dementia symposium Flashcards

(30 cards)

1
Q

what are the frontal lobe symptoms of dementia

A

abnormal- behaviour

impaired judgement, abstract reasoning, strategic planning, emotional restraint, loss of appetite and continence.

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2
Q

what are the parietal lobe symptoms of dementia

A

impairment of visuospatial skills, integration and sensory inputs.

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3
Q

what are the medial temporal lobe, hippocampus, amygdala and limbic system symptoms of dementia

A

disorder of memory and hallucinations

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4
Q

what are the temporal neocortex symptoms of dementia

A

recepetive dysphasia (speech)

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5
Q

what are the occipital lobe symptoms of dementia

A

Disorder of vision.

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6
Q

what conditions of dementia can be treated

A
depression
Hypothyroidism
B12 deficiency
Neurosyphilis
Normal pressure hydrocephalus- CSF shunting is used to treat it, tested via lumbar puncture and see if it gets better.
subdural haematoma
encephalitis.
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7
Q

what drugs are used to treat dementia.

A

anticholinergic, sedatives, narcotics, H2 blockers.

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8
Q

what is the most common type of dementia

A

alzheimers dementia

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9
Q

what are the symptoms in Lewy body dementia

A

Psychiatric problems followed by motor problems.
Parkinson’s- motor and sensory deficit originate in the brainstem and migrate to the cortex.
Can have rare genetic causes- 1 single gene mutation results in parkinsosn and 2 results in lewy body- they are closely related

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10
Q

define parkinsons and which subtype of dementia is it associated with

A

motor and sensory deficit originate in the brainstem and migrate to the cortex.
Lewy body

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11
Q

Does Huntington’s disease cause dementia

A

Yes

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12
Q

define vascular dementia

A

subcoritcal- only affects a small region of the brain near the blood vessels which have been affected.

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13
Q

Is there any treatment for vascular dementia

A

No

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14
Q

what are the 4 classifications of dementia (based on site)

A

anterior-behaviour change
Posterior- cognitive function, memory and language, mo changes in behaviour.
subcortical-forgetful and slow poor ability to use knowledge associated with other neurological signs and movement disorders.
cortical- high cortical abnormalities- dysphasia, agnosia and apraxia.

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15
Q

which type of dementia is associated with hunting tons and normal pressure hydrocephalus?
anterior vs posterior

A

anterior

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16
Q

What are the signs of frontotemporal alzheimer’s

A

Behaviour
Non-fluent progressive aphasia
Semantic dementia (ideas and concepts)
Dementia with lewy body

17
Q

Is Parkinson’s motor or sensory loss

A

both (mainly motor)

18
Q

what are the 3 signs of Parkinson’s plus syndrome

A

– Progressive supranuclear palsy
– Multiple system atrophy
– Corticobasal degeneration

19
Q

How are neurodegenrative disease currently classified

A

Tauopathies
Ubinquinopathies
Synucleopathies

20
Q

what dementias a are included in Tauopathies

A

FTD and FTDP-17.
PSP
Corticobasal degeneration
Alzheimer’s

21
Q

what type of dementias a are included in ubiquinopathies

A

MND and MND demenita

semanctic dementia

22
Q

what type of dementias are associated with synuceloinopathies

A

Parkinson’s disease
Dementia with lewy bodies
MSA- multiple systems atrophy

23
Q

what is the grid of symptoms found in normal pressure hydrocephalus

A

dementia, gait disturbance and urinary incontinence

24
Q

what is a common presentation of normal pressure hydrocephalus

25
Is the MMSE score normal in normal pressure hydrocephalus
Yes
26
what pattern is seen on a EEG in | transmissible spongiform encephalopathies
triphasic waves on repeat
27
give an example of an autoimmune encephalitis
encephalitis due to voltage gated potassium channel antibody (VKGC ab LE
28
what are the symptoms of voltage gated potassium channel antibody (VKGC ab LE
``` subacute memory loss psychiatric problems behvaiour disturbacne seizures hyponatremia ```
29
what are prion disease dementia aka
Transmissible spongiform encephalopathy
30
pathogenesis of transmissible spongiform encephalopathy
Mental and physical abilities deteriorate and myriad tiny holes appear in the cortex causing it to appear like a sponge