D5 - low omega-6/omega-3 ratio for reducing inflammation Flashcards
What are seed oils high in omega-6 polyunsaturated fat linked to?
Seed oils high in omega-6 polyunsaturated fat (PUFA) linoleic acid (LA) are linked to inflammation
What does dietary LA increase
contributing to health issues?
What impact does LA have on inflammation and cardiovascular health?
LA induces an inflammatory environment
What is the AA-independent pathway of inflammation associated with omega-6 seed oils?
The AA-independent pathway of inflammation with omega-6 seed oils leads to oxidized linoleic acid metabolites (OXLAMs).
How do marine omega-3s counteract inflammation caused by AA metabolism?
Marine omega-3s inhibit inflammation caused by AA metabolism
What benefits do EPA and DHA
found in omega-3s
What are dietary omega-3 fatty acids associated with in cardiovascular and chronic diseases?
Dietary omega-3 fatty acids are associated with lower inflammation and endothelial activation in cardiovascular and chronic diseases.
Which omega-3 PUFA is particularly effective in reducing cytokine-induced endothelial leucocyte adhesion molecules?
DHA (docosahexaenoic acid) is particularly effective in reducing cytokine-induced endothelial leucocyte adhesion molecules.
What do omega-3 PUFAs reduce
inhibiting atherosclerosis?
What is the relationship between omega-3 index and inflammation in peripheral arterial disease patients?
The omega-3 index is inversely related to inflammation in peripheral arterial disease patients.
What happens when the omega-6/3 ratio decreases?
Decreasing the omega-6/3 ratio reduces the inflammatory response; studies suggest that replacing omega-6 with omega-3 reduces inflammation.
What is a low omega-6/3 ratio associated with in animal studies?
A low omega-6/3 ratio is associated with lower triglycerides
What contribution do omega-6 (AA) eicosanoids and cytokines make to inflammation?
Omega-6 (AA) eicosanoids and cytokines contribute to inflammation; NSAIDs inhibit these metabolites.
How do omega-3 PUFAs act in terms of inflammation?
Omega-3 PUFAs act as anti-inflammatory agents
What may consuming omega-6 seed oils have adverse effects on
and what can omega-3 supplementation benefit?
