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Flashcards in CNS Infections and features Deck (9)
1

What are the oragnisms that cause acute pyogenic meningitis in different age groups?

Neonates - Ecoli and GBS

 

Infants and Kids = Strep pneumoa

 

Young adults - mini epidemics = Neisseria meningitisi

Elderly - STrep pneumo and Listeria Monocytogenes 

2

Clinical findings for acute purulent / pyogenic meningitis? 

 

CSF findings? 

HA, photophosbia, irritability, clouding of consciousness, neck stiffness

 

CSF -- cloudy, increased neutrophils, increased protein, decreased glucose 

3

What are the predisposing conditions for a brain abscess? 

Bacterial endocarditis 

congenital heart disease (RL shunt) 

chronic pulmonary sepsis with dental procesdures etc 

4

Presentation for abrain abscess? 

 

Pathology of brain abscess? 

Focal deficits and increased ICP

Lesions are discrete and see central pus and debris surrounded by Hyperemic margin or fibrous collagen capsule

+vasogenic edema 

 

5

What are other bacterial infections of the brain? 

Subdural Empyema = spread from skull or sinuses and can cause herniation or mass effect

 

Epidural Abscess - in association with osteomyeltis, can cause spinal cord compression 

6

What can myocabacteria in the CNS cause? 

 

what pathoogy would you see? 

TB meningitis (BASILAR!) or a tuberculoma

 

see ganulomas with multinucleated histiocytes with Acid Fast Vacilli stain 

see caseous necrosis 

7

Waht are the different forms of neurosyphilis? 

Meningovascular neurosyphillis = chronic meningitis with obliterative endarterities and perivascular plasma cell infiltrate (similar to TB with basilar meningitis + Vascular compromise like minit strokes

 

Parenchymatous - either general paresis of insane w/ brain atrophy and dementia OR Tabes Dorsalis which is damage to Dorsal Rooty sensory neurons of SC and loss of Deep Tendon Reflexes 

8

What do you see with viral meningoencephalitis? 

Parenchymal infection of the brain associated with meningeal inflammation

 

Perivascular and Parenchymal mononuclear infiltration

Neuronophagia and Microglial activation 

sometimes see viral incluseions 

9

What is the presentation of