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RUVM Pharmacology > CV2 > Flashcards

CV2 Flashcards

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1
Q

Class 1A

A

Na Channel Blocker

Prolonged Action potential

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2
Q

Class 1B

A

Na Channel Blocker

Shortened Action potental

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3
Q

Class 2

A

Beta blocker

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4
Q

Class 3

A

K Channel Blockers

Prolongs refractory period without decreasing conductory velocity

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5
Q

Class 4

A

Ca channel blockers

Blocks entry of Ca

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6
Q

What are the Class 1A drugs

A

Quinidine

Procainamide

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7
Q

What are the class 1B drugs

A

Lidocaine

Mexilitine

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8
Q

What are the class 2 drugs

A 
Beta blockers
Esomol
Atenolol
Propranolol
Metaprolol
Carvedilol
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9
Q

What are the class 3 drugs

A

K channel blockers
Sotalol
Amiodarone

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10
Q

What are the class 4 drugs

A

Diltiazen

Magnesium Sulfate IV

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11
Q

Ventricular drugs

A 
Quinn Eats Anna's Pretty Donuts Daily
Quineline
Esmolol
Atenolol
Propranolol 
Diltiazem
Digoxin
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12
Q

Supreventricular drugs

A 
Peggy Licks Megans Stolen Apple Meusem
Procainamide
Lidocaine
Mexilitine
Sotalol
Amiodarone
Magnesium Sulfate IV
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13
Q

DOC for supraventicular arrythmyias in horses

A

Quinidine

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14
Q

DOC for supraventrical arrythmias

A

Diltiazem

Quinn eats anna DONUTS daily

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15
Q

DOC for ventricular

A

Lidiocaine

Peggy LICKS megans stolen apple meusum

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16
Q

Quinidine

A

Class 1A Na channel blocker
Prolong action potential
DOC for supra in horses

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17
Q

Procainamide

A 
class 1A Na blocker
Prolong AP
Ventricular
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18
Q

Lidocaine

A

Class 1B Na
SHortens AP
DOC for venticular

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19
Q

Mexilitine

A

CLass 1B Na
Shorten AP
ventricular

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20
Q

What are Class 2 non selective

A

esmolol
atenolol
metaprolol

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21
Q

MOA of CLass 2

A

Beta blockers

Inhibit effects of catecholamines on heart

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22
Q

If your putting a patient on CLass 2…what do they need

A

a stable heart

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23
Q

Propranolol

A

Class 2 beta blocker
non selective beta antagonist
supraventricular —pretty
Quinn eats anna pretty donuts daily

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24
Q

Esmolol

A

Class 2 beta blockers
Selective beta 1
Supraventricualr
ultra short acting

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25
Atenolol
Class 2 beta blocker Selective beta 1 Supraventricular
26
Metaprolol
Class 2 beta blocker | Selective bera 1 antagonist
27
Carvedilol
Class 2 beta blocker non selective beta antagonist selective alpha 1 antagonist
28
What are the class 3
Sotalol | Amiodarone
29
Both class 3 drugs treat
ventricular Peggy licked megans STOLEN APPLE meusem Sotalol Amiodarone
30
Sotalol
Class 3 K blocker non selective beta blocker Ventricular Peggy licked megans STOLEN apple meusum
31
Amiodarone
Class 3 K blocker Ventricualr Peggy licked megans stolen APPLE meusum viruoisly
32
What are the class 4 drugs
Diltiazem | Mg Sulfate IV
33
Which class 4 drug tx ventricular arrthymias
vnszium Sulfate IV
34
What class 4 drug treats supraventricular
Diltiazem | DOC
35
Diltiazem
Class 4 Ca channel blocker DOC supraventricular Oral may be toxic
36
Magnesium Sulfate IV
Class 4 ca channel blocker | Tx refractory ventricular arrhythmias
37
What do ACE inhibitors inhibit?
Inhibit angiotensin coverting enzyme Inhibit angiotension 2 synthesis Inhbit aldosterone Increase vasodilator
38
What is the goal of an ACE inhibitor
Vasodilate
39
Enalapril is a what?
ACE inhibitor
40
Benazepril
ACE inhibitor | Longer acting than Enalapril
41
Goal of Phosphodiesterase Inhibitor?
Nitrooxide mediated vasolation
42
What drug is a phosphodiesterase innhibitor that vasodilates?
Sidenafil
43
What is the DOC for pulmonary hypertension?
Sidenafil
44
Nitrates are contraindicated with what vasodilator
Sidenafil
45
Sidenafil MOA
phosphodiaesterase innhibitor | NO mediated vasodilation
46
Sidenafil
Phosphodiesterase inhibitor NO mediated vasodilation DOC pulmonary hypertension Contraindicated with concurrent nitrates
47
What are the direct acting vasodialtors
Nitrates | Hydralazine
48
What are the direct acting vasodilating nitrates?
Nitroprusside | Nitroglycerine
49
MOA of Nitrates
Increased NO formation | direct acting arteriole & venous vasosilation
50
What drug directly vasodilates BOTH arterioles & venous
Nitrates | Nitroprusside & Nitroglycerine
51
What drug directly vasodilates arterioles?
Hydralazine
52
MOA of Hydralazine
Increased local PGI2 cocentration | Directly vasodilates arterioles
53
What do you use to treat a true hypertension crisis?
Direct acting vasodilators | Nitrates & hydralazine
54
Hydralazine is contraindicated with what disease
renal disease ... for once its not cats holy fuck
55
Role of Ca channel blockers regarding vasodilation
Reduce systemic blood pressure
56
How to Ca channel blockers reduce systemic blood pressure
decrease peripheral resistance | decrease afterload
57
What are the Ca Channel blocker vasodialtors
Amlodipine
58
MOA o Amlodipine
inhibits influx of extracellular Ca --> dilation of coronary & systemic arteries
59
Amlodipine is the DOC for??
Hypertension in Cats!! meowwwwww
60
What do angiotension 2 antagonist do?
vasodilate!
61
What are the angiotension 2 antagosit vasodilators
Losartan
62
MOA of Losartan
Angiotension 2 receptor competitive antagonist
63
What is Losartan used to treat?
Anti-hypertensive adjucant therapy | so i guess nothing just like prevention

RUVM Pharmacology (5 decks)

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