferruginous bodies -> asbestosis

24

Large lysosomal vesicles in phagocytes, immunodeficiency

Chediak-Higashi -> no phagolysosome formation

25

Onion skin periosteal reaction

Ewing's sarcoma

26

Rhomboid crystals, positively birefringent

Pseudogout -> calcium pyrophosphate dihydrate crystals

27

Rib notching

Coarctation of aorta

28

Silver-staining spherical aggregation of tau protein in neurons

Pick bodies -> progressive dementia, changes in personality

29

Soap bubble in femur or tibia on x-ray

Giant cell tumor of bone -> benign

30

Thyroid-like appearance of kidney

Chronic bacterial pyelonephritis

31

Waxy casts with little urine flow

End-stage renal disease

32

Smudges WBCs

CLL (B-cell)

33

Wire loop glomerular capillary appearance on light microscopy

Lupus nephropathy