DNA viruses

Question 1

All enveloped viruses acquire their envelope from plasma membrane except for

Answer 1

Herpes virus (from nuclear membrane)

Question 2

Purified nucleic acids of most dsDNA except for ______ are infectious

Answer 2

Poxviruses and HBV

Question 3

Only live attenuated vaccine that may be given to HIV positive patients

Answer 3

MMR

Question 4

DNA viruses

Answer 4

DNA viruses are HHAPPPPy viruses
Hepadna
Herpes
Adeno
Pox
Parvo
Polyoma
Papilloma

Question 5

All DNA viruses have double-stranded DNA except

Answer 5

Parvovirus

Question 6

All DNA viruses have linear DNA except

Answer 6

Papilloma, polyoma, hepadna

Question 7

All DNA viruses are icosahedral except

Answer 7

Poxvirus

Question 8

All DNA viruses replicate in the nucleus except

Answer 8

Poxvirus (cytoplasm)

Question 9

Condition with bright red cheek rash (slapped cheeks) with fever coryza and sore throat

Answer 9

Erythema Infectiosum (Fifth Disease)

Question 10

Etiology of Erythema Infectiosum (Fifth Disease)

Answer 10

Parvovirus B19

Question 11

Causes transient but severe aplastic anemia in children sickel cell anemia, thalassemia or spherocytosis

Answer 11

Parvovirus B19

Aplastic crisis

Question 12

Fetal infection caused by Parvovirus B19

Answer 12

Hydrops fetalis (2nd trimester)

Question 13

Only virus with fiber (Penton fiber)

Answer 13

Adenovirus

Question 14

Causes hemorrhagic cystitis

Answer 14

Adenovirus

Question 15

Papilloma virus infects squamous cells and induce formation of cytoplasmic vacuole

Answer 15

Koilocytes

Question 16

What genes in Papilloma virus encode proteins that inactivate tumor suppressor genes

Answer 16

genes E6 and E7

Question 17

HPV that causes skin and plantar warts

Answer 17

HPV 1-4

Question 18

HPV that causes genital warts (condylomata acuminata) and respiratory tract papillomas

Answer 18

HPV 6 and 11

Question 19

HPV that causes carcinoma of cervix, penis and anus

Answer 19

HPV 16,18, 31,33

Question 20

DOC for HPV

Answer 20

Genital warts : Podophyllin
Skin warts: Liquid nitrogen
Plantar warts: Salicylic acid

Question 21

Causes progressive multifocal leukoencephalopathy (PML) in patients with AIDS

Answer 21

JC Polyoma virus

Question 22

Causes hemorrhagic cystitis and nephropathy in patients with solid organ and bone marrow transplant

Answer 22

BK Polyoma virus

Question 23

Site of latency period of herpes virus

Answer 23

HSV-1 - trigeminal ganglia

HSV-2 Lumbosacral ganglia

Question 24

DOC for herpes

Answer 24

Acyclovir

Question 25

Site of latency period for Varicella zoster virus

Answer 25

Dorsal root ganglia

Question 26

Condition where in all stages of the disease are present at a single time

Answer 26

Varicella

Question 27

A syndrome that is a complication of varicella

Answer 27

Reye's syndrom

Question 28

A condition where in there is involvement of geniculate ganglion causes facial nerve paralysis

Answer 28

Ramsay hunt syndrome / Herpes zoster oticus

Question 29

Blueberry muffin syndrome

Answer 29

CMV Congenital rubella Disseminated Neuroblastoma

Question 30

Causes Heterophil-negative mononucleosis

Answer 30

CMV

Question 31

DOC for CMV

Answer 31

Ganciclovir

Question 32

3 causes of mononucleosis

Answer 32

CMV & Toxoplasmosis ( heterophil negative) | EBV (heterophil positive)

Question 33

Virus associated with burkitt's lymphoma

Answer 33

EBV

Question 34

Virus associated with nasopharyngeal CA in chinese people and hairy leukoplakia in AIDS patient

Answer 34

EBV

Question 35

Virus associated with Kaposi's sarcoma

Answer 35

Human Herpesvirus -8

Question 36

Largest virus

Answer 36

Smallpox

Question 37

Disease with pinkish papular skin lesions with an umbilicated center

Answer 37

Molluscum contagiosum | Tx. Cifodovir

Question 38

Only DNA virus that produces DNA by reverse transcription with mRNA as the template

Answer 38

Hepatitis B virus

Question 39

DOC of Hepatitis virus

Answer 39

Interferon alpha | Lamivudin

Question 40

Associated with Polyarteritis nodosa

Answer 40

Hepatitis B