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Flashcards in Mycoplasma pneumonia Deck (15):
1

Etiology

Mycoplasma hypopneumoniae

2

Pathogenesis 

  • Colonizes airways
  • Inflammatory response
  • Decreased mucociliary clearance

3

Secondary infections with ____ and ____, and other pathogens are common.

Pasteurella multocida

Streptococcus suis

4

Is uncomplicated mycoplasma infection mild?

Used to be mild. However, today we can have minimally complicated mycoplasma (not a lot of co-infection), and still see severe clinical signs. This is may be due to doing a good job of elimination of infectious diseases in the industry as a whole. So end up with healthy pigs with non-specific immune stimulation. When Mycoplasma gets introduced, then those healthy, naive pigs, suffer more than a pig that has been exposed to more pathogens. 

5

Mycoplasma infection is a major contributer to this disease complex:

Porcine Respiratory Disease Complex (PRDC)

6

Majority of mycoplasma infections are complicated or uncomplicated?

Complicated

7

Clinical signs

  • Around the airways - more in the parenchyma of the lungs vs inside the airways: intersitial or peribronchiolar inflammatory response
    • Chronic, non-productive cough in grow/finish pigs (because nothing to cough up - nothing in airway)
    • Cough induced by exercise
  • Minimal febrile response
  • Minimal depression and anorexia
  • Modest suppression of growth rates and feed efficiency 

8

Lesions of mycoplasma pneumonia include ____ lobar consolidation and ______ lymphoid hyperplasia.

  • anterioventral lobar consolidation
  • Peribronchiolar lymphoid hyperplasia 

9

The cough in Mycoplasma pneumonia is ______ (spontaneous or induced).

Induced!

10

Diagnosis - culture is possible, but difficult becuase?

Mycoplasma hard to culture- easility overgrown by other bacteria.

11

Which diagnostic tool may be useful for population profiling?

Serology - looking at when population is seroconverting

12

Can you use PCR to diagnose?

Yes

13

Examples of antimicrobials for treatment in feed or water:

  • Lincomycin
  • Tetracyclines
  • Tylosin
  • Tiamulin

14

Control for M. pneumonia:

  • Vaccination
  • All-in, all-out
  • Segregated early weaning - may eliminate
  • Environmental management

15

Herd elimination may be possible with partial depopulation of ____ to ____ pigs and medication of _____ swine.

  • wean to finish
  • breeding swine