codeine Flashcards
(21 cards)
morphine classification
opiates
indications for morphine
Acute, severe dull pain
unwanted affects of morphine 5
Nausea, vomiting, respiratory depression, constipation, confusion
routes of administration of morphine
oral
IV
subcutaneous
don’t exceed ?mg of morphine in 24hrs
100mg
contraindications for morphine 6
-Suspected head injury - masks symptoms
-Acute alcoholism
-Decreased respiratory reserve
-Hepatic/renal insufficiency
-Ulcerative colitis
-Hypersensitivity - asthma
classification of codeine
opiates
therapeutic activity of codeine
Analgesic for mild to moderate pain
when is codeine useful for dental pain?
when combined with other drugs
what is cocodamol
codeine and paracetamol
what is codydramol
dihydrocodeine and paracetamol
metabolism of codeine
Metabolised in the liver to form morphine which is responsible for the analgesic property
indications for codeine
can’t use NSAIDs
side effects of codeine
Nausea, hypotension, urticaria, respiratory depression, constipation
interactions of codeine 4
Alcohol, antipsychotics - increase hypotensive effect
Antihistamines, anxiolytics, hypnotics - sedative effect
special considerations for codeine
Diarrhoea, GI issues
codeine dose
mg
hrly
max
30-60mg
4-6hrly
240mg max in 24hrs
analgesic efficacy is expressed as what?
NNT
what is NNT
- The number of pt who need to receive the active drug for one to achieve at least 50% relief of pain compared with placebo over a 4-6hr treatment period
what does a lower NNT mean?
more effective
order the following from highest to lowest NNT
ibuprofen
codeine
cocodamol
paracetamol
Codeine, paracetamol, ibuprofen, cocodamol
