Stroke Flashcards
(67 cards)
What are strokes?
Strokes are focal neurological deficits (loss of function affecting a specific region of the nervous system) due to disrupted blood supply to the brain.
What are the main types of strokes?
The main types of strokes are Ischemic Stroke and Hemorrhagic Stroke.
What is an Ischemic Stroke?
An ischemic stroke occurs when something blocks blood flow to the brain, typically resulting from thrombosis or embolism.
Ischemic strokes can cause permanent brain damage and death.
What percentage of strokes are ischemic?
Ischemic strokes account for 80% of all strokes.
What is a Hemorrhagic Stroke?
A hemorrhagic stroke occurs when a blood vessel in the brain ruptures and bleeds. Divided into intracerebral and subarachnoid hemorrhage.
What percentage of strokes are hemorrhagic?
Hemorrhagic strokes account for 20% of all strokes.
What is an Intracerebral hemorrhage?
Intracerebral hemorrhage is characterized by bleeding into the brain parenchyma. May look like an ischemic stroke
What is a Subarachnoid hemorrhage?
Subarachnoid hemorrhage is bleeding in the space between the brain and its covering membranes, often caused by a ruptured aneurysm.
SAHs are commonly caused by head trauma and/or a ruptured brain aneurysm
Layers in brain
Your brain has three membrane layers or coverings (called meninges) that lie between your skull and your brain tissue. The outermost layer of your meninges is called the dura mater, the middle layer is the arachnoid and the layer closest to your brain is the pia mater. Subarachnoid hermorrhage happens when there’s bleeding below the arachnoid layer.
Risk factor, treatment and prognosis for SAH
Risk factors: Hypertension, use of blood thinner (Warfin)smoking and alcohol consumption, cocaine or meth use, Paralysis is rare.
Treatment: Surgery
Prognosis: With fast surgery patients usually recover well and risk for a new bleeding is low.
Intracerebral Versus Subarachnoid Hemorrhage
Subarachnoid
* Bleeding into subarachnoid
space
* Usually caused by aneurysm
rupture
* Stiff neck
* Photophobia (may be present in
both, but most common in SAH)
* “Thunderclap headache”: often
described as the worst headache
of the patient’s life
Intracerebral
* Bleeding into brain tissue
* Caused by arterial rupture
* Often presents like ischemic
stroke
* Focal neurological deficits
* Altered consciousness
* Nausea and vomiting
* Seizures due to irritation of brain
tissue
Atherosclerosis definition and characteristics
Atherosclerosis is a disease involving the buildup of plaque
in the arteries. When there is atherosclerosis in the cerebral
arteries, the risk for stroke or TIA is increased.
Arterial plaque composed of fat and cholesterol are very
unstable, meaning that they rupture more frequently. The
presence of plaque fragments causes blood to clot, which
can cause blockages.
o This happens because collagen is exposed to blood, which
activates platelets, causing coagulation of the blood.
o This is also due to the body’s inflammatory response, meaning that
immune cells such as macrophages are attracted to the site of
rupture. These cells help to stabilize the clot.
What are the risk factors for strokes?
Hypertension,
atrial fibrillation - The atria are fibrillating and not beating in a coordinated way → Blood in the atria becomes stagnant and can form clots. Atrial fibrillation can lead to stasis of blood in the left atrium → This allows blood clots to form → If a piece of clot breaks off and travels to an artery in the brain, it can block the blood flow through the artery, causing a stroke.
type 2 diabetes (3x at risk),
smoking(2x at risk), alcohol, obesity, inactivity. Approx. 20% of strokes are caused by these.
High cholesterol, atherosclerosis, and carotid artery disease
age, gender -After the age of 55 stroke risk doubles for every decade a person is alive, gender - Men under 75 y have double risk for stroke compared to women, who usually get stroke older and women over 85 y have bigger risk for stroke than men.
family history, and prior strokes.
What is TIA?
Transient Ischemic Attack (TIA): Temporary stroke symptoms (usually <1 hour), without evidence of acute cerebral infarction are termed a transient ischemic attack (TIA)
What are common causes of ischemic strokes?
Common causes include atherothrombotic occlusion of large arteries
Embolic Infarction: Cerebral embolism, in which blood clot forms somewhere else and travels to the brain.
Presents similarly to atherothrombotic occlusion of large vessels. Cardioembolic stroke is diagnosed when no other
apparent cause is found.
Lacunar Infarction: Nonthrombotic occlusion of smaller, deep cerebral arteries. Often occurs in patients with DM2 and hypertension. Lesion is very small (generally <1.5 cm in diameter)
Hemodynamic Stroke: Proximal arterial stenosis with hypotension that decreases cerebral blood flow in arterial
watershed zones (ie, stroke is caused by hypoperfusion, or decreased blood flow through the vessels. Involves systemic (blood loss) causes or structural (stenoses) causes.
- Thrombotic stroke occurs when blood clots form in cerebral arteries.
- Embolic stroke occurs when blood clots form elsewhere in the
body and migrate to the cerebral arteries
Causes of hermorrhagic strokes.
Brain aneurysms, Brain tumors, Moyamoya disease, Cerebral amyloid angiopathy, Head injuries, COVID-19, Ischemic strokes that cause bleeding during or after the stroke
What are the symptoms of an Ischemic Stroke?
headache possible vomiting, weakness/paralysis, often on one side of the body, confusion, vision loss, slurred speech or inability to speak, dizziness, seizures, difficulty walking, coordination problems in the arms, irregular breathing, coma.
What are the symptoms of a Hemorrhagic Stroke?
severe headache, vomiting, unconsciousness, and seizures. Intracerebral hemorrhage.
What are the symptoms of a Subarachnoid hemorrhage?
Sudden severe headache, stiff neck, light sensitivity, vomiting, seizures, eye sensitivity (photophobia). and decreased consciousness.
Signs of brain aneurysm
Pain surrounding the eye, Changes in your vision, Dilated pupils, Weakness or numbness on one side of your body, Loss of hearing or trouble with balance, Seizures, Trouble with memory
What percentage of stroke patients experience depression?
30-50% of stroke patients experience depression. Its common during the first year after the stroke.
What factors increase the risk of depression after a stroke?
disabilities affecting functional ability, cognitive impairment, prior depression before stroke, severity of stroke, and anxiety.
Depression in acute phase
In the acute phase (1-3 weeks after the stroke), depression can be caused by changes in the brain. This type of depression usually disappears during the first month after the stroke without any special treatment.
Depression is common also among spouses!