Flashcards in Clinical Epidemiology 4 - Risk: Basic Principles Deck (10)
Probability of some untoward event
Characteristics associated with an increased risk of becoming diseased
Period between exposure to a risk factor and the first manifestation of disease
A risk factor that is not a cause of disease is called a ______
Marker of disease
Determining how well a risk prediction tool correctly predicts the proportion of a group who would develop disease
How to measure calibration of risk prediction tool?
Estimated number to develop disease / observed number who developed disease.
Ratio close to 1.0 means well calibrated
The accuracy of a risk prediction tool to identify which individuals will or will not have the disease.
This measures how often (in a given pair of random individuals) the risk prediction score was higher for the person with the disease?
Concordance Statistic (C-Statistic)
A useless toss coin-like tool has c-statistic of 0.5
A perfect tool has C-Statistic of 1
Best predictor of future major diseases?
Existing minor disease