DNA replication (I2I) Flashcards

(23 cards)

1
Q

DNA replication

A

Production of two identical DNA molecules from one original template molecule.

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2
Q

DNA replication take place after cell division.True or False?

A

False
before cell division (s phase)

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3
Q

DNA replication takes place during _____ of cell division.

A

S phase (synthetic phase)

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4
Q

DNA replication is ______.Why?

A

semiconservative
bcus new made strands contain single strand of template DNA.

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5
Q

DNA replication takes place on ______ of chromosomes.

A

Origin of replication

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6
Q

Types of DNA in prokaryotes and its origin of replication

A

Circular DNA
Only one origin of replication

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7
Q

Types of DNA in eukaryotes and its origin of replication

A

Linear DNA
Thousands of origin of replication

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8
Q

DNA replication directs ______ the replication fork.

A

towards the replication fork

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9
Q

The template strands must be separated in order to replicate.True or False?

A

True

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10
Q

Replication takes place on both strands simultaneously.True or False?

A

True

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11
Q

Replication takes place from every origin of replication at the same time in eukaryotic cell.True or False?

A

True

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12
Q

Enzyme that separates two strands of template DNA

A

Helicase

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13
Q

Function of Helicase

A

separate two strands of template DNA

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14
Q

Function of single strand binding proteins

A

Stablizie the unwound template strands

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15
Q

Function of topoisomerase

A

Relieve super coiling by breaks and rejoins the strand ahead the replication fork.

(DNAရဲ့backboneမှာရှိတဲ့phosphodiester bondကိုဖျက်ပြီးပြန်ဆက်ပေး)

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16
Q

Enzymes that synthesize DNA

A

DNA polymerase 3

17
Q

Function of DNA polymerase 3

A

to synthesize new DNA strands by adding nucleotide

18
Q

Can DNA polymerase 3 initiate replication by itself?

A

No
it need primer in order to initiate replication.

19
Q

Function of primase

A

to synthesize RNA primer in order to initiate replication

20
Q

Nucleoride of Primer

A

RNA primer -Ribonucleotide

21
Q

DNA pol 3 can synthesize new strands only in ______ direction.

A

5’ to 3’ direction

(3’ OH endကိုပဲnucleotides အသစ်တွေပေါင်းပေးနိုင်)

22
Q

Replication direction according to newly synthesized strand

A

5’ to 3’ direction

23
Q

Replication direction according to template strand

A

3’ to 5’ driectionကိုပဲဖတ်ပြီး အသစ်တွေထည့်သွား