Digestion and macronutrients Flashcards

1
Q

Herbivore means

A

Diet is plant based

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2
Q

Carnivore means

A

Diet is animal tissue

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3
Q

Omnivore measn

A

diet is both

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4
Q

Obligate carnivore means

A

Must eat animal tissue

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5
Q

Hyper carnivore means

A

> 70% of diet is animal tissue

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6
Q

Mesocarnivore means

A

50-70% of the diet is animal tissue

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7
Q

Hypocarnivore means

A

<30% of the diet is animal tissue

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8
Q

Herbivore digestion

A

Host (cow, sheep, horse)
Finds forage
Provides fermentation vat
rumen/cecum
Large intestine
Buffers fluid
Saliva
Intestinal secretions
Removed end products
Controls temp
Microbes (bacteria, fungi, protozoa)
Extracellular digestion
Converts carbohydrates to volatile fatty acids
Acetate
Butyrate
Propionate
Degrade and synthesize amino acids
Synthesize B vitamins
Is a symbiotic relationship

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9
Q

Efficient digesters

A

Fermentation occurs towards the start of the digestive tract
More tolerant of poor-quality diets
Do not require a dietary source of essential amino acids or essential fatty acids
Do not routinely require B vitamin supplementation

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10
Q

Hindgut fermenters

A

Fermentation is in the large intestine
Only VFAs, minerals and water are absorbed in the large intestine
Dependent on diet to supply essential amino acids and vitamins
Large intestine fermentation allows capture form plant cellulose and other plant fibres

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11
Q

omnivore digestion

A

Require dietary B vitamins
Dietary essential fatty acids (a-linolenic, linoleic)
Essential amino acids
Methionine, cysteine, lysine often limiting
Dietary carbohydrates are the importanta blood glucose source
Limited ability to digest fiber

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12
Q

Carnivore digestion (cats)

A

Specific dietary requirements. Essential dietary nutrients include
B vitamin
α-linolenic, linoleic and arachidonic acid (found in animal derived sources)
Essential amino acids
Taurine (a sulfonic amino acid synthesized in our other species from cysteine)
Protein is a major source of blood glucose
Very limited fiber digestions

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13
Q

Carbohydrates provide what

A

Provides a source of energy (3.5 kcal/g)
Can be completely replaced by protein and lipid as an energy source for maintenance (ie, not essential)

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14
Q

Carbohydrates change when and why

A

However; During growth, gestation, and lactation dietary carbs are required for dogs and cats
Takes too much energy to synthesise glucose from alternative sources
Normal protein intake may be inadequate to support gluconeogenesis
So carbs are conditionally essential

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15
Q

Starches and digestibility

A

Common sources are grain and potatoes
In small animals, usually cooked and ground to improve their digestibility
The grinding of corn into a meal increases digestibility from 79 to 94%
Uncooked starch ferments in the large intestine, generating intake of water
Starch broken down into glucose by pancreatic enzymes (amylase) and digestive cells of small intestine

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16
Q

Starches and food texture

A

Extruded pet food diets (dry food)
Ground, heated with steam, forced through holes and cut into shapes
The gelatinized starch helps hold the food together and gives it texture
Gravies and sauces (wet foods)
Dextrins, corn syrup, and starches
Dextrins are a polymer of glucose
Used to thicken gravy

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17
Q

Fiber types

A

Ability to be fermented by bacteria
Fermentable
Non-fermentable
Ability to dissolve in water
Soluble
insoluble

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18
Q

Crude fiber is

A

Insoluble fibre
Mainly lignin and cellulose, can underestimate hemicellulose

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19
Q

Neutral digestible fibre is

A

Ligin, cellulose and hemicellulose

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20
Q

Acid digestible fibre is

A

Lignin and cellulose
NFD-ACF = hemicellulose

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21
Q

Nitrogen free extract is

A

Digestible starches and soluble fibres

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22
Q

Total dietary fiber is

A

All fibre (soluble and insoluble)

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23
Q

What are the different fiber measurements

A

Crude fiber
Neutral digestible fiber
acid digestible fiber
Nitrogen free extract
Total dietary fiber

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24
Q

Importance of fiber for herbivores

A

Major energy source in herbivores only
Fermented to VFAs
Acetate and butyrate
What about propionate?
Starches and sugars

