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Flashcards in Equations Deck (13):
1

Volume of distribution

Amount of drug in body/ plasma drug concentration

2

Half-life

(0.7 x Vd)/CL

3

Drug clearance

1) Rate of drug elimination/ plasma drug concentration
2) Vd x Ke (elimination constant)

4

Loading dose

LD = Cp x Vd/F (bioavailability)

5

Maintenance dose

MD = Cp x CL/F

6

Stroke volume

End diastolic volume - end systolic volume

7

Ejection fraction

SV/ end diastolic volume

8

Renal clearance

Cx=UxV/Px
1) Inulin/creatinine used for GFR
2) PAH used for effective renal blood flow

9

Renal blood flow

RPF/ (1-HCT)

10

Filtration fraction

GFR/RPF

11

Physiologic dead space

VT x (PaCO2 - PECO2)/PaCO2

12

Pulmonary vascular resistance

PVR = P (pulmonary artery) -P (left atrium)/ CO

13

Alveolar gas equation

PAo2 = PIO2 - (PaCO2/R)
PAo2 = 150- PaCO2/0.8