CSF Disorders Flashcards

1
Q

you shouldn’t drain more than __ml of CSF in a lumbar puncture

A

30

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2
Q

upper limit of normal for CSF pressure?

A

15mmHg

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3
Q

a CSF pressure of >__mmHg is abnormally high

A

20

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4
Q

average CSF pressure is __mmHg

A

10

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5
Q

how much CSF is made and absorbed per day?

A

a pint

a pint

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6
Q

what drug is very effective at reducing ICP

A

acetazolamide

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7
Q

absorption of CSF is driven by….

A

ICP

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8
Q

physical functions of CSF?

A

buoyancy

accompanies physical changes in the head

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9
Q

weight of the brain is…

A

1.5kg

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10
Q

fluid trapped in spinal cord is called…

A

syringomyelia

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11
Q

a child with hydrocephalus from birth’s phenotype is..

A

an unusually large head
thin shiny scalp with visible veins
bulging fontanelle
downward looking eyes

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12
Q

babies with hydrocephalus will have what problems?

A
poor feeding
irritability
vomiting
sleepiness
muscle stiffness and spasm in lower limbs
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13
Q

2 types of hydrocephalus?

A

obstructive

communicating

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14
Q

why do you get papilloedema?

A

optic nerve is an extension of the CNS and has meninges around it thus contains CSF

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15
Q

acquired causes of paediatric hydrocephalus?

A

haemorrhage
infection ie post meningitis
trauma
tumour

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16
Q

a child with congenital hydrocephalus will have it for life T or F

A

T

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17
Q

how can subarachnoid haemorrhages cause hydrocephalus?

A

the blood blocks up the arachnoid granulations

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18
Q

shunt complications?

A
overdrainage
underdrainage = blockage
infection
seizures
intracerebral haemorrhage
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19
Q

symptoms of a blocked shunt?

A

headache
vomiting
lack of upgaze in adults
papilloedema

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20
Q

Ix and Tx of a blocked shunt

A

CSF sample to microbiology

CT head

21
Q

name the triad that presents in normal pressure hydrocephalus?

A

ataxia
memory decline
incontinence
(basically get dementia)

22
Q

causes of NPH

A
idiopathic
SAH (subarachnoid haemorrhage)
meningitis
trauma
craniotomy
23
Q

what does the ataxia in NPH present like?

A

a broad based, shuffling gait

24
Q

Ix of NPH

A

CT/MRI
tracer diffusion studies
ICP measurement
tap test lumbar puncture

25
Tx of NPH
VP shunt
26
who gets IIH?
young overweight females
27
what conditions are associated with IIH?
``` obesity sleep aponoea hypothyroid addisons lupus ```
28
symptoms of IIH
headaches | visual field loss from papilloedema
29
signs of IIH ?
papilloedema constricted visual fields loss of visual acuity
30
LP pressure of someone with IIH would be...
>25mmHg (HIGH)
31
IIH is normal on imaging T or F
T
32
Tx of IIH
``` treat underlying cause diuretics lumbar puncture VP/LP (lumbar-peritoneal) shunt weight loss ```
33
LP shunt complications
blockage infection nerve root irritation subdural haemorrhage
34
what is an orthostatic headache?
a headache present on standing up that is relieved when lying down
35
symptoms of SIH
``` orthostatic headaches neck/upper back/arm pain visual field defects dizziness muffled hearing ```
36
in IIH the ventricles are normal size T or F
T
37
causes of SIH
idiopathic collagen disorders dural diverticula (looks really thick) trauma
38
"fat girl off school for years with headaches and has papilloedema" could be...
IIH
39
SIH Tx
conservative | surgery
40
drug Tx of mild IIH
acetazolamide | diuretic
41
SIH Ix
MRI | lumbar puncture
42
syringomyelia classic presentation?
``` sensory loss - cant feel pain loss of limb reflexes involuntary movements muscle wasting clawed hands ```
43
in a patient with persisting spine and limb symptoms ___ should always be considered
syringomyelia
44
early features of syringomyelia?
hyperhidrosis
45
hindbrain hernias are a form of...
syringomyelia
46
main symptoms of a hindbrain hernia
headaches following valsalva visual disturbances ear disturbance sometimes papilloedema
47
sleep apnoea is a common problem in those with...
hindbrain hernias
48
syringomyelia Tx
open up CSF channels via craniovertebral decompression drain syrinx cavity lower CSF pressure
49
where can CSF fluid be diverted to if there is too much in the subarachnoid space?
pleural cavity | peritoneal cavity