Kidney Diseases Flashcards
(67 cards)
Cornerstones in the care of chronic kidney failure patients
Effective blood pressure control, Protein and phosphate restriction in diet, Good glucose control in diabetics, Correction of acidosis and anemia, Vitamin D supplementation, Regular nephrology visits (every 6–12 months), Avoiding nephrotoxic medications and preventing infections, Smoking cessation.
What is a kidney?
Kidneys are bean-shaped organs vital for filtering waste and excess water from the blood, producing urine, and maintaining the body’s fluid and electrolyte balance.
What are the functions of the kidneys?
- Remove waste products and drugs
- Regulate fluid, electrolyte, and acid-base balance (together with the lungs)
- Control red blood cell production (formation of erythropoietin)
- Control blood pressure (via hormone release)
- Regulate calcium and phosphate metabolism
- Production of vitamin D
Name parts of the kidney.
Cortex, medulla, renal pelvis, ureter, calyces, nephrons
What are the 8 vital signs?
- Body Temperature
- Pulse Rate
- Respiration Rate
- Blood Pressure
- Blood Oxygen (SpO2)
- Blood Glucose Level
- Urine Output
- Weight
What is AKI (Acute Kidney Injury) and how is it identified?
AKI is a sudden decline in kidney function within hours or days, detected by a rise in creatinine (Cr) and/or decrease in urine output.
What are the signs and symptoms of AKI?
- Low urine output
- Increased serum creatinine
- Weight gain
- Swelling, SOB, pulmonary edema
- Metabolic acidosis
- Pleural fluid collection
- Hyperkalemia, uremia, coagulation issues
It can occur without symptoms.
What are the 3 classifications of AKI?
The three classifications of AKI (RIFLE) are:
1. Risk
2. Injury
3. Failure
4. Loss (Outcome)
5. End-Stage Renal Disease (ESRD)
-The severity criteria of AKI are defined on the basis of the changes in sCr or UO where the worst of each criterion is used. Page 18 and 19 for the picture in detail.
What is the normal range of creatinine levels in men?
Men: 0.7–1.3 mg/dL (61.9–114.9 µmol/L)
What is the normal range of creatinine levels in women?
Women: 0.6–1.1 mg/dL (53–97.2 µmol/L)
Women often have a lower creatinine level than men. This is because women often have less muscle mass than men. Creatinine level varies based on a person’s size and muscle mass.
Women often have a lower creatinine level than men due to having less muscle mass.
What is the central cause in AKI?
The central cause is the sudden decrease in glomerular filtration rate (GFR).
What are the central problems associated with AKI?
Fluid balance disturbances, metabolic acidosis, high potassium level, uremia (buildup of urea and other waste products in the body) , and coagulation problems.
What are pre-renal factors causing AKI?
Hypoperfusion (reduced blood flow to the kidney) of the kidneys via condition like hypotension, hypovolemia, sepsis, surgery, and low cardiac output.
What are renal factors causing AKI?
Infections and nephrotoxic drugs.
What are post-renal factors causing AKI?
Obstruction, such as from prostate issues or tumors.
What changes in serum levels occur in acute kidney injury?
Serum creatinine, urea, potassium, and phosphate levels are elevated, while calcium levels are lowered.
Which is more precise for assessing kidney function: GFR or serum creatinine?
GFR is more precise than serum creatinine.
What is the quickest way to check for kidney issues?
Protein in urine.
What is oliguria?
is the medical term for low urine output or peeing less than you expect.
What is proteinuria?
Protein in urine; an early sign of kidney damage.
What are the types of proteinuria?
Transient -Occurs with dehydration, stress, heavy exercise, fever & subsides on its own.
Orthostatic - Loses protein via urine only while standing and never while sleeping.
Persistent - consistent presence of protein in urine from kidney disease, diabetes and high BP.
What are the symptoms of proteinuria?
Often asymptomatic, but may include frequent urination, shortness of breath, nausea, vomiting, tiredness, lack of appetite, frothy, foamy or bubbly urine, edema, muscle cramping at night, and puffiness around the eyes especially in the morning.