Cornea and Sclera Part I Flashcards

(32 cards)

1
Q

what is the corneal epithelium?

A

stratified nonkeratinized squamous epithelium

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2
Q

what makes up 90% of the corneal thickness?

A

corneal stroma

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3
Q

what is corneal dystrophy?

A

axial lipid deposition

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4
Q

what is pigmentary keratitis?

A

pigment from limbal stem cells

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5
Q

what makes up the fibrous tunic of the eye?

A

cornea
sclera
limbus

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6
Q

what is thee limbus?

A

junction between cornea, sclera, conjunctiva

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7
Q

what innervates the cornea?

A

ophthalmic branch of trigeminal nerve: CN V
concentrated in epithelium and just below

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8
Q

is corneal epithelium hydrophobic or hydrophilic?

A

hydrophobic

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9
Q

how thick is the corneal epithelium in a dog or cat?

A

25-40 micrometers

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10
Q

what are the layers of the corneal epithelium?

A

single layer of basal cells
2-3 layers of intermediate cells
2-3 layers of superficial cells

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11
Q

what is the life cycle of basal cells?

A

transform, migrate, sloughed in 7-10 days

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12
Q

what are the three components of thee corneal stroma?

A

cells: mostly keratocytes
ground substance
collagen fibrils

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13
Q

what does ground substance do?

A

regulate hydration
maintain collagen spacing

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14
Q

what are collagen fibrils arranged for in corneal stroma?

A

to limit light scatter

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15
Q

how thick is descemet’s membrane?

A

10-15 micrometers
thickens with age

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16
Q

what are the junctions between cells in corneal endothelium?

A

macula occludens

17
Q

what regulates corneal hydration?

A

active maintenance of osmotic gradient between corneal stroma and aqueous

18
Q

can corneal endothelium divide and replicate?

19
Q

is fluoroscein staining hydrophobic or hydrophilic?

A

hydrophilic and lipophobic

20
Q

what filter should you use for fluoroscein staining?

A

cobalt blue filter

21
Q

what will fluoroscein staining not stain?

A

descemet’s membrane
epithelium
edematous tissue
melting tissue

22
Q

what does rose bengal staining stain?

A

areas with insufficient tear film

23
Q

what is a dermoid?

A

congenital
normal tissue growing in abnormal area

24
Q

what does edema look like?

A

white lesion
mottled appearance
diffuse/indistinct borders

25
when does corneal dystrophy show up?
early in life
26
who commonly gets endothelial degeneration/decompensation?
older small-breed dogs pit bulls
27
what is pigmentary keratitis a response to?
chronic irritation
28
what is pannus?
chronic superficial keratitis bilateral
29
does pannus usually respond well to treatment?
yes
30
what is pathognomonic of feline herpetic keratitis?
dendritic corneal lesions
31
what does feline eosinophilic keratoconjunctivitis look like?
fleshy infiltrates white caseous plaques
32
how are feline corneal sequestrums treated?
keratectomy +/- graft medical management usually unrewarding