Data - Hepatobiliary Flashcards Preview

3rd Year > Data - Hepatobiliary > Flashcards

Flashcards in Data - Hepatobiliary Deck (11):
1

How much do ALT and ALP rise in pathology?

ALT = 10 fold increase
ALP = 3 fold increase

2

ALT is raised 10 fold.
ALP is raised less than 3 fold.

Hepatocellular injury

3

ALT is raised less than 10 fold.
ALP is raised 3 fold.

Cholestasis

4

Raised ALP and GGT?

Cholestasis with biliary tree involvement

5

Isolated ALP?

Non-hepatobiliary cause
Bony metastases
Fracture
Vit D deficiency

6

How to assess synthetic function of liver?

Serum bilirubin
Serum albumin
Serum glucose
Prothrombin time

7

Raised unconjugated bilirubin?

Haemolysis
Impaired hepatic uptake (drugs, CCF)
Impaired conjugation (Gilbert's)

8

Raised conjugated bilirubin?

Hepatocellular injury
Cholestasis

9

Lowered albumin?

Liver dysfunction - cirrhosis
Inflammatory response
Nephrotic syndrome, or other excessive loss of albumin

10

Cholestasis bloods?
ALP; ALT; GGT; Bilirubin

ALT - Slightly raised
ALP - very raised
GGT - very raised
Bilirubin - very raised

11

Acute hepatocellular injury bloods?
ALP; ALT; GGT; Bilirubin

ALT - Very raised
ALP - slightly raised
GGT - slightly raised
Bilirubin - slightly or very raised