CNS disease in nursery pigs Flashcards Preview

Food Animal > CNS disease in nursery pigs > Flashcards

Flashcards in CNS disease in nursery pigs Deck (15):
1

List the five primary rule-outs for CNS disease in nursery pigs:

  1. Streptococcal meningitis
  2. Glasser's disease (Haemophilus parasuis)
  3. Edema disease
  4. Salt-poisoning
  5. Pseudorabies

2

Etiology of edema disease

E. coli

3

Pathophysiology of Edema Disease

E. coli adheres to gut fimbria (F-18ab) and produces toxin (EDP or Shiga-like toxin) which damages vascular endothelium in various tissues. May or may not produce enterotoxin leading to secretory diarrhea.

4

Lesions of edema disease

Edema of stomach, colon, eyelids.

5

Edema disease has non-specific neurological signs due to edema and necrosis of the ______.

Brain

6

Salt-poisoning/Water deprivation causes ___-osmolarity of the CNS.

Hyper

7

Rapid rehydration in salt-poisoning/water deprivation results in osmotic _____ of the brain.

swelling

8

If fibrin is noted upon necropsy in nursery pigs, think _____ or ____.

Glasser's (Haemophilus parasuis) or Strep

9

Upon necropsy of a neonatal pig, if you see edema of stomach and eyelids, think _____.

Edema disease

10

Diagnostic tests - 

Culture the meninges to detect ___ or _____. Culture the intestines for _____.

Meninges - Strep or H. parasuis

Intestines - E. coli

11

Upon histopathology of the brain, purulent meningitis makes you suspicious of ____ or _____.

Strep or H. parasuis

12

Upon histopathology on the brain, eosinophilic perivascular cuffing makes you suscpicious of ____.

Salt poisoning/Water deprivation

13

Upon histpath on the brain, if you see non-suppurative meningoencephalomyelitis, think ________.

Pseudorabies (PRV)

14

Vaccinations are present for these three CNS diseases:

  • Strep
  • H. parasuis
  • PRV (pseudorabies)

15

Antibiotics are only effective against CNS disease in nursery pigs if given _____.

Early