Corpus Luteum Formation and Luteolysis

Question 1

transient structure

Answer 1

not there for very long

Question 2

corpus hemorrhagicum

Answer 2

transient structure between follicle and corpus luteum

Question 3

when no longer a follicle, granulosa cells become

Answer 3

large luteal cells

Question 4

when no longer a follicle, theca cells become

Answer 4

small luteal cells

Question 5

corpus luteum contains what cells

Answer 5

large luteal cells
small luteal cells

Question 6

what type of feedback is progesterone

Answer 6

negative

Question 7

what hormone can CL only produce

Answer 7

progesterone

Question 8

process to progesterone

Answer 8

cholesterol–> pregnenolone–>progesterone

Question 9

the four main jobs of progesterone

Answer 9

1. negative feedback
2. targets uterus
3. stimulate endometrium
4. stimulate mammary gland

Question 10

what happens when progestogen targets the uterus

Answer 10

• inhibit effect on uterus so it can’t contract
• keep baby inside

Question 11

what happens when progestogen has a stimulate effect

Answer 11

cause endometrium to thicken and increase secretion of mucus

Question 12

what 2 hormones regulate process of luteolysis

Answer 12

oxytocin
PGF2alpaha

Question 13

what gonadotropin is used in CLs

Answer 13

LH

Question 14

what moves cholesterol into mitochondria

Answer 14

P450sc

Question 15

what is luteolysis

Answer 15

disintegration or decomposition of the CL

Question 16

lysis

Answer 16

decomposition

Question 17

what does luteolysis decreases

Answer 17

progesterone levels

Question 18

as CL decreases, progesterone

Answer 18

decreases

Question 19

location of oxytocin

Answer 19

local

Question 20

oxytocin target

Answer 20

uterus

Question 21

when uterus is targted by oxytocin, what is made

Answer 21

PGF2alpaha

Question 22

location of PGF2alpha

Answer 22

local

Question 23

PGF2alpaha target

Answer 23

CL

Question 24

what doesPGF2alapha trigger

Answer 24

lutolysis

Question 25

what are three outcomes in the luteal cell from lutolysis

Answer 25

1. PGF2alapha binds to receptor 2. calcium moves into cell 3. protein kinase C produced

Question 26

what happens when PGF2alpaha binds to receptor

Answer 26

opens calcium channels

Question 27

when calcium is in the luteal cell, what occurs

Answer 27

apoptosis

Question 28

apoptosis

Answer 28

cell death - in luteal cell case, triggered by calcium

Question 29

if fetus is present, what is not made

Answer 29

PGF2alapha

Question 30

macrophages

Answer 30

- break down and re-use luteal cells (phagocytize)

Question 31

what is present in the CL at the time of regression

Answer 31

macrophages lymphocytes

Question 32

what do lymphocytes produce

Answer 32

cytokines (proteins)

Question 33

what is the job of cytokines

Answer 33

activate macrophages

Question 34

what does cytokines inhibit

Answer 34

progesterone synthesis

Question 35

over time, what happens to the CL

Answer 35

disappears and leaves a corpus albican behind

Question 36

characteristics of corpus albican

Answer 36

white scar like connective tissue

Question 37

what are the two outcomes a dominant follicle can go trough

Answer 37

atresia or ovulation

Question 38

what are the process/outcomes after ovulation

Answer 38

ovulation-->corpus hemorrhagicum-->corpus luteum