Flashcards in Crohn's disease Deck (16):
what are the 2 causes of idiopathic inflammatory bowel disease (IBD)?
Crohn's disease and ulcerative colitis
when is the peak onset of IBD?
15-30 years old
what increases risk of crohn's disease?
which disease always affects the illeum and colon?
what disease always includes the rectum and almost always the colon?
what disease is continuous within the colon?
what disease is discontinuous in the GI tract?
which disease is hematochezia common?
which disease rarely has intestinal granulomas, strictures, and fistulas?
which disease includes the upper GI tract?
What type of inflammation is present in Crohn's disease?
what type of inflammation is present in ulcerative colitis?
what percentage of patients show extra-intestinal manifestations?
what is the etiology of IBD?
inappropriate inflammatory response to intestinal microbes in a genetically susceptible host
what are the genetic factors related to IBD?
1. nucleotide oligomerization domain 2 (NOD2)
2. interleukin-23-type 17 helper T-cell (Th17) pathway
3. autophagy genes