Digestive System II Flashcards

1
Q

What are the four layers of the GI tract?

A

1) mucosa (mucous membrane)
2) submucosa
3) Muscularis externa
4) Adventitia or Serosa

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2
Q

What is the thin covering or sac that holds all the intestines and organs in place in the torso of the body?

A

mesentaries

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3
Q

The inner layer of the GI tract, the mucosa, is composed of what three layers (from innermost to outermost)?

A

1) epithelium
2) lamina propria
3) muscularis mucosae

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4
Q

The third layer of the GI tract, the musculari externa, is composed of what two layers (from innermost to outermost)?

A

1) inner circular layer
2) outer longitudinal layer

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5
Q

The external layer of the GI tract, the adevntitia or serosa, is composed of what?

A

1) areolar tissue
2) mesothelium

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6
Q

Which layer of the GI tract wall is composed of smooth muscle?

A

muscularis externa

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7
Q

What are the two nerve plexi in the GI tract wall?

A

1) submucosal nerve plexus
2) myenteric nerve plexus

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8
Q

What is the nervous system the controls the gut called?

A

Enteric nervous system

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9
Q

Which nerve plexus of the ENS regulates mucosal tension and folding, and secretion of mucosal glands?

A

submucosal nerve plexus

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10
Q

Which nerve plexus regulates peristalsis of the submucosal plexus?

A

myenteric plexus

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11
Q

The esophagus extends from which two functioning points at the cardiac orifice?

A

From the upper esphogeal sphincter to the lower esophogeal sphincter

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12
Q

What kind of epithelium makes up the esophagus?

A

nonkeratinized stratified squamos epithelium

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13
Q

Which two glands are found in the esophagus?

A

1) mucous submucosal glands
2) esophageal glands

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14
Q

The muscularis externa has an inner ____ muscle layer and an outer ____ muscle layer.

A

circular; longitudinal

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15
Q

Which layer in the esophagus are esophageal glands located?

A

lamina propria

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16
Q

What is the boundary located between the submucosal glands and the esophageal glands?

A

gastroesophageal junction

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17
Q

What are folds within the stomach called that grind chunks of food?

A

gastric rugae

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18
Q

Food enters into the stomach from the ____ and exits the stomach through the ____.

A

esophagus; duodenum

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19
Q

The muscular layers of the stomach are found in what layer?

A

muscularis externa

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20
Q

What is the mucous layer of the stomach composed of?

A

1) epithelium
2) gastric pits
3) glands
4) lamina propria
5) muscularis mucosae

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21
Q

What is the submucosa layer of the stomach composed of?

A

1) connective tissue
2) blood vessels
3) submucosal plexus

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22
Q

What is the muscularis externa layer of the stomach composed of?

A

1) three muscle layers
2) myenteric plexus

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23
Q

Which special cells are associated with gastric pits (two kinds)?

A

parietal cells and goblet cells

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24
Q

Which kind of epithelium are gastric pits lined with?