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25
Importance of fiber
VFAs stop growth of some pathogens Butyrate is preferred energy source for colon epithelial cells Required for normal GI function in all species Both physical properties and VFA production are important Helps maintain normal fecal consistency
26
How does fiber help regulate fecal consistency
Fiber speeds intestinal transit in dogs with slow or normal transit Fiber slows transit in dogs with rapid intestinal transit Maintains stool quality- size and consistency
27
Why is fiber important in disease
In dogs, an increase in fibre is typically used to treat colitis In cats, fibre can be used to help manage constipation
28
Prebiotics means
substances that selectively promote growth of beneficial bacteria
29
Fiber as prebiotics
Many are types of dietary fiber made from oligosaccharides Fructooligosaccharides Pectic oligosaccharides Not digested by mammalian enzymes Preferentially by fermented by beneficial microbes Bacterial fermentation of fiber creates short chinese fatty acids Provides 70% of the energy needed by enterocytes May be added to foods to promote gut health
30
Fats characteristics
Solid at room temp Generally saturated fatty acids
30
Types of lipids
Fats Oils Many are triglycerides Lipids are energy dense (8.5 kcal/g)
31
Oils characteristics
Liquid at room temp Mostly unsaturated fatty acids
32
Long chain triglycerides
Most common lipid in diet Canola or soybean oil, animal fats Transported from the small intestine in the lymphatics
33
Medium chain triglycerides
More rapidly hydrolyzed in the small intestine than long chain triglycerides Transported in the portal vein Small component of common diets Coconut oil is a good source Used therapeutically in monogastrics When there are problems in digesting long chain triglycerides To boost brain function
34
Types of lipids: carbon bonds
Saturated Unsaturated Trans saturated
35
Saturated lipids
No double bond Tallow (animal fat) about 40% saturated
36
Mono-saturated
Type fo unsaturated lipid One double bond Olive, avocado, sunflower, canola, sunflower oils .50% monounsaturated
37
Poly saturated lipids are
Type of Unsaturated lipid Several double bonds Found many plant oils Fish oil is rich in omega-3 fatty acids
38
Trans saturated lipids are
Artificial fats made when plant fats are hydrogenated Hydrogen atoms added in an unnatural manner Block normal metabolism in the body
39
Functions of lipids
An energy source More than twice the energy density of carbohydrates Supplies 60% of body's energy needs at rest Stored as adipose tissue Insulation and protection Structural in cell membranes As precursors of eicosanoids and prostaglandins Signalling molecules important in cell regulations and inflammation Carry fat-soluble vitamins Contribute flavour, aroma and texture
40
Essential fatty acids
Mammals cannot interconvert, or synthesise from new, omega 3 and omega 6 series fatty acids Need a dietary source of each Omegas are polyunsaturated fatty acids, need for the carbon location of the first double bond Omega 6 vs omega 3 Ruminants have no dietary essential fatty acid requirements EFAs are synthesised in rumen
41
Essential fatty acids
Omega 3 and omega 6
42
omega 3 fatty acid is and sources
Alpha linolenic acid is essential source in diet Precursor of anti-inflammatory mediators Docosahexaenoic acid and eicosapentaenoic acid Sources Fish oil Canola oil Flax (linseed oil) Marine microalgae
43
Omega 6 fatty acids is and sources
Linoleic acid is the essential dietary source Required to make inflammatory mediators Cats also require arachidonic acid, cannot elongate linoleic acid Sources Chicken fat Sunflower oil
44
Proteins are
Proteins are groups of amino acids joined together by peptide links in different quantitative and sequences Protein quality can be affected by the types of amino acids they supply Digestion breaks the proteins into their amino acids, which are sued by the body Excess protein in the diet is deaminated
45
What does excess protein in the diet do
Excess protein in the diet is deaminated The ammonia is converted to urea and excreted The carbon skeleton is used for energy or fat
46
Function of proteins
Build or replace body tissue Integral part of body organs, tissues, hair, nails and cartilage Function as enzymes (eg. digestive) and hormones (eg, insulin) Act as carriers Hemoglobin carrying oxygen and CO2 Part of the immune system Immunoglobulins Provide energy (3.5 kcal/g)
47
Dietary essential amino acids
Cannot be synthesized by the mammal and are essential in the diet Which ones vary with the species Cats have the greatest number of dietary essential amino acids requirements
48
Dietary non-essential amino acids
Do not need to be supplied by their diet Can be synthesized from precursors
49
Conditionally essential amino acids
Required in certain states
50
Types of essential amino acids
Dietary essential aa Dietary non-essential aa Conditionally essential aa
51
Measuring proteins
