Diabetes - Oral agents Flashcards Preview

Nursing Fundamentals II > Diabetes - Oral agents > Flashcards

Flashcards in Diabetes - Oral agents Deck (11):
1

Sulfonylurea (2nd generation)

Glipizide (Glucotrol)
Glucotrol XL (extended release tab)
Glimepiride (Amaryl)

2

Sulfonylurea (2nd generation) - action

Increase insulin secretion from pancreatic islet cells and increase sensitivity of insulin receptors on target cells

3

Meglitinide Analogs

Repaglinide (Prandin)
Nateglinide (Starlix)

4

Meglitinide Analogs - action

Increase insulin secretion from pancreatic islet cells; prevent post-meal blood glucose elevation

5

Biguanides

Metformin (Glucophage)

6

Biguanides - action

Lowers basal and post-meal blood glucose by reducing hepatic glucose production and increase tissue sensitivity; reduces insulin resistance

7

Alpha Gucosidase Inhibitors

Acarbose (Precose)
Migitol (Glyset)

8

Alpha Gucosidase Inhibitors - action

Prevent post-meal blood glucose elevation; block enzymes in the small intestine that break down complex carbs; digestion of glucose is delayed

9

Thiazolidinediones

Pioglitazone (Actos)
Rosiglitazone (Avandia)

10

Thiazolidinediones - action

Improves tissue sensitivity to insulin; reduce insulin resistance; inhibit hepatic glucogenesis

11

Combination Drugs

combine with metformin