COPD Flashcards
(39 cards)
What is COPD?
Chronic Obstructive Pulmonary Disease (COPD) is a progressive, chronic inflammatory lung disease characterized by airflow limitation that is not fully reversible.
The inflammation causes slowly an obstruction to bronchioles and thereby a pulmonary emphysema.
What are the main symptoms of COPD?
Chronic cough, sputum production (especially in the morning), dyspnea (shortness of breath), wheezing, chest tightness, decreased exercise tolerance, fatigue due to poor oxygenation, frequent respiratory infections, weight loss, and decreased Spo2 % levels (increased risk for Co2-retention).
What are examples of COPD?
emphysema and chronic bronchitis.
What are the stages of COPD according to GOLD Criteria?
Stages include:
- Mild (Stage I): FEV1 ≥80%, may have no symptoms, winded with moderate exercise or walking upstairs.
- Moderate (Stage II): FEV1 50–79%, frequent stops to catch breath, coughing, wheezing and breathlessness.
- Severe (Stage III): FEV1 30–49%, shortness of breath worsens, frequent flare-ups or exacerbations that leads to hospitalization. Worsening symptoms.
- Very Severe (Stage IV): FEV1 <30% or <50% with respiratory failure, Low oxygen level, constant shortness of breath. Flare ups and exacerbation, can be life threatening.
What is the pathophysiology of Emphysema?
Emphysema develops when the alveoli are destroyed, causing them to merge into one large air sac, leading to decreased surface area for gas exchange and air trapping.
Since it doesn’t absorb oxygen as well as healthy alveoli, the blood gets less oxygen.
Emphysema also causes the lungs to stretch out, losing their elasticity. As a result, air remains trapped in the lungs, making breathing difficult.
Alveoli are destroyed, leading to fewer, larger air sacs
Decreased surface area for gas exchange
Air trapping and hyperinflation
Loss of lung elasticity
What are the clinical presentations of Emphysema?
‘pink puffers’ (normal oxygen levels, pursed-lip breathing), severe dyspnea, barrel chest from difficulty exhaling, leading to air trapping., weight loss, and decline in functional ability.
What is the pathophysiology of Chronic Bronchitis?
The condition causes inflammation in the lining of bronchial tubes, which are responsible for carrying air to and from the alveoli. Chronic bronchitis damages the cilia (the hair-like fibers lining the bronchial tubes), which help eliminate mucus.
As a result, it becomes more challenging to remove mucus, making you cough more and obstructs the airflow. That’s why people with chronic bronchitis develop mucus that stays for an extended period, sometimes up to two years. Other symptoms of chronic bronchitis are shortness of breath and coughing.
Inflammation of the bronchi
Increased mucus production and thickening of airway walls
Ciliary dysfunction
Airflow obstruction
What are the clinical presentations of Chronic Bronchitis?
‘blue bloaters’ (low oxygen levels, cyanosis, fluid retention), persistent productive cough with thick mucus esp in morning, and edema.
What is the primary cause of COPD?
Smoking is the primary cause of COPD.
What are other risk factors for COPD?
Long-term exposure to air pollutants, second-hand smoke, indoor cooking fuels, occupational exposure to dust, fumes, and chemicals from workplace, genetic predisposition (Alpha-1 antitrypsin deficiency) a rare genetic disorder that can cause COPD even in nonsmokers, and respiratory infections.
What are the main risk factors for emphysema?
Long-term smoking, genetic deficiency (Alpha-1 antitrypsin), and chronic respiratory infections.
What are the main risk factors for chronic bronchitis?
Smoking, recurrent respiratory infections, air pollution, and occupational irritants.
What are the pharmacological treatments for COPD?
Bronchodilators (e.g., albuterol, salmeterol) - Relax airway muscles, inhaled corticosteroids (e.g., fluticasone) - Reduce airway inflammation, combination inhalers, oral corticosteroids (short-term), and antibiotics for infections.
What are the non-pharmacological interventions for COPD?
Smoking cessation, pulmonary rehabilitation, exercise training, education, and breathing techniques to improve quality of life, oxygen therapy (if SpO2 <88%), PAP at night in cases of sleep apnea and COPD or CPAP or BiPAP CPAP or BiPAP can be consider in palliative phase of the disease for ventilation support, Lung Transplantation. Lung transplantation is a viable option for definitive surgical treatment of end-stage emphysema, Surgery: Bullectomy
What is bullectomy?
Bullectomy is a surgical option for select patients with bullous emphysema and can help reduce dyspnea and improve lung function.
What is lung volume reduction surgery?
Lung Volume Reduction Surgery. Lung volume reduction surgery is a palliative surgery in patients with homogenous disease or disease that is focused in one area and not widespread throughout the lungs.
What surgical options are available for COPD?
Bullectomy, lung volume reduction surgery, and lung transplantation.
What are the long-term treatments for COPD?
Maintenance bronchodilators, inhaled corticosteroids, two long-acting β2-agonists in the same inhaler, and lifestyle modifications.
What are the short-term treatments for COPD?
Rescue inhalers (SABAs) and oral corticosteroids during exacerbations.
What is CPAP?
Continuous Positive Airway Pressure (CPAP) is a device that pressurizes the air to a higher level than the air in the room,- delivering constant air pressure to - keep airways open, especially during sleep. - It prevents alveolar collapse and - improves oxygenation. Used in sleep apnea and acute exacerbations of COPD.
What is BiPAP? It’s Functions?
Bilevel Positive Airway Pressure (BiPAP) provides two levels of pressure: higher during inhalation (IPAP) and lower during exhalation (EPAP). It supports both breathing in and out and enhances ventilation in severe COPD.
What are the main aims for treating COPD?
To relieve symptoms, improve exercise tolerance and quality of life, prevent disease progression and exacerbations, and reduce mortality.
What are the prevention strategies for COPD?
smoking cessation, avoiding occupational/environmental irritants, vaccinations (influenza, pneumococcal), early treatment of respiratory infections, and regular follow-ups with a healthcare provider.