Labels are required to report crude protein content of the diet Calculated by measuring total nitrogen content of diet Includes True protein Non-protein nitrogen Ammonia, nitrates, urea Infamously- melamine
52
Melamine is and contains
Melamine is a plastic Used in plates Contains nitrogen
53
Why is nitrogen in melamine important and what is doe about it
Waste plastic was ground and added to protein meals in China These were used in baby food and pet food Breaks down to produce cyanuric acid The combo of melamine and cyanuric acid is very toxic to the kidneys Led to improved feed testing Previously testes just for common toxins New reputable pet food companies test feed to make sure it is normal Often performed using spectroscopy
54
Apparent digestable protein
Crude Protein Eaten – Crude Protein in Feces Changed to amino acids in large intestine affect apparent digestible protein Amino acids removed or produced in the large intestine not available to the animal
55
Ileal digestable protein
Crude Protein Eaten – Crude Protein at Ileum Not confounded by protein fermentation in the large intestine Highly accurate, but highly invasive AKA true digestible protein
56
Biological value of protein
The usefulness of absorbed protein in building new tissue Determined by amino acid composition If amino acid composition of dietary protein is similar to that of the animals tissues then it has biological value Protein from meat (not bone), liver and heart, milk (casein and whey) have an amino acid composition that parallels an animals needs Readily converted to tissue proteins High biological value If protein completely missing an amino acid, cannot be used to make body protein Has zero biological value Protein sources may be mixed Deficiencies in amino acids in one protein are balance by amino acids from another
57
Ruminants and protein
Ruminal microbes Digest dietary protein Amount depends on structure of proteins Degrade and interconvert amino acids Can synthesize amino acids using A non protein nitrogen source (NPN) A carbohydrate skeleton Dietary energy Typically grain or molasse No amino acid is essential in the diet
58
Limitations of feeding NPN in general
Microbes and undigested dietary protein cleave the rumen and are digested in small intestine
59
Limitations of feeding NPN for ruminats
Generally need at least ⅔ of nitrogen as a dietary protein Not enough dietary energy to synthesise all the amino acids Have a higher protein requirements if high producing Remainder can be non protein nitrogen (NPN)
60
Common sources of NPN
Common NPN sources are ammonia and urea Ammoniated feed Highly toxic if poorly mixed or too much injected into feed (hay)
61
NPN toxicosis
Rate of ammonia production exceeds ability of microbes to utilize it Ammonia builds up in the rumen Liver detoxification overwhelmed Elevated blood ammonia levels Ammonia in the rumen is generally absorbed into systemic circulation and detoxified by the liver via the urea cycle
62
Urea toxicity
Urea is widely used as a NPN source Safer than ammonia Minor excesses: decreased production
63
Major urea excess signs
Muscle tremors Salivation Bellowing Bruxism Incoordination and weakness Rapid earth, often close to urea feeder
64
Monogastrics and protein
Horses, omnivores, carnivores Require a dietary source of certain amino acids Tryptophan, lysine and methionine often of major concern
65
Bacterial fermentations for monogastrics and protein
Occurs in large intestine Any amino acids produced by microbes cannot be digested or absorbed by the host because this only occurs in the small intestine
66
Methionine is
Sulphur amino acid (also cystine) Essential in hair protein (keratin) synthesis Richly present in animal protein sources, eggs and fish
67
Arginine is
Key role in immune system and urea excretion Beneficial in heart and kidney disease Richly present in animal tissues and gelatin
68
Lysine is
Major role in protein synthesis Deficiency slows growth in puppies/kittens Meat and milk are good food sources
69
Some essential aa
Methionine Arginine Lysine
70
Taurine functions
Required for retina, heart and brain health Important for reproduction functions Antioxidant
71
Taurine deficiencies can cause
Reproductive failure Retinal degeneration Dilated cardiomyopathy
72
Taurine and DCM
Conditionally essential in dogs? Connection b/w certain breeds of dogs and the development of DCM These dogs do respond to taurine supplementation Recent concern that certain types of diets (boutique, exotic, grain free) were being linked to development of DCM Taurine deficiency cause? Most dogs did not have low taurine levels However improved after diet change
73
Protein deficiency is
Inadequate protein or lack of essential amino acids in the diet Protein is required for all aspects of growth, production and maintenance Growing animals most susceptible
74
Why are growing animals more susceptible to protein deficiency
Higher protein requirements Less successful at competing for food Reduced growth
75
What does a protein deficiency in lactating dairy cows cause
High dietary protein requirements Microbes cannot make enough Poor production Possibly excessive weight loss