Derm Flashcards

1
Q

Five components of successful use of topical therapies

A
Correct diagnosis
Type of lesion being treated
Medication
Vehicle (the base in which the active medication is delivered)
Method used to apply the medication
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2
Q

Absorb moisture, decrease friction, and help cover wide areas easily

A

Powders

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3
Q

Act as emollients

Occlusive properties – often enhance drug penetration

A

Oils

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4
Q

Evaporate, provide a cooling, soothing sensation, while aiding exudative lesions to dry

A

Liquids

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5
Q

Smooth nonhair skin, thick, hyerpkeratotic leasions options

A

ointment+++
cream++
foam++

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6
Q

Hairy areas

A

solution+++

Foam+++

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7
Q

palms soles

A

Ointment+++
Cream++
Foam++

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8
Q

Infected Areas

A

Solution+++
Foam++
Lotion++

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9
Q

Between skin folds; moist, mascreated lesions

A

Cream
Lotion
Solution
Foam

all ++

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10
Q

Water suspended in oil

A

oinment

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11
Q

Ointments do what

A

Excellent lubrication, facilitates heat retentions, decreases transepidermal water loss, provides enhanced medical absorption, semi- occlulsive.

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12
Q

Ointments generally most are

A

potent vehicles (due to occlusive effectds)

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13
Q

Oinments are what and are not what

A

greasy and not useful in hair areas

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14
Q

Oinment use

A

Apply two to three times per day to dry, lichenified lesions, particularly after moisturizing the skin

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15
Q

Semi-solid emulsions of oil in 20 to 50% water and can be washed off with water

A

Creams

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16
Q

Creams are

A

Cosmetically appealing vehicles for delivering topical medications

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17
Q

Same medication – cream formulations are usually

A

stronger than lotions, but less potent than ointments.

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18
Q

Lotions are the least

A

potent topical tehrapies

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19
Q

lotions are useful in

A

hairy areas, conditions were large areas have to be treated

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20
Q

Lotions are Pwder in

A

Powder-in-water (shake container before application)

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21
Q

Lotions do what

22
Q

lotions provide a

A

colling and drying effect

23
Q

lotions are useful in treating

A

treating moist dermatoses and/or pruritis.

24
Q

Solutions contain

A

Contain water or non-aqueous (such as alcohol or propylene glycol)

25
Solutions bath
Bath soaks and open wet dressings provide coolness and aid in drying exudative lesions by means of evaporation
26
Solutions vasoconstictions results in
in decreased local blood flow and reduction in local edema
27
Wet Dressings permit
Permit the cleansing of exudate while maintaining drainage in infected lesions (e.g., ulcers)
28
Wet Dressings should be changed
Should be changed every 6 hours for 2 to 3 days before judging their effectiveness
29
Wet Dressings - closed
Closed wet dressings polyurethane plastic (e.g., Saran Wrap), which allows heat to be retained, prevents evaporation, and causes maceration
30
Gels are
Oil-in-water emulsion with alcohol in the base
31
Gels dry in a
Dry in a thin, greaseless, non-staining film
32
Gels combine
Combine best therapeutic advantage of ointments with the best cosmetic advantages of cream
33
Gels transparent
Transparent, colorless, semi-solid emulsions that liquefy on contact with the skin
34
Gels hair
Hair-bearing areas, treating acne
35
Foams pressurized
Pressurized collections of gaseous bubbles in a matrix of liquid film
36
Foams spread
Spread readily, easier to apply than other preparations, particularly for inflamed skin, scalp dermatoses
37
Foams more cosmetically
More cosmetically acceptable (which can lead to high compliance)
38
Topical Corticosteroids induce
Induce an inflammatory response in the skin by a variety of mechanisms
39
Topical Corticosteroids anti-
Anti-mitotic activity – scaling dermatoses
40
Topical Corticosteroids cutanious
Cutaneous vasoconstriction
41
Topical Corticosteroids divided into
Divided into seven groups (group one = super-high potency, group seven = least potent)
42
Topical Corticosteroids betetr
absorbed through areas of inflammation and desquamation than normal skin, more readily through the thin stratum corneum of infants than the skin of adults
43
Seven groups of corticosteroids
``` Group 1 (super-high potency Group 2 (high potency) Group 3 (high potency) Group 4 (medium potency) Group 5 (lower-mid potency group 5) Group 6 (low potency) Group 7 (least potent) ```
44
Regional Differences in Percutaneous Absorption
``` Sole of foot – 0.14 percent Palm – 0.83 percent Forearm – 1 percent Scalp – 3.5 percent Forehead – 6 percent Mandible – 13 percent Genitalia – 42 percent ```
45
Corticosteroid Selection can depend
Can depend on what is being treated
46
Corticosteroid Selection start
Start with lowest potency
47
Corticosteroid Selection use
Use shortest time possible
48
Corticosteroid Selection super high
Super high potency corticosteroids - severe dermatoses over nonfacial/nonintertriginous areas (psoriasis)
49
Corticosteroid Selection medium to
Medium to high potency - mild to moderate nonfacial/nonintertriginous dermatoses.
50
Corticosteroid Selection eyelid and
Eyelid and genital dermatoses - low-potency topical corticosteroids for limited time periods.
51
Corticosteroid Selection low to mediam
Low to medium strength - large areas are treated because of the likelihood of systemic absorption