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Flashcards in Definitions #2 Deck (20)
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1

TB

chronic disease caused by airborne Mycrobacterium tuberculosis

2

HIV

a retrovirus that invades and inactivates T-cells + causes AIDS

3

HIV-1

most prevalent HIV subtype, major aerological agent of AIDS

4

HIV-2

less virulent than HIV-1 but still causes AIDS

5

AIDS

the last stage of HIV, when the immune system is too weak to fight infection so they develop certain defining symptoms and illnesses
e.g. recurrent Pneumonia

6

Is there a TB vaccine?

Yes: Bacille Calmette Guerin

7

ART is more successful if...

... it is started before CD4 count falls below 350 cells/mm^3 of blood (WHO recommended threshold)

8

The global fund

a partnership organisation designed to accelerate the end of AIDS, TB + Malaria epidemics

9

Filarial diseases

group of tropical diseases caused by parasitic round worms (nematodes) and their larvae

10

Onchocerciasis

a.k.a. river blindness
main filarial disease + is transmitted by black flies

11

Lymphatic filariasis

main filial disease that has two types:
1) Bancroftian filariasis
2) Brugian filariasis

12

List the NTD covered on this course. (6)

~ Lymphatic filariasis
~ Onchocerciasis
~ Dengue fever
~ Schistosomiasis
~ Leishmaniasis
~ Chagas disease

13

Bancroftian filariasis

common in urban areas + transmitted by *Culex*, Anopheles and Aedes mosquitoes

14

Brugian filariasis

rural disease mainly transmitted by Manosonia mosquitoes

15

Why are tropical diseases no longer tropical?

~ global movement of pathogens through human travel
~ climate change
~ human encroachment of natural habitats

16

Name the big three.

BACTERIA: Tuberculosis (airborne)
VIRUS: HIV - sexual transmission
PROTOZOAN: Malaria - vector borne

17

Neglected tropical diseases

Diseases related to poverty and largely absent from the global public health agenda

18

What is the importance of NTDs?

~ Individually there isn't much but together (e.g. a group of 13) there is as DALYs = 56.6 million
~ poorest people suffer, they can't afford treatment so not much money in it so not much research done

19

What is the DALYs of Maleria?

46.5mil

20

OCP

a.k.a. onchocerciasis control programme
~ based on killing the blackfly vectors via aerial insecticide spraying over rivers/streams