A

simple columnar epithelium

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25
What opens into the base of each gastric pit?
gastric glands
26
Which kind of glands dominate the stomach? Why is this?
mucous glands; it helps prevent corrosion
27
What are the three glands found in the stomach?
1) cardiac glands 2) pyloric glands 3) gastric glands
28
Which glands of the stomach are composed of shallow gastric pits, a long gland, and is purely mucous? Which region are they found?
cardiac glands; cardiac region
29
Which glands of the stomach have deep gastric pits, are shorter glands, are loosely arrayed in the lamina propria, and are purely mucous? What region are they found?
pyloric glands; pyloric region
30
Which glands of the stomach have a mouth, neck, body, and fundus and have five types of cells? What region are they found?
gastric glands; fundus, body, and most of the pyloric region
31
What are the five cells of the gastric glands?
1) stem (regenerative) cells 2) mucous neck cells 3) parietal (oxyntic) cells 4) chief (zymogenic) cells 5) enteroendocrine cells
32
Which two cells of the gastric glands secrete proteins?
* parietal (oxyntic) cells * chief (zymogenic) cells
33
What do **parietal cells** secrete in the gastric glands?
* hydrochloric acid (HCl) - pH 8 * Intrisic factors
34
What do **chief cells** secrete in the gastric glands?
* pepsinogen * gastric lipase (infants) * chymosin (infants)
35
What do **enteroendocrine cells** secret in the gastric glands?
* hormones * paracrines
36
What do **mucous neck cells** secrete in the gastric glands?
mucus
37
Purposes of hydrochloric acid: 1) activates ____ and ____ lipase 2) breaks up connective tissues and ____ fiber (collagen and cellulose) 3) converts Fe3+ to ____. 4) nonspecific disease resistance aka ____ properties
1) pepsin; lingual 2) plant 3) Fe2+ 4) antibacterial
38
Which region of the stomach have the deepest gastric pits?
pyloric stomach
39
The gastric pits in the pyloric region of the stomach are somewhat ____, giving a sawtooth appearnce.
coiled
40
What do **G cells** in the stomach secrete?
gastrin
41
What do **ECL** cells in the stomach secrete?
histamine
42
What do **D cells** in the stomach secrete?
somatostatin
43
What is the *function* of the **parietal cells** secretion?
* Kills microbes and activates pepsinogen * Bind Vitamin B12 to allow its absorption
44
What is the *function* of the **chief cells** secretion?
* protein digestion * fat digestion
45
What is the *function* of the **G cells** secretion?
stimulates gastric acid secretion
46
What is the *function* of the **ECL cells** secretion?
stimulates gastric acid secretion
47
What is the *function* of the **mucus-neck cells** secretion?
protects stomach epithelium from acid
48
What is the *function* of the **D cells** secretion?
inhibits gastric acid secretion
49
Even though HCl kills most bacteria in the stomach, which bacteria sits deep within the stomach and can cause ulcers?
H. pylori
50
At what point does the small intestine start, and where does it end?
starts - pyloric sphincter ends - ileocecal valve
51
What is the order of the regions of the small intestine called starting from where food travels through **first** to where it **ends**?
1) duodenum 2) jejunum 3) ileum
52
Which portion of the small intestine includes chyme, bile, and pancreatic juice?
duodenum
53
Which portion of the small intestine is the site of most digestion and absorption?
jejunum
54
Which portion of the small intestine has a thinner wall, and is the site of the rest of digestive and absorption properties?
ileum
55
What is the upper region of the small intestine called (duodenum region)?
epigastric region
56
What is the middle region of the small intestine called (jejunum)?
umbilical region
57
What is the lower region of the small intestine called (ileum)?
hypogastric region
58
What are the four things that increases intestinal surface area?
1) length 2) circular folds 3) villi 4) microvilli
59
What is the total surface area of the small intestine?
~2150 square feet
60
What is the main factor which increases surface area in the small intestine which is mainly prevalent in the jejunum?
circular folds (pilcae circulares, valves of Kerckring)
61
Why is a large surface area important in the small intestine?
* slows the progression of chyme * makes chyme spiral down the intestine * increases epithelial contact for digestion and absorption
62
Which type of villi has a ridge-like appearance?
foliate villi
63
Which type of villi has a tounge-shaped appearance?
linguiform villi
64
Which component of villi helps transport lipid molecules?
lacteal
65
What are the absorption cells called in villi?
enterocytes
66
What type of cells are located on villi and aid in secretions (different from absorption cells?
goblet cells
67
What is a dense cytoskeleton aggregation at the apical pole of the cell? What filament is anchored here?
terminal web; actin filaments
68
Which intestinal cells secrete antibacterial lysozyme?
Paneth cells
69
What glands within the duodenum are located in the submucosa?
Duodenal glands
70
What is another name for duodenal glands?
Glands of Brunner
71
Which portion of the small intestine has Peyer's patches?
ileum
72
Which portion of the small intestine have the shortest villi and more lymphocytes than anywhere else?
ileum
73
What are all the parts of the large intestine?
1) cecum 2) appendix 3) colon 4) rectum 5) anal canal
74
What are the different regions of the colon?
1) ascending 2) transverse 3) descending 4) sigmoid
75
What is the main functions of the large intestine?
* absorption of water and electrolytes * water conservation * consolidation of residue into feces * defaction
76
What tissue is the appendix mainly composed of?
GALT
77
What surface area enhancer does the colon have? What does it not have?
have - intestinal crypts doesn't have - villi, circular folds
78
In the intestinal crypts of the colon, which cells give rise to neutrophils which help with anibacterial defense?
STEM cells
79
What are the two sphincters of the anal canal?
* internal anal sphincter * external anal sphincter
80
Which sphincter in the anal canal is involuntary?
internal anal sphincter
81
Which sphincter in the anal canal is voluntary?
external anal sphincter
82
Which kind of muscle controls the external anal sphincter?
skeletal muscle