Rheumatic diseases Flashcards
(47 cards)
What are rheumatoid diseases?
Rheumatoid diseases are chronic inflammatory disorders, mostly autoimmune in nature, affecting the musculoskeletal system, especially synovial joints.
How are rheumatoid diseases classified?
They are classified under musculoskeletal disorders (MSDs) and often involve connective tissue, joints, and organs.
What does the musculoskeletal system consist of?
The musculoskeletal system allows body movements and consists of bones, muscles, joints, ligaments, tendons, and cartilage.
What are common features of rheumatic diseases?
Autoimmune reactions, inappropriate functioning of the immune system, inflammatory joint damages, and diseases of other supporting structures and organs. (connective tissues, vasculitis)
What medical specialties treat musculoskeletal disorders?
Medical specialties include orthopaedics, traumatology, rheumatology, and physiatry.
What is rheumatology?
Rheumatology is a narrow specialization field of internal medicine.
What are examples of rheumatoid diseases?
Rheumatoid Arthritis, Ankylosing Spondylitis, Arthritic Psoriasis, Reactive arthritis, Lyme disease, Muscle rheumatism, Infectious arthritis, Osteoarthritis, Gout, Sjögren’s Syndrome, Fibromyalgia.
Rare rheumatic diseases.
Polymyositis, Systemic Sclerosis, Mixed Connective Tissue Disease (MCTD), Vasculitis, and Lupus (SLE).
What is rheumatoid arthritis (RA)?
RA is a chronic autoimmune disease where the immune system attacks the synovial membrane, leading to joint inflammation, destruction, and potential disability.
What are the characteristics of rheumatoid arthritis?
RA is symmetrical, more common in women, and often affects small and medium joints.
What is a prerequisite for diagnosing rheumatoid arthritis?
A prerequisite for the diagnosis of rheumatoid arthritis is arthritis.
What are the signs and symptoms of rheumatoid arthritis?
inflammation in several joints, joint swelling, morning stiffness, tenderness during movement, fatigue, lack of appetite, mild fever, weight loss, and rheumatoid nodules.
Malpositions are possible in the later stages of the disease.
What joints are initially affected in rheumatoid arthritis?
Initially affects MCP, PIP, MTP joints, and wrists.
What are the cornerstones of treatment for rheumatoid arthritis?
Early diagnosis, long-term medication, rehabilitation, multi-professional care, and patient education & support.
What are the risk factors of rheumatoid arthritis?
Unknown cause, hereditary predisposition, smoking (primary environmental factor), more common in women, associated with increased cardiovascular risk.
What are the pharmacological treatments for rheumatoid arthritis?
DMARDs: Methotrexate, Sulfasalazine, Hydroxychloroquine; Glucocorticoids: Prednisolone (oral/injections); Cortisone joint injections; NSAIDs: Ibuprofen, Naproxen; Biologics if other medications dont help: Rituximab, Infliximab; Pain meds: Paracetamol, Tramadol; Calcium and vitamin D supplements (increased risk of osteoporosis)
What are the non-pharmacological treatments for rheumatoid arthritis?
Rehabilitation: Physiotherapy, occupational therapy; Exercise (including water aerobics); Heat/cold treatment, laser therapy, TENS (Transcutaneous Electrical Nerve stimulation); Underwater ultrasound therapy; Assistive devices (splints, supports); Dietician and psychosocial support; Surgery in severe cases.
What are the pharmacological treatments for rheumatoid diseases?
Same as RA: DMARDs, biologics, pain management (paracetamol, antidepressants, tramadol), NSAIDs (two different NSAIDs should not be used at the same time), muscle relaxants, glucocorticoids to reduce inflammation, antirheumatic medicines.
What are the non-pharmacological treatments for rheumatoid diseases?
Physiotherapy; Occupational therapy; Psychological support; Diet and weight management; Education and rehabilitation programs.
What are the short-term treatments for rheumatoid diseases?
Symptom relief (NSAIDs, cortisone).
What are the long-term treatments for rheumatoid diseases?
DMARDs, biologics, lifestyle changes, prevention of joint damage.
What are some examples of antirheumatic medicines?
Methotrexate, Sulfasalazine, Hydroxychloroquine, Leflunomide, Azathioprine
What is the typical onset time for antirheumatic medicines to take effect?
1-6 months
What are common side effects of antirheumatic medicines?
Nausea, stomach upset, rash, changes in blood counts, increased liver values, kidney changes